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Cuscuta chinensis is a commonly used traditional Chinese herbal medicine. Cuscuta chinensis has a long history of clinical application in the treatment of varieties of ocular diseases. This review summarized the literatures related to its clinical applications, research progresses in the ophthalmic pharmacology and active ingredients. It was aimed to provide a theoretical basis for the further development and utilization of Cuscuta Chinensis as an effective medication.
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?AlM: To explore the effects of the prescription of reinforcing kidney, nourishing blood, improving eyesight on the oxidative stress model of ARPE-19 cells induced by acrolein. ?METHODS:SD rats serum containing the prescription of reinforcing kidney, nourishing blood, improving eyesight and the content of distilled water in serum were prepared. The effects of the prescription and distilled water in serum at different concentration ( 2. 5%, 5%, 10%, 20% and 40%) on cell vitality was observed by cell counting kit ( CCK-8 ) assay. the logarithmic phase of ARPE-19 cells were pretreated by different concentrations (1. 25%, 2. 5%and 5%) of the prescription serum and distilled water in serum for 24h. Then it was treated with 75μmol/L acrolein for 24h. Cell vitality was observed by CCK-8 assay. The change of cell nucleus was detected by DAPl staining . ?RESULTS: 2. 5% and 5% serum had no effect on cell viability (P>0. 05), while 10%, 20%, 40% serum could inhibit cell viability (P ?CONCLUSlON: The prescription of reinforcing kidney, nourishing blood, improving eyesight has the protective effect on ARPE-19 cell damage induced by acrolein.
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Objective To observe the therapeutic effect of Chinese medicine combined with ion-introduction of Radix Astragali Injection (RAI)for herpes simplex keratitis (HSK).Methods Ninety HSK patients (104 affected eyes)were randomized into two groups.Both of the two groups received anti-virus drugs,and the treatment group (45 patients with 53 affected eyes)received oral use of decoction of Chinese medicines (mainly composed of Semen Cassiae,Fructus Viticis,Periostracum Cidadae,Ramulus Uncariae cum Uncis,Fructus Gardeniae,Fructus Forsythiae,Flos Chrysanthemi,Rhizoma Chuanxiong,etc.),and ion-introduction of RAI.The changes of vision and clinical symptoms before and after treatment were observed,and a 2-year follow-up was carried out.Results In the treatment group,19 eyes were cured,27 effective,7 ineffective,and the total therapeutic effective rate being 86.79%;in the control group,10 eyes were cured,21 effective,20 ineffective,and the total therapeutic effective rate being 60.78%.The therapeutic effect in the treatment group was superior to that in the control group (P
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Objective To observe the effect of liver-soothing and spleen-strengthening,essence-tonifying and eyesight-improving herbal medicine for ametropic amblyopia(AA) in children.Methods AA children were randomized into 2 groups.The two groups received treatment of optometry and sight-enhancing device based on microcomputer.Meanwhile,group A(52 affected eyes in 29 patients) received oral use of Ximing Decoction with liver-soothing and spleen-strengthening,essence-tonifying and eyesight-improving actions,which is mainly composed of Radix Curcumae,Radix Pseudostellariae,Radix Panacis Quinquefolii,Fructus Aurantii Immaturus,Herba Agastaches,Flos Buddlejae,Nux Prinsepiae,Fructus Setariae Germinatus,Radix Ophiopogonis,Fructus Crataegi and Massa Medicata Fermentata.Group B(46 affected eyes in 28 patients) received oral use of levodopa additionally.Seven days constituted one treatment course.The treatment lasted 8 courses.Before and after treatment,corrected visual acuity(CVA) was observed.Results In group A,CVA of 13 eyes were improved,AA of 33 eyes cured,6 eyes ineffective,and the total effective rate was 88.46%.In group B,CVA of 10 eyes were improved,AA of 12 eyes cured,24 eyes ineffective,and the total effective rate was 47.83%.The effect in group A was superior to that in group B(P