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AIM:To compare the differences of ocular biometric parameters of age-related cataract between Tibetan and Han ethnic groups, and to analyze the distribution characteristics of ocular biometric parameters in Tibetan cataract patients.METHODS:Retrospective cohort study. A total of 661 patients(1 030 eyes)with age-related cataract confirmed in the hospital between January 2019 and December 2020 were enrolled. The parameters of axial length, anterior chamber depth, keratometry, corneal astigmatism and astigmatic axis were measured by IOL Master 500 in 483 cases(739 eyes)of Tibetan age-related cataract patients and 178 cases(291 eyes)of Han patients.RESULTS:The axial length, anterior chamber depth and corneal astigmatism of the Tibetan patients with age-related cataract were 23.33(22.81, 23.86)mm, 3.04(2.79, 3.30)mm and 0.73(0.47, 1.07)D. The mean keratometry was 43.89±1.35 D. The results indicated that Tibetan cataract patients had shorter axial lengths and smaller keratometry compared to Han patients(all P<0.05). Age in Tibetan patients was negatively correlated with axial length and anterior chamber depth, and positively correlated with keratometry(all P<0.05). Tibetan male patients had longer axial lengths, deeper anterior chambers, and flatter corneas compared to female patients(all P<0.05).CONCLUSION:There were differences in ocular biometric parameters between age-related cataract patients of Tibetan and Han ethnicities. The distribution of ocular biometric parameters in Tibetan cataract patients varied across different age groups and gender groups.
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Purpose: To evaluate the repeatability of biometry and intraocular lens (IOL) power using Galilei G6 and to determine the agreement of its measurements with those of IOL Master 700 and IOL Master 500. Methods: Hundred mature cataract eyes were examined twice with Galilei G6 and the results were compared with those of other two devices. Axial length (AL), minimum (K1), maximum (K2), and mean keratometry, anterior chamber depth (ACD), white-to-white (WTW) diameter, lens thickness (LT), and the calculated IOL power were the studied parameters. The correlation coefficient, within-subject standard deviation (Sw), Bland–Altman method, and 95% limits of agreement (LoA) were used for statistical analysis. Results: The intraclass correlation coefficient (ICC) was above 0.9 for all indices, and the LoA ranged from a minimum of 0.08 mm for AL to a maximum of 0.50 D for K1. Sw also ranged between a minimum of 0.02 for AL, ACD, and WTW and a maximum of 0.13 for K1. In the Galilei G6–IOL Master 700 pair, the narrowest and widest LoA were calculated for AL (0.07 mm) and K2 (0.49 D), respectively. In the Galilei G6–IOL Master 500 pair, the narrowest and widest widths of LoA were calculated for AL (0.17 mm) and K2 (0.92 D), respectively. In the first pair, the LoA of IOL power (0.57 D) were the best for Haigis formula and in the second pair, the best agreement (LoA: 0.35 D) was observed for Holladay-1. Conclusion: Galilei G6 provided repeatable biometric measurements. The agreement between biometry and IOL power calculation was better in the Galilei G6–IOL Master 700 pair compared to the Galilei G6–IOL Master 500
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Objetivo: Comparar las mediciones biométricas realizadas con el IOL Master 500 y el Pentacam AXL. Métodos: Se realizó un estudio transversal en 99 ojos de 99 pacientes miopes con criterio de cirugía fotoablativa, atendidos en el período de enero del año 2019 a enero de 2020, en el Servicio de Cirugía Refractiva del Instituto Cubano de Oftalmología "Ramón Pando Ferrer". Las variables estudiadas fueron edad, sexo, equivalente esférico y características biométricas preoperatorias (longitud axial, profundidad de la cámara anterior y queratometrías), así como su relación, aportadas automáticamente por el IOL Master 500 y el Pentacam AXL para evitar los factores dependientes del operador. El análisis estadístico se realizó con la Prueba t para datos pareados, utilizando una significación del 95 por ciento. Una diferencia con un valor de p < 0,05 fue considerado estadísticamente significativo. Resultados: El 60,61 por ciento de los pacientes eran de sexo femenino y el 39,39 por ciento del masculino, con una edad promedio de 25,67 ± 4,30 años. Se analizaron 51 ojos derechos y 48 izquierdos. El equivalente esférico medio fue de -3,30 ± 1,53 dioptrías. No hubo diferencia estadísticamente significativa entre los valores biométricos (longitud axial, profundidad de la cámara anterior y queratometrías) obtenidos con el IOL Master 500, en comparación con los del Pentacam-AXL (p > 0,05). Conclusión: Las mediciones biométricas (longitud axial, profundidad de la cámara anterior y queratometrías) obtenidas con el IOL Master 500 y el Pentacam-AXL son similares(AU)
Objective: Compare biometric measurements taken with IOL Master 500 and Pentacam AXL. Methods: A cross-sectional study was conducted of 99 eyes of 99 myopic patients with indication of photoablative surgery attending the Refractive Surgery Service at Ramón Pando Ferrer Cuban Institute of Ophthalmology from January 2019 to January 2020. The variables analyzed were age, sex, spherical equivalent and preoperative biometric characteristics (axial length, anterior chamber depth and keratometries) and the relationship to one another, automatically supplied by IOL Master 500 and Pentacam AXL to avoid operator-dependent factors. Statistical analysis was based on the paired T-test with a significance level of 95%. A difference with a p-value < 0.05 was considered to be statistically significant. Results: Of the patients studied, 60.61 percent were female and 39.39 percent were male; mean age was 25.67± 4.30 years. A total 51 right eyes and 48 left eyes were analyzed. Mean spherical equivalent was -3.30 ± 1.53 diopters. No statistically significant difference was found between the biometric values (axial length, anterior chamber depth and keratometries) obtained with IOL Master 500 versus Pentacam AXL (p > 0.05). Conclusion: Similar biometric measurements (axial length, anterior chamber depth and keratometries) are obtained with IOL Master 500 and Pentacam AXL(AU)
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Humans , Male , Female , Adult , Biometry/methods , Refractive Surgical Procedures/methods , Anterior Chamber/diagnostic imaging , Cross-Sectional StudiesABSTRACT
@#AIM: To compare the differences and agreement in axial length(AL), anterior chamber depth(ACD)flat axial corneal curvature(K1)and steep axial corneal curvature(K2)measured by SW-9000 and IOL Master 500.<p>METHODS: Totally 258 eyes of 129 patients with ametropia were measured with SW-9000 and IOL Master 500. Among them, 159 eyes were low to moderate myopia(-0.75D≤ spherical equivalent <-6D)and 99 eyes were high myopia(spherical equivalent ≥-6D). Comparison between two devices were performed for AL, ACD, K1, and K2. The difference between two instruments were evaluated with a paired samples <i>t</i>-test. The correlation between the measurements was evaluated using Pearson correlation coefficients. The agreement between the devices was evaluated with Bland-Altman plots. <p>RESULTS: There was significant difference between SW-9000 and IOL Master 500 in measuring AL and ACD(all <i>P</i><0.01), but there was no significant difference between K1 and K2 in patients with low to moderate myopia. There was no significant difference in AL, ACD and K1 between SW-9000 and IOL Master 500(all <i>P</i>>0.05), but there was significant difference in K2(<i>P</i><0.05)in patients with high myopia. Pearson correlation analysis showed that AL, ACD, K1 and K2 of patients with low to moderate and high myopia were highly correlated(all <i>P</i><0.01). Bland-Altman consistency analysis showed that the two methods had good consistency in measuring AL in patients with low to moderate and high myopia, but poor consistency in measuring ACD, K1 and K2.<p>CONCLUSION: SW-9000 and IOL Master 500 have good consistency in measuring the AL of people with ametropia. The measurement of ACD and corneal curvature has poor consistency, and should be carefully selected in combination with clinical practice.
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@#AIM: To compare the consistency of IOL Master 700 with IOL Master 500 and A-mode ultrasound for biological measurements, and evaluate the measurements of IOL Master 700 in preoperative examinations of cataract patients. <p>METHODS:In this prospective study, a total of 52 patients(100 eyes)diagnosed as age-related cataract were selected at the Nanjing Medical University Eye Hospital. All the patients were examined in turn by IOL Master 700, IOL Master 500 and A-mode ultrasound. Measurements by these three instruments were compared for axial length(AL), corneal curvature(Km), central anterior chamber depth(ACD), white-to-white(W-W)and pupil diameter(P). The results were analyzed by one-way ANOVA, Pearson correlation and Bland-Altman. <p>RESULTS: The detection rates of AL and ACD with IOL Master 700, IOL Master 500 and A-mode ultrasound were 98%, 87%, 99% and 100%, 99%, 99%; respectively. The detection of Km with IOL Master 700 and IOL Master 500 were 100%, 99%. The detection of W-W and P were both 99%. Among them, 24 eyes had high myopia, posterior scleral grape swelling and axial length ≥26mm. The detection of AL with IOL Master 700, IOL Master 500 and A-mode ultrasound were 96%, 79%, 96%. There was a significant difference in AL and ACD between three instruments(<i>F</i>=11.58, <i>P</i>=0.03; <i>F</i>=12.46, <i>P</i>=0.02). There were no significant differences in Km, W-W and P parameters among three instruments(all <i>P</i>>0.05). The average difference between three instruments for AL measurement: IOL Master 700 and IOL Master 500 was 0.05±0.12mm, IOL Master 700 and A-mode ultrasound was 0.16±0.14mm; The average difference between three instruments for AL measurement in axial length≥26mm: IOL Master 700 and IOL Master 500 was 0.17±0.16mm, IOL Master 700 and A-mode ultrasound was 0.55±0.22mm. The Pearson's correlation analysis showed that there was a high correlation between the measured results of each equipment. The consistency of AL results using Bland-Altman analysis showed there was good consistency in the range of 95% consistency.<p>CONCLUSION: There was high consistency in ocular biological measurements between three instruments in cataract eyes. However, the detection rate of IOL Master 700 in AL was higher than that of IOL Master 500, and the accuracy of the IOL Master 700 measurement was higher in the AL measurement in high myopia with posterior staphyloma. Compared with traditional examination equipment, IOL Master 700 has better penetration and accuracy to provide more accurate measurement parameters.
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@#AIM: To analyze the correlation and consistency of five corneal diameter measurements.<p>METHODS: Totally 25 cases(50 eyes)who underwent ICL implantation in West China Hospital. The preoperative horizontal corneal diameter was measured using measuring caliper, SIRIUS anterior eye assay system, IOL Master500, anterior segment OCT and UBM. <p>RESULTS: The mean WTW distances were 11.54±0.30 mm as obtained with measuring caliper, 11.77±0.33mm with SIRIUS anterior eye assay system, 11.98±0.33mm with IOL Master500, 11.63±0.35mm with anterior segment OCT and 11.53±0.34mm with UBM. No statistical difference was found between measuring caliper and UBM, measuring caliper and anterior segment OCT, UBM and anterior segment OCT. The linear correlation analysis found significant correlation between the measurements of the five measurements. The Bland-Altman analysis for the measuring caliper and SIRIUS, measuring caliper and UBM, measuring caliper and anterior segment OCT found that the absolute values of 95% LOA upper and lower limits were less than 0.5mm.<p>CONCLUSION: The results of the four kinds of corneal horizontal diameter measurements can be interchanged including SIRIUS, UBM, anterior segment OCT and measuring caliper. IOL Master500 results are the largest, that cannot be used as a diagnostic basis for measuring the size of corneal horizontal diameter. The results of other measurement equipment should be combined with clinical practice.