ABSTRACT
The aging changes in tyrosine hydroxylase(TH) -like neurons of the brainstem raphe nuclei in young (2 months), adult(10 months) and old(24 months) rats were examined combining the immunogold-silver staining(IGSS) and the image quanitative analysis. In the raphe nuclei, TH-like neurons were mainly localized in the nucleus raphe dorsalis, nucles centralis superior and nucleus linealis oralis. Number of the neurens in the all nuclei began to be lost significantly from the adult, (?) the old, the number reduced by almost 1/3(P
ABSTRACT
Combining the immunogold-silver staining (IGSS) method with the image quantitative analytical study, changes in somatostatin(SOM)-like, neurons of the hippocampal formation were investigated in young (2 monthes), adult (10 monthes) and old (24 monthes) rats. The results were as follows:1. The number of the SOM-like neurons decreased gradually from the young to the old. Moreover, there was a significant difference among the three age groups (p
ABSTRACT
Changes in SOM-like neurons of the hippocampal formation were investigated inWistar male rats(young-2 months old;adult-10 months old;aged-24 months old)by using the combination of the IGSS method and image quantitative analysis.The following results were obtained:1.Number of SOM-like neurons decreased markedly(P