ABSTRACT
Objective T lymphocyte subsets in children with characteristics observed with infec-tious mononucleosis (infectious mononucleosis,IM),to explore its reference value.Methods January 2011 to December 2014 during a pediatric door altogether 115 cases of hospitalized children were divided in-to three groups,51 cases of IMgroup,33 atypical group,31 patients flyers syndrome,selecting outpatient healthy children as 101 cases the control group.For each group T lymphocyte subsets:CD3 + CD4 +,CD3 +CD8 +,CD4 +/CD8 + ratio,analyze the differences between the groups was significant.Results Compared four groups of T lymphocyte subsets (CD3 +,CD3 +CD4 +,CD3 +CD8 +,CD4 +/CD8 + ratio)change char-acteristics,IMgroup,atypical group,flyers syndrome group and the control group,the difference was sta-tistically significance (P 0.05),two groups of children described in T there was no significant difference in lymphocyte immune.Conclusions T lymphocyte subsets have some reference value in the differential diagnosis of IM,and prompt clinical attention to EB virus infection in chil-dren whose immune function,can help prevent and treat.
ABSTRACT
Objective To approach the clinical characteristics of extrapulmonary complication induced by mycoplasma pneumoniae(MP) infection and infectious mononucleosis syndrome. Methods The MP-IgM(+), EBV- IgM(+) were determined by enzyme- linked immunosorbent assay.There were 18 cases infected with MP and infectous mononucleosis syndrome with abnormal fever,cervix lyphadenectasis,pharyngitis,liver and spleen intumescence,lung infection, and so on.They were analyzed by reviewing.Results There were 8 cases(44.4%) with extrapulmonary complication, among them 3 cases(16.6%) with liver injury,1 case (5.56%) with heart injury,2 cases(11.1%) with both heart and liver injuries,1 case(5.56%) with urinary system injury (nephritis), 1 case (5.56%) with nervous system injury (encephalitis).The complication usually arised 1 week after primary affection, but had no typical clinical symptoms.There was only 1 case with encephalitis who expressed the symptom of nervous system symptom firstly, and was clinically dia- gnosed by assistant examinations. All the cases recovered after 3 weeks′ treatment with macrolides, 5-7 days with ganciclovir, and also with regular complication and support treatments.Conclusions The incidence of extrapulmonary complication induced by MP infection and infectous mononucleosis syndrome is higher than that by the single infection, and its clinical symptom isn′t obvious and is easy to be covered by original illness. And a few showing the extrapulmonary as the first symptom is easily mistakenly diagnosed .As a result, the prognosis is favorable if we make subsidiary inspection and diagnosis as soon as possible and give it with regular treatment.