ABSTRACT
El potencial terapéutico de los probióticos, como agentes capaces de alterar la microbiota intestinal y ofrecer efectos benéficos a la salud, han llevado a su uso en patologías frecuentes en la edad pediátrica, sin embargo los resultados han sido heterogéneos. Se ha descrito una mayor eficacia en la prevención de manifestaciones clínicas de la intolerancia a la lactosa y del cólico del lactante, así como también en la enterocolitis necrotizante, además del mantenimiento de la fase de remisión en colitis ulcerativa. Su eficacia es menor, aunque es recomendable su uso, en el manejo del cólico del lactante. En la actualidad no se recomienda su uso para Enfermedad de Crohn ni tratamiento de la enterocolitis necrotizante. Aunque hay resultados satisfactorios, aún no existen recomendaciones firmes en infección por H. pylori. Todas las recomendaciones deben ser para cepas específicas de probióticos en cada enfermedad.
The therapeutic potential of probiotics, as agents capable of altering the intestinal microbiota and provide beneficial health effects have led to its use in common diseases in children, but the results have been mixed. It seems to be more effective in preventing clinical manifestations of lactose intolerance and prevention of colic and necrotizing enterocolitis, as well as maintenance of remission in ulcerative colitis. Although its effectiveness is lower, it is recommended the use in the management of colic. At present its use for treating Crohn's disease or necrotizing enterocolitis is not recommended. Although there are successful results, there are still no firm recommendations H. pylori infection. All recommendations must be for specific strains of probiotics in each disease.
ABSTRACT
Introdução: A periodontite é um processo inflamatório crônico multifatorial em resposta ao biofilme dental, que pode estar associado à doenças inflamatórias crônicas por ser um foco distante de inflamação sistêmica. Dessa forma, podendo estar associada à doenças intestinais inflamatórias crônicas. Objetivo: Esta revisão literária teve por objetivo compreender e verificar as possíveis evidências da associação entre periodontite e doenças intestinais inflamatórias crônicas. Revisão da literatura: foram buscados e selecionados artigos científicos nas bases Medline/Pubmed que explicassem a associação entre periodontite - e seus fatores associados - e doenças intestinais, tais como Doença de Crohn e Colite Ulcerativa. Conclusão: fica evidente que é possível que exista associação entre periodontite e doenças intestinais inflamatórias crônicas, principalmente quanto a etiopatogenia, a microflora e os fatores de risco. Além disso, a presença simultânea de ambas sugere o agravamento da severidade e da prevalência das mesmas. Apesar disso, até o presente momento, mais estudos são necessários para que se possa afirmar a relação direta dessas doenças.
Introduction: Periodontitis is a multifactorial chronic inflammatory processin response to the biofilm, which may be associated with chronic inflammatory diseases by being a distant focus of systemic inflammation. Thus, may be associated with chronic inflammatory bowel diseases. Objective: This literature review aimed to understand and verify the possible evidence of the association between periodontitis and chronic inflammatory bowel diseases. Literature Review: We searched and selected papers in Medline/Pubmed, to explain the association between periodontitis and its associated factors-and-intestinal diseases such as Crohns Disease and Ulcerative Colitis. Conclusion: It is evident that there may exist an association between periodontitis and chronic inflammatory bowel diseases, particularly regarding the pathogenesis, microflora and the risk factors. Morover, the simultaneous presence of both suggest an increased severity and prevalence thereof. Nevertheless, to date, more studies are needed to affirm the direct relationship between these diseases.
Subject(s)
Humans , Colitis, Ulcerative , Crohn Disease , Inflammatory Bowel Diseases , PeriodontitisABSTRACT
La enfermedad Inflamatoria Intestinal: (Rectocolitis Ulcerosa Idiopática y Enfermedad de Crohn) presenta diferentes características epidemiológicas, endoscópicas e histológicas. Materiales y Métodos: Estudio descriptivo, transversal retrospectivo ? prospectivo, donde se aplicó un formulario desde enero hasta noviembre 2006 para determinar las características epidemiológicas, endoscópicas, e histológicas de los pacientes. Resultados: Se encontró 28 pacientes con Rectocolitis Ulcerosa Idiopatica y 6 pacientes con Enfermedad de Crohn. En RCUI predominó el sexo femenino (53.6%), raza mezclada (92.9%), antecedentes familiares ausentes (78.6%) sin antecedentes personales de importancia (82.1%), con Pancolitis (53.6%) y duración de la enfermedad entre 6 meses y 5 años el (60.8%). En Crohn se presentó similar distribución de sexo, la raza predominante fue la mezclada (83.3%), ningun antecedente familiar, habito tabáquico y localización solo en Colon (50%) y 66.6% tenían menos de 1 año del diagnostico. En Rectocolitis el grupo etáreo mas frecuente (35.7%) de 30 ? 39 años, en Crohn 33.3% en grupos etáreos de 30-39 y 40-49 años. Los síntomas mas frecuentes fueron similares en ambas dolor abdominal y diarrea con o sin sangre. Los hallazgos endoscopicos 53.6% enfermedad moderada con reporte histológico de ulceras, abscesos o distorsión de las criptas 82.4% en rectocolitis y Ulceraciones lineales o serpenginosas en segmentos efectuando recto en 100%, histología de conglomerado de macrófagos (83.3%) y granulomas no caseosos o epiteloides en 66.7% en Crohn. Conclusiones: Los resultados coinciden en su mayoría con los reportados en la literatura internacional y deben servir como base de datos para la realización de estudios prospectivos.
The aim of this study was to determine epidemiologic characteristics, endoscopic and histologic findings of Inflamatory Bowel Disease (IBD): Ulcerative Colitis (UC) and Crohn`s disease (CD) performed in outpatients in the Hospital Universitario de Maracaibo between January and November 2006. Through a descriptive, retrospective-prospective, transversal. study the information was recorded with a cuestionary, 28 pacients had UC and 6 CD, female was most frequent in 53.6%, Hispanic race (92.9%), without any family(78.6%) or personal past history (82.1%). Pancolitis was present in 53.6%. The time of illness was between 6 months to 5 years (60.8%). CD had similar sex distribution, Hispanic race was predominant in 83.3%, no tabaco habit and colon only presentation in 50%. 66.6% had one year or less with the diagnosis. UC was more frequent between 30-39 years of age (35.7%), CD more frequent between 30-39 and 40-49 years of age (33.3%). The most frequent clinical feature was abdominal pain, diarrhea with/ without blood. Endoscopic features were moderate illness 53.6%, with crypt architectural distortion, abscess, and ulcers (82.4%) in UC. CD segmental involment with skip areas, deep linear ulcerations rectum spared 100% and epitheloid granulomas 66.7% and infiltration of macrophages 83.3%. This report was similar in current issue and could be used in prospective studies.