ABSTRACT
Aim: Surface Quick, an alcohol-based solution has been prepared by HELVEMED Company and various advantages have been mentioned for it; however all these claims have not been assessed scientifically. This study evaluated the antifungal efficacy of Surface Quick solution on candida albicans species obtained from the patients with denture-induced candidiasis. Study Design: This is an experimental study for evaluation of antifungal effect of surface quick solution. Place and Duration of Study: This study was done in Oral medicine and microbiology department of Shahid Beheshti University of Medical Sciences, Tehran, Iran in 2012. Methodology: In this experimental in vitro trial, standard Candida albicans species (PTCC 5027) were obtained and the samples were prepared from 30 patients with denture-induced candidiasis using sterilized swab. Candida albicans species were grown in the sabouraud dextrose agar medium and the diameter of the inhibitory zone were calculated after exposing the medium to Surface Quick solution. The difference of inhibitory zone diameter between men and women was statistically analyzed by Student t test and the association of the individuals’ age and gender with inhibitory zone diameter was assessed by logistic regression analysis. Results: The mean and standard deviation of the inhibitory zone diameter after exposing candida albicans species with Surface Quick solution was 10.13 mm and 3.33 mm. No significant differences were found between candida albicans species obtained from the male and female individuals. There was no significant association among participants’ age and gender with the inhibitory zone diameter. Conclusion: According to the results, Surface Quick solution was effective against Candida albicans species obtained from candidacies patients even in the least concentration. Therefore this solution could be used for surface disinfection caused by candida albicans.
ABSTRACT
ColV~+ strains of Escherichia coli produced larger inhibitory zones when these strains grown on nutrient agar containing phosphate after overlaid sensitive indicators. This appears that production of colicin V is increased by the addition of phosphate to nutrient agar. It was sure that stimulation of phosphate to colicin V formation results from its effect in reducing divalent cation levels in nutrient agar since adding EDTA to nutrient agar had the same effect as phosphate, but the addition of Mg~(2+) or Ca~(2+) had the oppsite effect. Therefore nutrient agar supplemented with phosphate can be used to isolate and identificate ColV~+ strains of E. coli.