The Regulatory Status of Functional Foods in the Economic Integration Organizations of Latin America and the Caribbean / El Estatus Regulatorio de los Alimentos Funcionales en las Organizaciones de Integración Económica de Latinoamérica y el Caribe

Introduction. The legal declarations on functional foods of the four main economic integration organizations in Latin America and the Caribbean (LAC) ­ Pacific Alliance (PA), Caribbean Community (CARICOM), Southern Common Market (MERCOSUR) and Central American Integration System (SICA) - are based on the Codex Alimentarius system and do not regulate functional foods. The use of Codex in food marketing is an insufficient condition for its application in functional foods. Regulation based on scientific and technology results are required to be used in the economic integration organizations of LAC. Objective. The objective is to analyze the theoretical framework of the legal foundations that could govern the commercialization processes of functional foods, whose research advances have currently only been manifested in nutritional health. This article also seeks to address this gap through a systematic analysis of international regulations. Materials and methods. For this, a review of the literature emanating from two databases from 2018-2023 is carried by applying the legal-economic research method of documentary content analysis, applied to three general food marketing regulations: food safety declarations, regulations for inspections, food manufacturing and food labeling. Results. The results reveal the absence of specific legislation for functional foods in LAC economic integration organizations. Conclusions. The legal principle of marketing based on peremptory norm (also called jus cogens) can be facilitated through side letters, included in the contents of international contracts. along with the registration requirements of industrial property rights of the member countries associations(AU)

Introducción. Las declaraciones legales sobre alimentos funcionales de las cuatro principales organizaciones de integración económica de América Latina y el Caribe (ALC) ­ Alianza del Pacífico (AP), Comunidad del Caribe (CARICOM), Mercado Común del Sur (MERCOSUR) y Sistema de Integración Centroamericana (SICA) - se basan en el sistema del Codex Alimentarius y no regulan los alimentos funcionales. El uso del Codex en la comercialización de alimentos es condición insuficiente para su aplicación en alimentos funcionales. Se requiere que las regulaciones basadas en resultados científicos y tecnológicos sean utilizadas en los organismos de integración económica de ALC. Objetivo. Analizar el marco teórico de los fundamentos legales que podrían regir los procesos de comercialización de alimentos funcionales, cuyos avances en investigación actualmente solo se han manifestado en salud nutricional. Este artículo también busca abordar esta brecha a través de un análisis sistemático de las regulaciones internacionales. Materiales y métodos. Se realiza una revisión de la literatura emanada de dos bases de datos del período 2018-2023 aplicando el método de investigación jurídico- económica de análisis de contenido documental, aplicado a tres normas generales de comercialización de alimentos: declaraciones de seguridad alimentaria, normas para inspecciones, fabricación de alimentos y etiquetado de alimentos. Resultados. Los resultados revelan la ausencia de legislación específica para alimentos funcionales en las asociaciones comerciales de ALC. Conclusiones. El principio jurídico de comercialización basado en norma imperativa (también llamado jus cogens) puede facilitarse a través de cartas complementarias, incluidas en el contenido de los contratos internacionales. junto con los requisitos de registro de los derechos de propiedad industrial de las asociaciones de los países miembros(AU)

Influence of glyphosate underdoses on the suppression of Panicum maximum cultivars / Subdoses de glifosato na supressão de cultivares de Panicum maximum

The use of herbicide underdoses allows minimizing the competition of grasses on annual crops, enabling simultaneous cultivation. In this context, the objective of this study was to investigate glyphosate underdoses on the suppression of the initial growth of three Panicum maximum cultivars aiming at the integrated cultivation, in addition to the effects of forage species on the incidence and development of weeds. Three field experiments were conducted. The experimental design was a randomized block design with four replications and eight treatments consisting of increasing glyphosate doses (0, 54, 108, 270, 378, 540, 756, and 1,080 g a.e. ha−1). An atrazine dose of 1,200 g a.i. ha−1 was added to each treatment. Plant phytotoxicity assessments were performed at 7, 14, 21, and 28 days after application. At 80 and 125 days after sowing, the assessments of total dry matter production, leaf dry matter, stem dry matter, and leaf to stem ratio were carried out, in addition to density and dry matter production of weed community. Glyphosate underdoses below 215, 65, and 90 g a.e. ha-1 have a potential to be investigated aiming at the management of P. maximum cv. Atlas, P. maximum cv. Mombasa, and P. maximum cv. Tanzania under intercropping. The three forage species are effective in suppressing weeds.(AU)

A utilização de subdoses de herbicidas permite amenizar a competição exercida pelas gramíneas sobre a cultura anual, viabilizando o cultivo simultâneo. Neste contexto, objetivou-se pesquisar subdoses de glifosato na supressão do crescimento inicial de três cultivares de Panicum maximum, almejando o cultivo integrado, além dos efeitos das forrageiras sobre a incidência e o desenvolvimento das plantas daninhas. Foram conduzidos três ensaios em campo. O delineamento experimental utilizado foi em blocos casualizados, com quatro repetições e oito tratamentos, formados por doses crescentes do herbicida glifosato (0; 54; 108; 270; 378; 540; 756 e 1.080 g de e.a. ha-1). Em todos os tratamentos foram adicionados 1.200 g de i.a. ha-1 de atrazine. Foram realizadas avaliações de fitointoxicação de plantas aos 7, 14, 21 e 28 dias após a aplicação. Aos 80 e 125 dias após a semeadura foram realizadas avaliações de produção de matéria seca total, matéria seca de folha, matéria seca de colmos e relação folha: colmo, além da densidade e produção de matéria seca da comunidade de plantas daninhas. Subdoses de glifosato abaixo de 215, 65 e 90 g de e.a. ha-1 possuem potencial para serem pesquisadas visando ao manejo de Panicum maximum cv. Atlas, Panicum maximum cv. Mombaça e Panicum maximum cv. Tanzânia em consórcio. As três forrageiras são eficientes na supressão de plantas daninhas.(AU)

Study on interventions based on urban-rural integration system construc-tion to consolidate achievements of schistosomiasis control in hilly schistoso-miasis endemic areas / 中国血吸虫病防治杂志

Objective To explore the effectiveness of comprehensive schistosomiasis control interventions based on urban-rural integration system construction to carry out the schistosomiasis control in hilly schistosomiasis endemic areas ,so as to offer a new mode to consolidate the achievements of schistosomiasis control in the new situation. Methods Shouan Town and Changqiu Township in Pujiang County in hilly schistosomiasis endemic regions were selected as demonstration areas. The com-prehensive schistosomiasis control interventions based on urban-rural integration system construction were implemented ,includ-ing the land consolidation,centralized residence and so on. The effectiveness the interventions was evaluated. Results In Shouan Town and Changqiu Township,the transformed environments with Oncomelania hupensis snail habitats were 1330.61 hm2 and 1456.84 hm2,the areas with snails decreased from 94.31 hm2 and 83.00 hm2 in 2000 to both 0 in 2015,the positive rates of serological tests for schistosomiasis decreased from 11.8%and 7.53%in 2000 to 1.01%and 1.86%in 2015,and the pos-itive rates of parasitological tests decreased from 0.18%and 0.15%in 2000 to both 0 in 2015 respectively. The numbers of cattle decreased from 358 and 368 in 2000 to 4 and 6 in 2015 respectively. In 2000,the schistosome infection rates of cattle were 3.63%and 6.51%in Shouan Town and Changqiu Township respectively,and from 2004,no infected cattle were found. Conclu-sion The comprehensive schistosomiasis control interventions based on urban-rural integration system construction can de-crease the schistosome infection rate and area with snails effectively,providing a new mode for schistosomiasis elimination.

Reduced Gray Matter Volume of Auditory Cortical and Subcortical Areas in Congenitally Deaf Adolescents: A Voxel-Based Morphometric Study

PURPOSE: Several morphometric studies have been performed to investigate brain abnormalities in congenitally deaf people. But no report exists concerning structural brain abnormalities in congenitally deaf adolescents. We evaluated the regional volume changes in gray matter (GM) using voxel-based morphometry (VBM) in congenitally deaf adolescents. MATERIALS AND METHODS: A VBM8 methodology was applied to the T1-weighted magnetic resonance imaging (MRI) scans of eight congenitally deaf adolescents (mean age, 15.6 years) and nine adolescents with normal hearing. All MRI scans were normalized to a template and then segmented, modulated, and smoothed. Smoothed GM data were tested statistically using analysis of covariance (controlled for age, gender, and intracranial cavity volume). RESULTS: The mean values of age, gender, total volumes of GM, and total intracranial volume did not differ between the two groups. In the auditory centers, the left anterior Heschl's gyrus and both inferior colliculi showed decreased regional GM volume in the congenitally deaf adolescents. The GM volumes of the lingual gyri, nuclei accumbens, and left posterior thalamic reticular nucleus in the midbrain were also decreased. CONCLUSIONS: The results of the present study suggest that early deprivation of auditory stimulation in congenitally deaf adolescents might have caused significant underdevelopment of the auditory cortex (left Heschl's gyrus), subcortical auditory structures (inferior colliculi), auditory gain controllers (nucleus accumbens and thalamic reticular nucleus), and multisensory integration areas (inferior colliculi and lingual gyri). These defects might be related to the absence of general auditory perception, the auditory gating system of thalamocortical transmission, and failure in the maturation of the auditory-to-limbic connection and the auditorysomatosensory-visual interconnection.

A divisão sexual do trabalho no sistema de integração agroindustrial / The sexual division of labor in the agribusiness system of integration

Neste texto mostramos algumas das transformações nas relações de trabalho no setor da agroindústria, ocorridas nas pequenas propriedades familiares rurais, localizadas no oeste catarinense e que são vinculadas ao sistema de integração da Sadia. Analisa particularmente a manutenção da desigual divisão sexual do trabalho na pequena unidade produtiva familiar avícola. Destacamos ainda alguns elementos presentes na divisão sociossexual nesse setor e concluímos indicando alguns desafios para o Serviço Social.

In this text we show some of the tranformatios in the labour relations in the agroindustry sector that ocurred in the small rural family properties, located in the west of Santa Catarina's State and that are vinculated to Sadia's sistem of integration. Analise in particular the maintenance of the unequal sexual division of labour in the small poultry familiar productive unity. We underline yet some elements in the social‑sexual division of labour in this sector and indicate some challenges for the social service.

Produção de cordeiros em pastejo contínuo de azevém anual submetido à adubação nitrogenada / Production of lambs under continuous ryegrass grazing subjected to nitrogen

Neste trabalho, avaliou-se o efeito da adubação nitrogenada do pasto de azevém (Lolium multiflorum Lam.) sobre a produção de cordeiros de corte mantidos em pastejo contínuo. O pasto foi implantado em plantio direto, em área de integração lavoura-pecuária. A adubação de fundação foi realizada com 60kg P2O5 ha-1 e 60kg K²O ha-1. Os tratamentos corresponderam às doses 0; 75; 150 e 225kg de N ha-1, na forma de ureia (45 por cento de N), em cobertura, 35 dias após o plantio. O período de avaliação foi de 84 dias. A oferta de forragem foi influenciada de forma quadrática pelas doses de N, com menor disponibilidade para 182,75kg de N ha-1; no entanto, a oferta de lâminas foliares não foi influenciada pelas doses de N (3,8kg de massa de forragem de folhas/100kg de PV), nem o ganho de peso médio diário, com média 0,133kg de PV an-1 dia-1. Para carga animal e ganho de peso por área as doses de N proporcionaram aumento de 3,0kg de PV ha-1 e 1,1kg de PV ha-1, respectivamente por kg de N aplicado. A adubação nitrogenada proporcionou aumentos na carga animal, o que resulta no aumento de kg de carne produzidos nesse sistema.

It was evaluated the effect of nitrogen fertilization in ryegrass pasture (Lolium multiflorum Lam.) on the production of meat lamb under continuous grazing. Ryegrass pasture was established under no-tillage cropping in area of animal-crop integration system. The fertilization was held with 60kg of P2O5 ha-1 and 60kg of K²O ha-1. The treatments corresponded to the doses 0; 75; 150 e 225kg of N ha-1, in the urea form (45 percent de N) in single application, 35 days after seeding. The evaluation period was of 84 days. The forage was influenced quadratic ally by N rates, with minimum point at 182.75kg of N ha-1. However, the supply of leaf blades (LFM) was not influenced by doses of N (3.8kg LFM 100kg-1 live weight) or by the average daily weight gain, averaging 0.133 kg of LW an day. For stocking rate and live weight gain per area the doses of N increased 3.0 kg of LW-1 ha-1 and 1.1kg of LW ha-1, respectively for each kg of N applied. Nitrogen fertilization provides increases in animal productivity which results in increase kg of meat produced in this system.