Recovery of a patient with severe COVID-19 by acupuncture and Chinese herbal medicine adjuvant to standard care / 中西医结合学报

There is currently no drug or therapy that can cure the coronavirus disease 2019 (COVID-19), which is highly contagious and can be life-threatening in severe cases. Therefore, seeking potential effective therapies is an urgent task. An older female at the Leishenshan Hospital in Wuhan, China, with a severe case of COVID-19 with significant shortness of breath and decrease in peripheral oxygen saturation (SpO

Terapia Comunitária Integrativa em Saúde Mental: Por uma Atenção Dialógica, por um Cuidado Extramuros / Integrative Community Therapy in Mental Health: By a Dialogical Attention and Care Outside the Walls

A partir das contribuições da Reforma Sanitária e Psiquiátrica e com o advento do Sistema Único de Saúde (SUS), uma série de novas tecnologias de saber-fazer saúde emergiram, em um viés universal, integral e com foco na promoção do cuidado. Dentre elas, temos a Terapia Comunitária Integrativa (TCI) como ferramenta oportunizadora de relações interpessoais, da valorização de experiências de vida e de fomento ao empoderamento. Partindo dessas questões, este estudo teve o objetivo de analisar a TCI enquanto dispositivo de promoção do cuidado em Saúde Mental. Trata-se de um relato de experiência, de caráter crítico-interpretativo, que versa sobre a implantação e condução de 26 rodas de TCI em três cenários distintos de um município do Ceará dentro do contexto formativo-pedagógico de programa de Residência em Saúde de instituição pública de ensino do Ceará. O material de base deste estudo foram as participações observantes, as fichas de apreciação das rodas e os diários de campo dos terapeutas comunitários. Os resultados obtidos demonstraram que a TCI contribuiu como uma importante tecnologia de cuidado dentro do contexto da Saúde Mental, sobretudo na perspectiva de uma atenção extramuros direcionada à comunidade na produção de redes de vida.

From the contributions of the Health Reform and Psychiatric and with the advent of the Unified Health System (SUS), ruptures occurred in a number of structural paradigms of health and illness and a host of new technologies to make health emerged in a universal proposition integral and focusing on promotion of care. Among them, we have the Community Integrative Therapy (TCI) as facilitator of interpersonal relationships, valuing life experiences and fomenting empowerment. Based on these questions, this study aimed to analyze the TCI as a device to promote care in Mental Health. This is an experience report, critical-interpretative character about the implantation and conduction of 26 TCI wheels in three different scenarios in a municipality of Ceará within the context of Health Residency program of a public educational institution in Ceará. The base material of this study were observant participation, evaluation sheets and field diaries of community therapists. The results obtained demonstrated that TCI contributed as an important care technology within the context of Mental Health, especially in the perspective of community oriented attention in the production of life networks.

Far infrared-emitting ceramics decrease Freund's adjuvant-induced inflammatory hyperalgesia in mice through cytokine modulation and activation of peripheral inhibitory neuroreceptors / 中西医结合学报

<p><b>OBJECTIVE</b>The present study aimed to evaluate the analgesic and anti-inflammatory effects of far infrared-emitting ceramics (cFIRs) in a model of persistent inflammatory hyperalgesia and to elucidate the possible mechanisms of these effects.</p><p><b>METHODS</b>Mice were injected with complete Freund's adjuvant (CFA) and treated with cFIRs via placement on a pad impregnated with cFIRs on the bottom of the housing unit for different periods of time. Mice underwent mechanical hyperalgesia and edema assessments, and tumor necrosis factor-α (TNF-α), interleukin-1β (IL-1β) and IL-10 levels were measured. Twenty-four hours after CFA injection and 30 min before cFIR treatment, mice were pretreated with a nonselective adenosinergic antagonist, caffeine, the selective adenosine receptor A antagonist, 1,3-dipropyl-8-cyclopentylxanthine (DPCPX), the selective cannabinoid receptor type 1 antagonist, AM281, the selective cannabinoid receptor type 2 antagonist, AM630, or the nonselective opioid receptor antagonist, naloxone, and mechanical hyperalgesia was assessed.</p><p><b>RESULTS</b>cFIRs statistically (P < 0.05) decreased CFA-induced mechanical hyperalgesia ((82.86 ± 5.21)% in control group vs (56.67 ± 9.54)% in cFIR group) and edema ((1699.0 ± 77.8) μm in control group vs (988.7 ± 107.6) μm in cFIR group). cFIRs statistically (P < 0.05) reduced TNF-α ((0.478 ± 0.072) pg/mg of protein in control group vs (0.273 ± 0.055) pg/mg of protein in cFIR group) and IL-1β ((95.81 ± 3.95) pg/mg of protein in control group vs (80.61 ± 4.71) pg/mg of protein in cFIR group) levels and statistically (P < 0.05) increased IL-10 ((18.32 ± 0.78) pg/mg of protein in control group vs (25.89 ± 1.23) pg/mg of protein in cFIR group) levels in post-CFA-injected paws. Peripheral pre-administration of inhibitory neuroreceptor antagonists (caffeine, DPCPX, AM281, AM630 and naloxone) prevented the analgesic effects of cFIRs (P < 0.05).</p><p><b>CONCLUSION</b>These data provide additional support for the use of cFIRs in the treatment of painful inflammatory conditions and contribute to our understanding of the neurobiological mechanisms of the therapeutic effects of cFIRs.</p>

Efeito positivo da técnica de imposição de mãos análoga ao toque quântico sobre o crescimento das radículas de sementes de feijão submetidas ao estresse salino / Positive effect of the laying-on of hands technique analogue to the quantum touch on the radicles growth of bean seeds submitted to salinity stress

Introdução: o biocampo é um tipo de energia sutil emitido pelos organismos vivos que tem a capacidade de influenciar processos biológicos e a homeostase. O biocampo também pode ser definido como sendo o campo eletromagnético endógeno dos corpos de organismos vivos. Objetivo: determinar o efeito da técnica de imposição de mãos análoga ao toque quântico sobre o crescimento de radículas de sementes de feijão (Phaseolus vulgaris) submetidas ao modelo experimental de adoecimento do estresse salino. Método: a amostra de 1600 sementes de feijão foi distribuída equitativamente em quatro grupos: GE1 (sementes expostas ao toque quântico e ao estresse salino), GC1 (sementes submetidas apenas ao estresse salino), GE2 (sementes expostas ao toque quântico, mas não ao estresse salino) e GC2 (sementes não foram submetidas nem ao toque quântico e nem ao estresse salino). Resultado e Discussão: houve diferença significativa entre os comprimentos médios das radículas das sementes dos quatro grupos (ANOVA, F(3, 1303)=255,51, p <0,001). Conclusão: os resultados indicaram que a terapia de biocampo técnica de imposição de mãosanáloga ao toque quântico teve efeito fisiológico significativo sobre o crescimento de radículas de sementes de feijão submetidas ao estresse salino.

Introduction: the biofield is a kind of subtle energy emitted by living organisms that has the ability to influence biological processes and homeostasis. The biofield can also be defined as the endogenous electromagnetic field of the bodies of living organisms. Objective: the purpose of this study was to determine the effect of the laying-on of hands technique analogue to the quantum touch on the radicles growth of bean seeds (Phaseolus vulgaris) submitted to salinity stress. Methods: the sample of 1600 bean seeds was distributed equitably in four groups: GE1 (seeds exposed to quantum touch and salinity stress), GC1 (seeds exposed only to salinity stress), GE2 (seeds exposed quantum touch but not to salinity stress) and GC2 (seeds were not exposed to either quantum touch or salinity stress). Results and Discussion: there was a significant difference between the mean radicles lengths of the seeds of the four groups (ANOVA, F(3, 1303)=255,51, p <0,001). Conclusion: the results indicated that the laying-on of hands technique analogue to the quantum touch had a significant physiological effect on the growth of bean seeds radicles exposed to salinity stress.

Peculiarities of neuropathic pain in children / Peculiaridades da dor neuropática na criança

ABSTRACT BACKGROUND AND OBJECTIVES: In spite of its importance, neuropathic pain is underestimated and undertreated in childhood. Although many conditions causing neuropathic pain in adults are uncommon during childhood, most therapeutic strategies effective for adults were extrapolated for the pediatric population. This study aimed at bringing to light peculiarities of neuropathic pain in children, which shall contribute for its better recognition in childhood and adolescence. CONTENTS: Pubmed, Scielo and Lilacs databases were queried to identify studies and literature reviews on neuropathic pain during childhood and adolescence. CONCLUSION: Neuropathic pain treatment in childhood and adolescence should be multimodal, including pharmacological treatment, rehabilitation and psychological support. Rehabilitation, physiotherapy, occupational therapy and integrative therapies should be part of the integral treatment in childhood and adolescence and vary in a case-by-case basis.

RESUMO JUSTIFICATIVA E OBJETIVOS: Apesar de sua importância a dor neuropática é subestimada e subtratada na infância. Embora muitas das condições que causem dor neuropática no adulto sejam raras na infância; grande parte das estratégias terapêuticas que demonstraram ser eficazes em adultos foi extrapolada para uso na população pediátrica. O objetivo deste artigo foi trazer à luz peculiaridades da dor neuropática na criança, o que contribuirá para seu melhor reconhecimento na infância e adolescência. CONTEÚDO: Foram realizadas buscas nos bancos de dados Pubmed, Scielo e Lilacs, identificando-se estudos e revisões da literatura sobre dor neuropática na infância e adolescência. CONCLUSÃO: O tratamento da dor neuropática na infância e adolescência deve ser multimodal, incluindo tratamento farmacológico, reabilitação e suporte psicológico. Reabilitação, fisioterapia, terapia ocupacional e terapias integrativas devem fazer parte do tratamento integral na infância e adolescência, e variam conforme as necessidades em cada caso.

Clinical Efficacy of Integrative Medicine in Treatment of Nine HIV/AIDS-associated Non-infectious Skin Lesion Cases / 世界科学技术-中医药现代化

This study was aimed to observe the clinical efficacy of Highly Active Antiretroviral Therapy (HAART) combined withPing-Ai(PA) Mixture in the treatment of Human Immunodeficiency Virus / Acquired Immunodeficiency Syndrome (HIV/AIDS) patients with non-infectious skin lesions, in order to study the advantages of integrative medicine in AIDS prevention and treatment. A total of 9 cases, who met the inclusion criteria of AIDS-associated non-infectious skin lesion with the pattern ofqi-yin deficiency and internal obstruction of phlegm-stasis, were selected. The combination of HAART and number 1 and 4 prescription of PA Mixture were used in the treatment for 3 months. The observations were made on changes of clinical symptoms, body signs, Karovsky integral and CD4+ T cells of patients before and after treatment. Stata 12.0 was used in the statistical analysis. The results showed that after integrative therapy, the single integral of clinical symptoms and body signs, such as skin spot papula, subcutaneous nodules, skin itching, fatigue was obviously reduced compared to that of the pretreatment. The total score decreased than that of the pretreatment. The patients’ quality of life (QOL) significantly increased. The Karovsky integral increased compared with that of pretreatment. The CD4+ T cells values were higher than that of the pretreatment. It was concluded that the integrative therapy had a certain effect in the treatment of AIDS-associated non-infectious skin lesions, which can improve the clinical symptoms, body signs, obviously increase the patients’ QOL and immune function.

Evaluation of clinical efficacy of integrative therapy and influencing factors in patients with intractable constipation / 基础医学与临床

Objective To evaluate the effect of integrative therapy and influencing factors in patients with intractable constipation (IC). Methods Eighty-four consecutive IC patients were divided into non overlap and overlap groups. All patients received individualized integrative therapeutic regimen for 4 weeks. The symptom scores of constipation and total effective rates were evaluated. Influencing factor of therapeutic effect in IC was analyzed.Results (1) IC of overlap group and non overlap group accounted for 40.5% (34/84) and 59.5% (50/84), respectively. (2)The total effective rates were 50.0% and 78.0% in overlap and non-overlap group, respectively(P