ABSTRACT
Objective To compare the improvement of peri-orbita rhytides and the patients' satisfaction treated by intense pulse light, Elos and activeFXTM fractional CO2 laser. Methods Two groups of the study were conducted. In first group, 42 volunteers in the hospital were enrolled. All were took photos to evaluate the peri-orbita rhytides by the physician before and one month after activeFX? treatment. Doctors and volunteers evaluated the improvement of peri-orbita rhytides and satisfaction together. In second group, a retrospective study was conducted, in which 40 patients were treated with intense pulse light, and other 40 patients treated with Elos in 2006-2007. Their improvements were analyzed through comparison of their photos before and one month after treatment, and the satisfaction was also evaluated. All data were analysed by SPSS10. 0. Results ActiveFXTM fractional CO2 laser is better than other two techniques for improving peri-orbita rhytides, and patients were more satisfied with this technology. Conclusion The improvement of peri-orbita rhytides and satisfaction treated by activeFXTM is higher than intense pulse light and Elos techniques.
ABSTRACT
Objective To investigate the effects of intense pulsed light(IPL) on the collagen metabolism in human fibroblasts.Methods The callan foreskin fibroblasts were cultured and treated with different wave length and designed dose of IPL irradiation(590-1 200 nm,and 29 J/cm2),while 10 without IPL irradiation as controls.By culturing 1,12,24 and 48 h after the irradiation,the synthesis of collagen was measured by 3H-proline incorporation determination. Results The synthesis of collagen activity increased significantly(P
ABSTRACT
Objective To investigate the effects of intense pulse light(IPL)on the content of colla- gens and mRNA expression of procollagen in BALB/c mouse skin.Methods The BALB/c mice dorsal skin was irradiated by IPL.Skin specimens were taken at different time points after irradiation.Histopatho- logical changes were observed by hematoxylin-eosin-staining,quantitative assessment of collagenⅠand collagenⅢwas performed with immunohistochemical staining,and mRNA expression levels of procollagen were de- tected by RT-PCR.Results After the irradiation,no obvious change was observed for the staining intensity of collegen at 1 week;however,the thickening of dermis began at 2 week,and continued until 8 week.The staining of collagenⅠandⅢwas also stronger in IPL-irradiated regions than in sham-irradiated areas at 2 week(P