ABSTRACT
Appetite is a physiological and psychological factor that governs food intake and food selection. It is regulated by central nerve nuclei, transmitters, peripheral receptors and appetite related factors. Food addiction(FA) and diabetes are related physiologically and pathologically, and are reciprocal independent risk factors. According to research, food addiction is categorized within the subgroup of metabolic diseases such as obesity and diabetes and is regulated by the mesolimbic dopamine system in the brain, driving extreme hedonic overeating behavior. Food addiction is closely associated with genetic and environmental factors. Many products of intestinal flora metabolism are also involved in the occurrence and development of food addiction. In turn, food addiction also causes changes in intestinal flora metabolites. This article focuses on the correlation between intestinal microbial metabolites and food addiction in diabetic patients.