A Case of Intra-epidermal Epithelioma with Clonal Seborrheic Keratosis and Intra-epidermal Eccrine Poroma Differentiation / 대한피부과학회지

Intra-epidermal epithelioma is a rare cutaneous neoplasm and generally used as a histologic description for superficial tumors in which nests are found in well-defined islands within the epidermis. The intra-epidermal nests are composed of keratinocytes, and basaloid or squamoid or pleomorphic cells. Some authors reported that this tumor may be considered an invasion of the epidermis from a malignant tumor and it has the potential of carcinomatous invasion. Herein, we report a case of intra-epidermal epithelioma that showed clonal seborrheic keratosis and intra-epidermal eccrine poroma differentiation on the right thigh areaof a 77-year-old female. Although intra-epidermal epithelioma shows benign features, it may be predisposed to other tumoral changes, such as eccrine poroma, eccrine porocarcinoma, and Bowen's disease. We suggest that individuals with intra-epidermal epithelioma require continuous monitoring of skin changes, including enlargement of size, inflammation, ulceration, and hemorrhages.

A Case of Intraepidermal Epithelioma Showing Dermal Invasion / 대한피부과학회지

Intraepidermal epithelioma is a rare cutaneous neoplasm characterized histologically by intraepidermal collections of malignant appearing keratinocytes preserving the epidermal architecture. In our case, the tumour unusually showed parakeratosis and dermal invasion. There were a few reports which exhibited parakeratosis and invasion. So, we suggest there may be correlation between these factors.

A Case of Intraepidermal Epithelioma / 대한피부과학회지

It has been in dispute for a long time whether so called "intraepidermal epithelioma of Borst-Jadassohn" in which epithelial cells proliferate and form nests in the epidermis, is a distinct pathologic entity or not. We report a case diagnosed nothing but intraepidermal epithelioma.