ABSTRACT
@#AIM: To explore the effect of different intraocular irrigating solutions on lens opacity after pars plana vitrectomy(PPV)for proliferative diabetic retinopathy(PDR).<p>METHODS: Totally 48 subjects(48 eyes)patients with proliferative diabetic retinopathy from March 2018 to February 2019 were enrolled in this study, randomly divided into BSS intraocular irrigating solution group(23 cases and 23 eyes)and Shike intraocular irrigating solution group(25 cases and 25 eyes). LOCS grading system Ⅲ was applied to grade lens opacity. Pentacam occipital analyzer was applied to analyze the density and thickness of lens, and the results were compared and discussed.<p>RESULTS:Three months after PPV,NC, P score and the density of lens in LOCSIII grade in the two groups were significantly higher than those before surgery(<i>P</i><0.05), but the C score was not different significantly(<i>P</i>>0.05). In addition, the thickness of the lens in BSS intraocular irrigating solution group was significantly higher than that before PPV(<i>P</i><0.05), but there was no significant difference in the Shike intraocular irrigating solution group(<i>P</i>>0.05). NC, P score, the density and thickness of lens were significantly lower in Shike intraocular irrigating solution group than those in the BSS intraocular irrigating solution group. But the C score was not different significantly between the two groups(<i>P</i>>0.05).<p>CONCLUSION: Shike intraocular irrigating solution can delay the development of postoperative complicated cataract formation.
ABSTRACT
Objective:To investigate whether topical hypothermia circumstance has the protective effects to the blood-ocular barriers during intraocular operations.Methods:Twenty New Zealand albino rabbits accepted vitrectomy in both eyes,useing hypothermal(4-10℃) intraocular irrigating solution in left eye(hypothermal intraocular irrigating solution group),and useing room temperature(25℃) intraocular irrigating solution in right eye(room temperature intraocular irrigating solution group)during the vitrectomy.Twenty-four hours after the operation,the retina of both eyes were checked;each eye accepted cavum vitreum perforation,and 0.5 ml of intraocular fluid were aspirsted for biochemical detection as well;as well as the retinas cut off for transmission electron microscopical(TEM) observations. Results:Inflammatory reaction of anterior ocular and the uvea in left eyes were generally slighter than the right eyes;dioptric media clarity of left eyes were also better than that in left eyes;average total protein concentration of the intraocular fluid was obviously lower than that in left eye(P