ABSTRACT
Objective To study the chemical constituents from the roots of Glycyrrhiza glabra. Methods Compounds were separated and purified by silica gel and preparative HPLC. The structures were identified by physicochemical properties and spectral analyses. Results Ten isoflavanes were isolated and identified as glabrene T (1), glabridin (2), glyasperin C (3), licoricidin (4), isolicoflavonol (5), licoisoflavone A (6), licoisoflavone B (7), semilicoisoflavone B (8), formononetin (9), and liquiritigenin (10), respectively. Conclusion Compound 1 is a new isoflavane. Compounds 3-6 are isolated from this plant for the first time.
ABSTRACT
Objective: To study the chemical constituents from the stem barks of Engelhardtia roxburghiana. Methods: The compounds were isolated and purified by various chromatographic techniques and their structures were elucidated by spectral analysis. Results: Ten compounds were obtained and identified as eudesm-4(15)-ene-1β, 6α-diol (1), (4S)-4-hydroxy-1-tetralone (2), (-)- regiolone (3), p-hydroxybenzoic acid (4), kaempferol (5), isolicoflavonol (6), broussoflavonol F (7), broussonol E (8), kaempferol-3-O- α-L-rhamnoside (9), and quercetin-3-O-α-L-rhamnoside (10). Conclusion: Compounds 1, 4, and 6-8 are isolated from the plants of Engelhardtia Leschen. et Bl. for the first time, and the prenylated flavonoids are firstly reported in this genus.