ABSTRACT
OBJECTIVE: To study the antibacterial, trichomonacidal, and itching-relieving activities of Hemorrhoids lotion. METHODS: The antibacterial and trichomonacidal activities were detected by serial dilution of liquid medium and trichomonas vaginalis inhibition test in vitro, respectively. The itching-relieving effect of the lotion was observed by using histamine to induce itching of guinea pig. RESULTS: Hemorrhoids lotion inhibited the growth of SA(staphylococcus aureus), aeruginosus bacillus,escherichia coli and blastomyces albicans, and it had trichomonacidal activity on trichomonas vaginalis; furthermore, it increased the threshold value of histamine-induced itching in guinea pig. CONCLUSION: Hemorrhoids Lotion had antibacterial, trichomonacidal, and itching-relieving activities.