Determination of lanthanum in whole blood by microwave digestion-inductively coupled plasma optical emission spectrometry / 药学实践杂志

Objective To evaluate the transdermal safety of lanthanum (La) in sunscreen and jellyfish sting protective lotion, establish a microwave digestion-inductively coupled plasma opticalemission spectroscopy (ICP-OES) method for determination of lanthanum (La) in rat’s whole blood. Methods The whole blood samples were digested by microwave and analyzed by inductively coupled plasma emission spectrometer (ICP-OES). Using 333.749 nm as the analysis line, the content of La in rat whole blood was determined. Results The correlation linearity of the standard curve of this method was good (r>0.9994), the detection limit of the method was 0.0025 μg/ml, the limit of quantification was 0.0077 μg/ml, the precision was less than 3%, and the recovery rate was between 94.9% and 102.0%. Conclusion The ICP-OES method based on microwave digestion is stable and reliable, and can provide an important basis for the study of the transdermal safety of lanthanum.

A Case of Jellyfish Stings Contracted in Korean Coastline / 대한피부과학회지

Untill now occasional cases of jellyfish stings have been reported in Korean literatures but all of the reported patients contracted the stings abroad out of the country. Recently we have found a case of the jellyfish stings first in Korean coastline. The patient was an 11-year-old girl, who got the sting while she was swimming in the southern west coast of the country. The initial skin lesions showed typically whipped appearance and subsided in a month after taking both courses of the immediate toxic reaction and the late allergic reaction. Considering the ecological changes of the sea waters of the Korea, we think the jellyfish stings would occur more frequently also in the country and dermatologists should be familiar with the dermatitis.

Jellyfish Sting / 대한피부과학회지

Stings due to jellyfish, sea anemones, and corals are the most common envenomations encountered with humans in the marine environment. The first case was a 36-year-old female who presented with multiple whiplike linear, dark reddish bullous eruptions on the right forearm after she was stung by a jellyfish in the Philippines 15 days previously. The patient was treated with oral antibiotics for 10 days, but severe pruritus persisted and new papular lesions developed on her hand. Antibiotic therapy was discontinued and oral and topical corticosteroid therapy was applied instead. The skin lesions disappeared without recurrence after about 4 weeks. The second case was a 29-year-old male who visited our department with linear, reddish patches and necrotizing blisters on both the arms, left thigh, and trunk after he was stung by a jellyfish in Thailand. We treated him with oral and topical corticosteroids for 10 days and the lesions cleared. We describe two typical cases of jellyfish sting that are rare in Korea.