ABSTRACT
PURPOSE: A new inhomogeneity correction method based on two-point Dixon sequence is proposed to obtain water and fat images at 0.35T, low field magnetic resonance imaging (MRI) system. MATERIALS AND METHODS: Joint phase-magnitude density function (JPMF) is obtained from the in-phase and out-of-phase images by the two-point Dixon method. The range of the water signal is adjusted from the JPMF, and 3D inhomogeneity map is obtained from the phase of corresponding water volume. The 3D inhomogeneity map is used to correct the inhomogeneity field iteratively. RESULTS: The proposed water-fat imaging method was successfully applied to various organs. The proposed 3D inhomogeneity correction algorithm provides good performances in overall multi-slice images. CONCLUSION: The proposed water-fat separation method using JPMF is robust to field inhomogeneity. Three dimensional inhomogeneity map and the iterative inhomogeneity correction algorithm improve water and fat imaging substantially.