ABSTRACT
A partir del caso de una paciente con síndrome de intestino irritable a predominio de estreñimiento cuyos síntomas mejoraron con el consumo regular de kiwi, el médico de familia se planteó la pregunta de si el kiwi podría mejorar los síntomas asociados a constipación crónica en comparación con el tratamiento habitual. Tras realizar una búsqueda de estudios que analizaran los efectos del consumo de kiwi sobre el hábito intestinal, fueron seleccionados tres artículos que permiten concluir que el consumo de esta fruta tiene una eficacia superior al placebo y comparable al psyllium y las pasas de ciruela para mejorar los síntomas de personas con estreñimiento crónico. (AU)
Based on the case of a patient with constipation-predominant irritable bowel syndrome whose symptoms improved with regular consumption of kiwi, the family doctor wondered if kiwi could improve symptoms associated with chronic constipation compared to usual treatment. After conducting a search for studies that analyzed the effects of kiwi consumption on intestinal habit, three articles were selected that allow us to conclude that the consumption of this fruit has an efficacy superior to placebo and comparable to psyllium and plum raisins to improve the symptoms of people with chronic constipation. (AU)
Subject(s)
Humans , Female , Middle Aged , Constipation/diet therapy , Irritable Bowel Syndrome/diet therapy , Fruit , Psyllium/therapeutic use , Abdominal Pain/diet therapy , Randomized Controlled Trials as Topic , Constipation/diagnosis , Actinidia , Irritable Bowel Syndrome/diagnosis , Feces , Systematic Reviews as TopicABSTRACT
AIM: To observe the effects of superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), myeloperoxidase (MPO) and transforming growth factor-β1 (TGF-β1) of radiation-induced lung injury rats by Kiwi fruit essence (unsaturated fatty acid of actinidia chinesis planch seed oil). METHODS: According to random number table, 90 Sprague-Dawley rats were divided into the control group, model group, 60 mg/kg unsaturated fatty acid of actinidia chinesis planch seed oil intervention group, 120 mg/kg unsaturated fatty acid of actinidia chinesis planch seed oil intervention group, 240 mg/kg unsaturated fatty acid of actinidia chinesis planch seed oil intervention group, 18 animals were included in each group. Except for the control group, rats in the remaining groups were constructed by 6MV-X-ray 18Gy full chest radiation, one week before modeling, the rats in the last 3 groups were given (60, 120, 240) mg/kg unsaturated fatty acid of actinidia chinesis planch seed oil. The first two groups were given 0.9% sodium chloride solution by gavage, once a day in each rat. 14 days, 28 days, and 56 days after radiation, the rats were randomly sacrificed and their chests were cut, and ave lung tissue was saved. HE and Masson staining were performed to observe the pathological changes, and the content of SOD, GSH-Px, MPO was determined. The expression of TGF-β1 was analyzed by immunohistochemical staining. RESULTS: Compared with the model group, (60, 120, 240) mg/kg unsaturated fatty acid of actinidia chinesis planch seed oil significantly reduced the degree of lung alveolitis and radiation pulmonary fibrosis, reduced the content of hydroxyproline (HYP), MPO, increased the antioxidant enzymes SOD and GSH-Px content, down-regulated the expression of TGF-β1.There were significant differences in the above-mentioned indicators among the intervention groups of (60, 120, 240) mg/kg unsaturated fatty acid of actinidia chinesis planch seed oil group, and it was positively correlated with dosage. CONCLUSION: Unsaturated fatty acid of actinidia chinesis planch seed oil has a preventive effect on radiation-induced lung injury, and its mechanism may be related to the reduction of oxidative stress damage and down-regulation of TGF-β1 expression.
ABSTRACT
El síndrome de enterocolitis inducida por proteínas alimentarias es una alergia alimentaria no mediada por inmunoglobulina E que se manifiesta clínicamente con vómitos profusos y repetitivos, en ocasiones, asociados a diarrea, y puede llegar a asociar deshidratación y letargia, con riesgo de desarrollo de shock. A pesar de su potencial gravedad, el índice de sospecha de este síndrome es bajo, lo que demora su diagnóstico, especialmente, en aquellos casos que son desencadenados por alimentos sólidos. La presencia de vómitos y la duración de más de un minuto son los datos clave que pueden diferenciarlo de los episodios breves, resueltos e inexplicados. Se presenta el caso de una lactante de 6 meses de vida con diagnóstico final de síndrome de enterocolitis inducida por proteínas alimentarias por ingesta de kiwi.
Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE food allergy manifesting as profuse, repetitive vomiting, sometimes with diarrhea, leading to dehydration and lethargy that can be severe and lead to shock. Despite the potential severity, awareness of FPIES is low and diagnosis is often delayed, especially in those triggered by solid foods. Presence of vomits and duration of more than 1 minute are the key differential factors to distinguish FPIES from brief resolved unexplained events. We report a case of a 6-month-old infant finally diagnosed as having kiwi induced FPIES.
Subject(s)
Humans , Infant , Vomiting , Dietary Proteins , Actinidia , Enterocolitis , HypersensitivityABSTRACT
OBJECTIVE: To study the chemical constituents of the antioxidant active sites and establish the determination method of the total content of phenolic acid in Actinidia chinensis Planch. seeds. METHODS: AB-8 macroporous adsorption resin, silica gel and ultra performance liquid chromatography-mass spectrometry (UPLC-MS/MS) were used to separate and purify the compounds, and the compounds were identified according to the properties and spectral data of the compounds. The total content of phenolic acid was determined by the spectrophotometry. To establish a method for determination of total content of phenolic acid using ferulic acid as a positive control and ferric chloride-potassium ferricyanide solution as a color developer and methodological investigation was carried out. RESULTS: Twelve compounds were isolated and identified from the active parts of Actinidia chinensis Planch. seeds, which were protocatechuic acid (1), vanillic acid (2), syringic acid (3), protocatechuic aldehyde (4), 3,4-dihydroxyace to phenone. ethyl ketone (5), dihydroconiferyl alcohol (6), 4, 4-dihydroxydiphenylmethane (7), shikimic acid (8), ferulic acid (9), 3-acetoxymethyl-4-methoxy methyl benzoate (10), bis(4-methoxyphenyl) methane (11), and methyl caffeate (12). The total content of phenolic acid in kiwifruit seeds was determined by ultraviolet spectrophotometry. The linear range of the method was 1.6-16 μg•mL-1. The regression equation is Y=0.087 8x+0.045 8, r2=0.999 3, the average recovery is 99.36%, and the RSD is 2.869 9%.The total content of phenolic acid in the total extract was 6.61%, and the active site was 42.46%. The total content of phenolic acid in the active site is about 7 times that of the total extract. It can be seen from the results that the extraction process can effectively enrich the phenolic acid compounds. CONCLUSION: Compounds 5-7 and 10-12 are isolated from the plant for the first time. The determination method of total content of phenolic acid is simple, fast, stable and reproducible, which provides a scientific basis for the systematic study of phenolic acid compounds in kiwifruit seeds.
ABSTRACT
The present study was carried out to find the effect of fruit harvesting stage (October, November and December) on the physicochemical and antioxidant properties in five kiwi cultivars (Abbot, Bruno, Allison, Hayward, Monty). Results showed that soluble solid content (SSC) and pH increased while ascorbic acid (Vit C), titrated acidity (TAD) and SSC/TAD decreased in all the cultivars with delay in harvesting. Total polyphenols (TP) were decreased while total flavonoids (TF) increased in all tested cultivars with delay in harvesting. The highest concentration of TP (2.02 mg gallic acid equivalent/g fresh weight) and TF (51.12 mg catechin equivalent/100g FW) were found in cultivar 'Allison' in the month of October and December, respectively. Antioxidant activities (AA) were genotype depended and no trend was observed with month of harvesting. Principal component analysis (PCA) showed strong correlation between Vit C, TP and antioxidant activities. Two major clusters were computed using agglomerative hierarchical clustering (AHC). All the studied important traits may be used in the breeding programmes to increase the variability for different physiochemical and antioxidative characteristics and to make suitable selections that could be acceptable to consumers.
ABSTRACT
PURPOSE: Kiwi fruit allergy in children has scarcely been reported. This study focused on the clinical characteristics of kiwi fruit allergy and value of kiwi specific Immunoglobulin E (IgE) antibodies in Korean children. METHODS: The study was based on a data analysis of 18 patients, who were diagnosed with clinical kiwi fruit allergy at Ajou University Hospital from June 2005 to June 2012. Clinical details were collected by medical history and telephone survey. Sera from all children were analyzed for kiwi specific IgE (ImmunoCAP) and patients with negative result were further evaluated by an enzyme linked immunosorbentassay test (ELISA) using our own made kiwi fruit extracts. RESULTS: The subjects were 10 male and 8 female with a median aged 25 months. Twelve out of 18 (66.7%) were diagnosed with angioedema or urticaria, 4 (22.2%) were diagnosed with oral allergy syndrome, 1 was presented with dyspnea, and 1 was diagnosed with anaphylaxis. Oral route of exposure (88.9%) was most common and majority of patients (88.9%) experienced clinical symptoms at the first exposure to kiwi fruit. Six out of 12 patients with urticaria showed negative result in specific IgE by ImmunoCAP, but specific IgE were detected in 2 of 6 by ELISA with our own made kiwi extract. CONCLUSION: Systemic reactions to kiwi fruit were common in Korean children, and the symptoms were frequently developed at the first time of exposure. Additional diagnostic methods would be needed for evaluation of IgE sensitization in kiwi allergic patients with negative result by ImmunoCAP.
Subject(s)
Aged , Child , Female , Humans , Male , Anaphylaxis , Angioedema , Antibodies , Dyspnea , Enzyme-Linked Immunosorbent Assay , Fruit , Hypersensitivity , Immunoglobulin E , Immunoglobulins , Statistics as Topic , Telephone , UrticariaABSTRACT
The kiwi (Actinidia deliciosa) is well known to contain anti-oxidants. In this study, we investigated the anti-oxidant effects of kiwi extract on carbon tetrachloride (CCl4) induced liver injury in BALB/c mice. The radical scavenging effect of 80% methanol extract of Halla-Gold kiwi was observed. For the animal study, mice were randomly divided into four groups: normal group, CCl4-induced model group, kiwi extract administered group, and silymarin treated group. The kiwi extract was provided daily for 10 days. At the 24 h after last administration, CCl4 was injected. The kiwi extract showed strong inhibitory effect of DPPH radicals and superoxide scavenging. In animal study, administration of CCl4 resulted in significantly elevated plasma levels of ALT and AST but they decreased in kiwi-extract pretreated group. Anti-oxidant enzymes such as GSH-px and GSH-rd were restored in the kiwi extract treatment group. Histopathological degeneration was also prevented in the kiwi extract treated group compared with of the control group, which exhibited CCl4-induced hepatotoxicity. On the basis of the obtained results, it can be concluded that kiwi extract showed protective effects, not only as anti-oxidant effects, but also in the protection of hepatotoxicity in CCl4-intoxicated mice.
Subject(s)
Animals , Mice , Antioxidants , Carbon , Carbon Tetrachloride , Cytochrome P-450 CYP2E1 , Fruit , Liver , Methanol , Plasma , Silymarin , SuperoxidesABSTRACT
Fresh kiwi fruit freeze-dried juice has been traditionally used for constipation of elderly patients. Its effectiveness and safety was studied in 42 elderly patients (age 60–84: median age 67±6) suffering from mild to moderate constipation, taken as a food supplement of 6 capsules/3 times per day for 4 weeks following a one week control period, after receiving written informed consent. Bowel habits and generic quality of life questionnaires were monitored. Bowel habits such as evacuation time and stool quality improved from the 14<sup>th</sup> day and continued for 28 days compared to the control period.<br> Quality of life in terms of external appearance (such as skin and edema), lumbago, and headache improved. In conclusion, freeze-dried fresh kiwi fruit juice had a laxative and QOL-improving effect on the elderly. No apparent adverse effects were observed.<br>
ABSTRACT
Dentre as fruteiras cultivadas no Brasil, o kiwi, recentemente introduzido, vem alcançando destaque. É planta de clima temperado e possui boa adaptação a climas amenos, apresentando cultivares com pouca exigência em frio invernal, que permite seu cultivo nas regiões Sul e Sudeste. Apresenta restrições de cultivo em locais com deficiências hídricas e com predominância de ventos fortes, sendo indispensável o uso de quebra-ventos para proteção. O presente trabalho divulga informações técnicas sobre seus hábitos de crescimento e frutificação, exigências edafoel-imáticas, cultivares e manejo do pomar. São descritos também, métodos de propagação mais usuais, pragas e doenças com prováveis possibilidades de ocorrência nas condições do Sul do Brasil e manejo pós-colheita.
Among the fruit-trees cultivated in Brazil, the kiwifruit, recently introduced, has increased its importance. It's a temperate climate fruit and has a good aclimatation in mild climate. Cultivars with low cold hibernal requirements allowing its cultivation in Brazil Southern and South-east regions. Its cultivation has restrictions in places with water deficits and with intense winds. This paper reports technical informations about kiwifruit growth, requirements of soil and climate conditions and cultivars and orchard management. It also deseribes propagation methods, pests and diseases that may occur in the region and postharvest handling.
ABSTRACT
1. Anti-mutagenicity testing consists of Ames test (Salmonella/microsome test) and micronucleus test.The research results indicated that Kiwi Sports Drink possesses antimutagenesis. 2. To observe the effects of Kiwi Sports Drink on individuals living in the area of high incidence oflung cancer. We chose seven bank staffs dwelling in the polluted area for more than five years without smo-king habits or chemical occupation exposure as subjects, their mean SCE per cell and urinary BaP were 10.51+0.99 and 0.0027-0.0066 ug/L respectively. Kiwi Sports Drink wers supplemented to them (710 ml dailyper subject for 5 days). After supplementation, SCE per cell decreased to 8.06+1.48, and urinary BaP to