ABSTRACT
Osteoarthritis (OA) of the knee significantly disrupts daily activities and reduces quality of life due to pain. The primary treatment involves anti-inflammatories, which can cause stomach issues. Alternative therapies, including glucosamine, chondroitin, chitosan, and phytoestrogens, are being explored, but their effects need further study. While some benefits may be due to the placebo effect, researchers conducted a literature review to determine their actual benefits. A review of seven meta-analyses found that glucosamine and chondroitin can alleviate pain, reduce stiffness, improve function, and reduce joint space narrowing (JSN) in OA patients. Chitosan's use in intra-articular injections for OA has been studied in four observational studies and clinical trials on animals, but the effects of oral chitosan supplements remain unknown. A literature review on phytoestrogens in OA, particularly in post-menopausal women, identified four relevant studies. The review suggests that glucosamine, chondroitin, chitosan, and phytoestrogens have significant therapeutic benefits for OA, such as reducing pain (measured by VAS score), relieving stiffness, and improving functionality due to their anti-inflammatory and chondroprotective effects. Therefore, additional randomized controlled trials are needed to confirm their effectiveness in managing knee OA.
ABSTRACT
Osteoarthritis (OA), one of the top five most incapacitating conditions that affects more than one third of those over 65, is a degenerative joint disease characterised by joint inflammation and a reparative bone response. OA is a complete joint disease that affects joint ligaments, cartilage, menisci, and muscles that are connected to the joints due to various pathophysiological processes. It is essential to develop a treatment plan that take into account the physiology of degenerative joint disease, but it should also take into account the demands of the various age groups and populations.The multi structural physical, physiological and functional deficits caused by the disease call for the development of physiotherapy. The current study's goal is to assess the effectiveness of progressive resistance exercises, passive stretching exercises, soft tissue manipulation (MET), Maitland mobilisation, aerobic exercises, Tai chi, strength training, balneotherapy and aquatic therapy that are planned, therapist supervised and patient educated.A convenience sample size of 100 was used for the initial investigation. The samples were divided into two study groups at random. BATS were the first interventional group, while PEPSMAN was the second. The interventional group's treatment plan included a physiotherapy routine that was monitored by a therapist.The visual analogue scale, the modified WOMAC scale, the time up and go test, the functional reach test, the 40 meter fast paced walk test, the stair climbing test and the 30 second chair stand test were the outcome variables examined.The majority of analysed end measures showed a significant improvement in the PEPSMAN interventional groups and as a result, the planned supervised physiotherapy protocol was determined to be effective in treating the many physiological deficits linked to the whole joint illness.Anemia is a major public health problem affecting both the developed as well as the developing countries. According to World Health Organization (WHO), prevalence of anaemia among pregnant women is 56% in the developing world. India has the highest prevalence of anaemia and 20% of total maternal deaths are due to anemia. According to NFHS-5 data the prevalence of anemia in rural area of Bihar is 63.9%.
ABSTRACT
Background:Knee osteoarthritis (OA) damages the proprioceptors within the joint cavity which in turn may lead to impairment of balance, an integral part of mobility.Fears and beliefs about knee osteoarthritis in patients with knee osteoarthritis are found to have an adverse impact on their function. Objectives:The study aimed to evaluate the correlation between fearsand beliefs about knee osteoarthritis and balance in patientswith Knee OA. Material andMethods:In an observational analytical study males and females with OA knee were included. Fears and beliefs wereassesse d usingthe Knee Osteoarthritis Fears and Beliefs Questionnaire (KOFBeQ), balancewas tested using the Functional Reach Test (FRT) and pain was assessed by Visual Analogue Scale (VAS).Result:Forty-six patients were evaluated. Mean pain scorewas 4±1.5, FRT score 8.7±2.4inches, KOFBeq score33 ±13.8. Correlation was found using Spearman coefficient, r=0.178, p=0.23(balance and KOFBeq), r=-0.264, p=0.7 (pain and balance), r=-0.3, p=0.018(pain and KOFBeq) was seen.Conclusion:Fears and beliefs about knee osteoarthritis were present with impaired functional balance. Weaknegative correlationwas found between pain and balance and pain and fears and beliefs and no correlation were found between balance and fearsand beliefs.
ABSTRACT
Aim: This study is designed to determine better intervention strategies between pain coping strategies and kinesthesia, balance and agility exercises for chronic knee OA. Study design: Experimental study, Randomized Clinical Trial. Method: 40 participants both male and female with physician diagnosed chronic knee OA were assigned into two groups. The objective of the study was explained, and the subjects were screened based on the inclusion and exclusion criteria. Group A received kinesthesia, balance and agility exercises which include- Wedding march, Backward wedding march, Side stepping, tandem walk, toe walking, heel walking and then exercises progress into leaning forward, backward and sideways, rocker bottom balance board, carioca cross over maneuver and modified grapevine. Group B received Pain coping strategies involving 10 supervised sessions. Both the groups received treatment protocol of 6 weeks with sessions 3 times / week. WOMAC scores were taken at baseline as well as after 6 week of treatment. Results: Both the groups showed clinically and statistically significant improvement in WOMAC scores at the end of 6-weeks of treatment session. i.e., 47.043±11.753 to 5.815±11.079 in group A and 44.579±8.045 to 27.849±5.216 in group B. Conclusion: A significant improvement were observed in both the groups; however the study has demonstrated that KBA exercises presented more beneficial effects in reduction of pain and improvement of functional status whereas pain coping strategies had beneficiary effects in cognitive and behavioral reactions to pain as they affect pain, functional capacity and psychological functioning.
ABSTRACT
The present study aimed to evaluate the effect of the adjuvant use of resveratrol with meloxicam on the clinical scores of knee OA patients. This was a double-blind placebo-controlled randomised trial involving 100 patients with knee osteoarthritis performed at the Shar Teaching Hospital, Sulaimani General Hospital and Specialised Rheumatology Center, Sulaimani City from December 2016 to September 2017. The efficacy of the treatment was evaluated by measuring the changes from baseline in the KOOS score, WOMAC index, and VAS-100 score after 90 days of treatment. Resveratrol significantly improves the knee OA pain and associated symptoms compared with placebo, and both clinical scores were found to be eligible for following treatment outcomes. In conclusion, resveratrol, when used in combination with meloxicam, improves pain and symptom scores in patients with mild-to-moderate knee OA compared with placebo. The intervention with a dietary supplement may significantly impact the pain and overall quality of life in patients with knee OA.