ABSTRACT
Objective To observe the effect of nursing intervention on children with hepatitis C receiving Kurorinone treatment.Methods 98 cases of children patients with hepatitis C admired from February 2008 to May 2010 were randomly divided into the intervention group (50 patients)and the control group(48 patients),all patients were treated with kurorinone for 3 months (one course of treatment),besides the intervention group received additional nursing.The liver function and serum HCV-RNA changes were compared between the two groups.Results Recovery of liver function in the intervention group was significantly better,negative rate of HCV-RNA in the intervention group was significantly higher than that of the control group.Conclusions Nursing intervention can improve treatment effect of kurorinone for children with hepatitis C.
ABSTRACT
Objective To explore the effects of kurorinone on the serum level of TNF-? and IL-6 in the patients with chronic hepatitis B (CHB). Methods 87 patients with CHB were randomly divided into groups A and B. Patients in group A (n=45) and group B (n=42) received kurorinone and diammonium glycyrrhizin treatment, respectively, for 3 months. The liver histopathological changes were observed, and liver function and the serum level of TNF-? and IL-6 in the patients with CHB were detected after treatment. Results Compared with group B, liver injury and liver function of the patients in group A were obviously ameliorated, and the serum level of TNF-? and IL-6 significantly decreased (P
ABSTRACT
Objective To evaluate the effects of kurorinone combined with thymosin on the treatment of chronic hepatitis B. Methods 178 patients with chronic hepatitis B were randomly divided into group A, B and C. 64 patients in group A received kurorinone combined with thymosin for 3 months. 58 patients in group B received kurorinone only, and 56 patients in group C received thymosin only. Results At the end of treatment, HBeAg and HBV DNA negative-transformed rates were respectively 51.8% and 53.6% in group A, but 32.7% and 34.6% in group B, 21.6% and 21.6% in group C, the differences were statistically significant (P