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1.
Acta bioquím. clín. latinoam ; 57(3): 263-272, set. 2023. graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1533346

ABSTRACT

Resumen Las alergias alimentarias representan un problema de salud pública. La declaración de alérgenos en el rótulo implicó un avance fundamental para la gestión del riesgo, ya que evitar el alimento desencadenante mediante el rotulado adecuado constituye actualmente una medida insustituible de cuidado para la población susceptible. Se realizó una valoración del impacto de la legislación nacional en referencia a la declaración de alérgenos alimentarios entre 2017 y 2022. Se utilizaron los motores de búsqueda interna de la Administración Nacional de Medicamentos, Alimentos y Tecnología Médica (ANMAT) para los retiros de productos alimenticios del mercado y se contrastó como herramienta de medición indirecta para la valoración del impacto de la implementación del Artículo 235 séptimo del Código Alimentario Nacional (CAA). Se analizaron 43 productos (galletitas, fideos, chocolates, alimentos a base de vegetales). El 53,5% (23 sobre un total de 43) presentaba declaración de alérgenos. El 70% de los mismos (16 sobre un total de 23) fueron categorizados "con inconsistencias" y el 14% (6 productos de 43) utilizaba etiquetado precautorio. El paradigma reactivo del control de alimentos sobresalió por sobre el de las auditorías, los programas de monitoreo y, en suma, sobre los programas de prevención, ya que el sistema se activó fundamentalmente por la vía reactiva de las denuncias. Esto representó un 72% de los productos categorizados.


Abstract Food allergies represent a public health problem. The declaration of allergens on the label implied a fundamental advance for risk management, since avoiding the triggering food through proper labelling is currently an irreplaceable measure of care for the susceptible population. An assessment of the impact of the national legislation was carried out in reference to the declaration of food allergens between 2017 and 2022. The ANMAT internal search engines were used for the withdrawals of food products from the market and contrastlised as an indirect measurement tool for the impact assessment of the implementation of Section 235 seventh of the Argentine Food Code (CAA, for its acronym in Spanish). Forty-three products (biscuits, noodles, chocolates, vegetable-based foods) were analysed. The allergen declaration was present in 53.5% (23 out of a total of 43). Some inconsistencies were present in 70% of them (16 out of a total of 23) and 14% (6 products out of 43) used precautionary labelling. The reactive paradigm of food control stood out above that of audits, monitoring programmes and, in short, prevention programmes, since the system was activated fundamentally through the reactive route of complaints. This represented 72% of the categorised products.


Resumo As alergias alimentares representam um problema de saúde pública. A declaração de alérgenos no rótulo envolveu um avanço fundamental para a gestão do risco, visto que evitar os alimentos que desencadeiam as alergias, por meio de uma rotulagem adequada, é atualmente uma medida insubstituível de cuidado para a população suscetível. Foi realizada uma avaliação do impacto da legislação nacional referida à declaração de alérgenos alimentares entre 2017 e 2022. Os motores de busca interna da ANMAT (Administração Nacional de Medicamentos, Alimentos e Tecnologia Médica) foram utilizados para as retiradas de produtos alimentares do mercado e contrastados como uma ferramenta indireta de medição para a avaliação do impacto da aplicação do artigo 235 sétimo, do CAA (Código Alimentar Nacional). Foram analisados 43 produtos (biscoitos, macarrão, chocolates, alimentos à base de vegetais). 53,5% (23 de um total de 43) apresentavam declaração de alérgenos, 70% deles (16 de um total de 23) foram categorizados "com inconsistências" e 14% (6 produtos de 43) utilizavam rotulagem de precaução. Destacou-se o paradigma "reativo" do controle de alimentos por sobre o controle das auditorias, dos programas de monitoramento e, em resumo, dos programas de prevenção, visto que o sistema foi ativado fundamentalmente pela via reativa das reclamações. Isso representou 72% dos produtos categorizados.

2.
Indian Pediatr ; 2023 Jul; 60(7): 549-552
Article | IMSEAR | ID: sea-225439

ABSTRACT

Objective: We examined the ‘nutrients of concern’ in pre-packaged food products that are commonly advertised, as per WHO standards and Nova Classification. Methods: This was a qualitative study, using a convenience sampling method, to identify advertisements of prepackaged food products. We also analyzed their content from information on the packets, and their compliance with applicable Indian laws. Results: We found that all the advertisements of the food products in this study did not provide important information about the amount of nutrients of concern i.e., total fat, sodium, and total sugars. These advertisements mostly targeted children, made health claims, and used endorsements of celebrities. All the food products were also found to be ultra-processed in nature and high in one or more nutrients of concern. Conclusion: Most of the advertisements are misleading, needing effective monitoring. Health warnings on the front-of- pack label and restrictions on marketing of such food products may go a long way in reducing non-communicable diseases.

3.
Article | IMSEAR | ID: sea-221381

ABSTRACT

The groundwork for extracting a significant amount of biomedical information from unstructured texts into structured formats is the difficult research area of biological entity recognition from medical documents. The existing work implemented the named entity recognition for diseases using the sequence labelling framework. The performance of this strategy, however, is not always adequate, and it frequently cannot fully exploit the semantic information in the dataset. The Syndrome Diseases Named Entity problem is presented in this work as a sequence labelling with multi-context learning. By using well-designed text/queries, this formulation may incorporate more previous information and to decode it using decoding techniques such conditional random fields (CRF). We performed experiments on three biomedical datasets, and the outcomes show how effective our methodology is on the BC5CDR-Disease, JNLPBA and NCBI-Disease, compared with other techniques our methodology performs with accuracy levels of 96.70%,98.65 and 96.72% respectively.

4.
Japanese Journal of Drug Informatics ; : 76-82, 2023.
Article in Japanese | WPRIM | ID: wpr-1006931

ABSTRACT

Objective: Health information, including the labelling, must be presented in a manner that is easily understandable to consumers. In recent years, the European Union and the United States have introduced standards for providing health information in a way that is easy for consumers to understand. The Clear Communication Index (CCI) published by the Centers for Disease Control and Prevention (CDC) is a useful tool for this purpose. Unfortunately, there is no such tool in Japan. Therefore, focusing on the package labelling of foods with functional claims (FFCs) sold in Japan, we constructed a Functional Clear Communication Index (F-CCI) and evaluated the FFCs.Methods: The F-CCI was developed by six people, including university staff with pharmacist qualifications and public health experts, by referring to the CDC CCI. The evaluation of FFCs using the F-CCI was performed using the Delphi method, which is one of the formal consensus-building methods in the field of health and medical information. The evaluation was conducted by three qualified pharmacists on five FFC products, and the degree of internal agreement among the evaluators was calculated using Fleiss’ κ.Results: The F-CCI consisted of 18 items that assessed the FFC characteristics. After assessing the labelling of FFCs using the F-CCI, the scores of all the materials ranged between 70 and 80% on the F-CCI, and none achieved 90%, which was considered the acceptable standard (overall κ value_ 0.865). Moreover, it was clear that the ‘readability’ and ‘understandability’ of the labelling were inadequate.Conclusion: The F-CCI developed in this study for the objective evaluation of the labelling of FFC products will act as a tool that will subsequently lead to the proper understanding and use of FFCs by consumers. Further efforts are needed to build and disseminate such tools and user-friendly ways of providing relevant information.

5.
Rev. peru. med. exp. salud publica ; 39(4): [480-488], oct. 2022. tab
Article in Spanish | LILACS | ID: biblio-1424350

ABSTRACT

La venta de productos ultraprocesados y el sobrepeso y la obesidad han aumentado en América Latina en los últimos años. En el Perú, se aprobó la Ley N° 30021 en busca de reducir el sobrepeso y la obesidad en niños y adolescentes, sin embargo, el desarrollo de esta Ley se caracterizó por tener continuas modificaciones en los diversos documentos elaborados. El propósito de este artículo es identificar cambios esenciales en los documentos elaborados por el Gobierno y el Congreso en el marco de la Ley N° 30021, específicamente en los temas de regulación de la publicidad de alimentos y bebidas no alcohólicas, advertencias publicitarias y parámetros técnicos de nutrientes críticos. Los cambios identificados en los diferentes documentos muestran el dinamismo en el desarrollo de esta política donde la falta de evidencia científica oportuna, la oposición de la industria alimentaria y la falta de consenso político fueron los principales motivos.


The sale of ultra-processed products has increased in Latin America in recent years, as well as the prevalence of overweight and obesity. In Peru, Law No. 30021 passed in an attempt to reduce overweight and obesity in children and adolescents; however, the development of this law was characterized by constant modifications to the documents prepared in this regard. This article aims to identify essential modifications in the documents elaborated by the Government and the Congress within the timeframe of Law No. 30021, particularly those regarding the regulation of food and non-alcoholic beverage advertising, advertising warnings and technical parameters of critical nutrients. The lack of timely scientific evidence, the opposition by the food industry and the lack of political consensus were the main reasons for the detected modifications, which shows the dynamism during the development of this policy.


Subject(s)
Products Publicity Control , Food Publicity , Food Labeling , Legislation, Food , Peru , Politics , Food and Beverages , Products Commerce , Policy
6.
Article | IMSEAR | ID: sea-218694

ABSTRACT

Human health mostly depends on quality food habits. In the rural area of Bangladesh, the people are in ill health due to the consumption of impure food which affects normal daily life. The study investigates rural, educated people thinking about purchasing quality foods and package food labelling. A field study was conducted at Hatibandha and Kaliganj Upazila of the Lalmonirhat district of Bangladesh with a structured questionnaire. The study shows that the people of rural areas are highly aware of their attitudes about food quality. Those with a comparatively high educational background are more conscious of maintaining food quality.The Study results also find that the rural people have very little knowledge and understanding of government rules and regulations regarding food quality and labelling.

7.
Indian J Prev Soc Med ; 2022 Sept; 53(3): 193-198
Article | IMSEAR | ID: sea-224013

ABSTRACT

Background: Public health initiatives focused on improving food at the community level to reduce the risk of nutritionrelated disorders have gained pace in light of the enormous illness burden associated with chronic diseases connected to nutrition. Delivering straightforward, pertinent, and understandable information regarding the nutritional value of food is the goal of Front of Package Labelling (FoPLs), which are intended to assist consumers in choosing healthier foods at the point of purchase. Methodology: It was a cross-sectional study carried out online through a series of webinars using an online survey platform and a feedback-designed questionnaire to ascertain webinar participants' knowledge of front of package labeling. Results: Among the participants, only 75.4% correctly identified the characteristics of packaged foods that increase the risk of obesity. Also, it was found that 84.7% of the participants knew that food labels had to display complete nutritional information. About 93.6 percent of the individuals were aware of public health initiatives that raise awareness of FOPL. Only 38.9% of the individuals were aware that certain food products were free from labelling, in comparison. Conclusion: Front of package labelling (FOPL) regulation goals must be adopted in order to enable consumers to simply, quickly, and accurately identify items containing extra sugars, trans-fats, oils, and sodium. This will help the Government of India comply with WHO recommendations on unhealthy foods.

8.
Rev. chil. nutr ; 49(1)feb. 2022.
Article in English | LILACS-Express | LILACS | ID: biblio-1388584

ABSTRACT

ABSTRACT The present work aimed to assess Uruguayan consumers support of the inclusion of nutritional warnings on four types of retail food establishments and to obtain consumer insights on how the warnings could be implemented in such establishments. For this purpose, an online survey was conducted with a non-probabilistic sample of 547 participants recruited via an advertisement on social media. Participants were requested to indicate their degree of agreement with the implementation of nutritional warnings in bakeries, delicatessens, fast-food restaurants and while ordering food online, and to provide ideas on how to include this information for each establishment. Results suggested that the inclusion of nutritional warnings in retail food establishments was positively perceived by participants. Participants highlighted that warnings should be highly visible to customers while making purchase decisions, so they become a relevant cue for making food choices. In particular, the retail display case and menu boards were identified as key locations for warnings in bakeries, delicatessen, and fast food restaurants, respectively. These results contribute valuable insights on how to implement the extension of nutritional warnings to unpackaged foods or foods made and packaged at the point of purchase.


RESUMEN El presente trabajo tuvo como objetivo evaluar la percepción de los consumidores uruguayos en relación a la implementación de advertencias nutricionales en cuatro puntos de venta de comida y generar ideas sobre cómo podría implementarse esta medida. Se realizó un estudio online con una muestra no probabilística de 547 participantes, reclutados utilizando publicidad en redes sociales. Los participantes indicaron su grado de acuerdo con la implementación de advertencias nutricionales en panaderías, rotiserías, lugares de venta de comida rápida y sitios de pedidos online, y proporcionaron ideas sobre cómo incluir esta inforamción en cada punto de venta. Los resultados sugieren que la población tiene una perecpeción positiva sobre la inclusión de advertencias nutricionales en puntos de venta de comida. Los participantes destacaron la importancia de incluir esta información en un lugar visible al momento de elegir los productos, de forma que pueda ser tenida en cuenta al tomar las decisiones. En particular, las vitrinas y la cartelería/pizarras fueron identificados como lugares estatégicos para la inclusión de advertencias nutricionales en panaderías/rotiserías y puntos de venta de comida rápida, respectivamente. Los resultados proporcionan valiosa información para extender la inclusión de advertencias nutricionales a puntos de venta de comida.

9.
Rev. chil. nutr ; 48(4)ago. 2021.
Article in English | LILACS-Express | LILACS | ID: biblio-1388518

ABSTRACT

ABSTRACT The aim of the present work was to explore the influence of consumer characteristics on purchase decisions when facing products with nutritional warnings a few days after their implementation in Uruguay. A non-probabilistic sample of 917 participants was obtained using an advertisement on social media. Participants were asked if they had seen the warning signs when making their food purchases and if they had seen the warnings on any product they intended to buy. Participants who answered affirmately (n= 616) were asked about their purchase decision by answering the question "What have you done with the product?" using the following response options: 'I purchased it anyway', 'I purchased a similar product with fewer excess signs', 'I purchased a similar product without excess signs', 'I didn't purchase the product or any similar one'. Univariate and multivariate multinomial logistic regression models were used to explore the influence of individual variables on participants' likelihood of having taken different decisions when facing a product with warnings. Results showed that participants older than 55 years were more likely to react to the warnings by purchasing a similar product with fewer warnings or by not purchasing any product. Likelihood of modifying purchase decisions due to the inclusion of the warnings was associated with a frequent consumption of natural and minimally processed foods and a low consumption frequency of ultra-processed products. These results provide insights to target efforts to promote the use of nutritional warnings in decision making.


RESUMEN El objetivo del presente trabajo fue explorar la influencia de caraterísticas de los consumidores en sus decisiones de compra al enfrentar productos con advertencias nutricionales, unos días después de su implementación en Uruguay. Se obtuvo una muestra no probabilística de 917 participantes utilizando redes sociales. Se les preguntó a los participantes si habían visto las advertencias en un producto que tenían la intención de comprar. A los participantes que respondieron afirmativamente (n= 616) se les pidió qué indicarn qué habían hecho con el producto, utilizando las siguientes opciones de respuesta: 'Lo compré igual', 'Compré un producto similar con menos símbolos de exceso', 'Compré un producto similar sín símbolos de exceso' y 'No compré el producto ni tampoco otro similar. Los datos se analizaron utilizaron modelos de regresión multinomial univariados y multivariados. Los participantes mayores de 55 años presentaron una mayor probabilidad de reaccionar a las advertencias no comprando el producto. La probabilidad de modificar la decisión de compra debido a las advertencias estuvo asociada con una mayor frecuencia de consumo de alimentos naturales y mínimamente procesados y una menor frecuencia de consumo de productos ultra-procesados. Los resultados del presente trabajo sugieren que los esfuerzos para promover el uso de las advertencias en la toma de decisiones deben estar focalizados en los ciudadanos con el mayor consumo de productos ultra-procesados.

10.
Poblac. salud mesoam ; 18(2)jun. 2021.
Article in Spanish | LILACS, SaludCR | ID: biblio-1386911

ABSTRACT

Resumen Introducción: Conocer los aspectos sociodemográficos de la alfabetización en salud y las necesidades relacionadas con el etiquetado de medicamentos permite crear las bases para canalizar las acciones de los profesionales para la mejora de la atención sanitaria que se brinda a poblaciones vulnerables. Metodología: A partir de ello, se realizó una investigación de tipo cuantitativa, observacional, con un alcance exploratorio que abordó la población indígena residente en el sector de Alto Telire, localizado en la provincia de Limón, Costa Rica. Esta se caracteriza por su aislamiento y baja escolaridad. En este artículo se presenta la caracterización de aspectos sociodemográficos y de alfabetización en salud, así como la identificación de necesidades relacionadas con el etiquetado de medicamentos para un grupo de pacientes de la etnia cabécar, atendidos en el mes de mayo del 2018 por personeros de la Caja Costarricense del Seguro Social (CCSS). Los resultados se obtuvieron mediante la realización de entrevistas directas a pacientes. Resultados: Los resultados obtenidos del estudio destacan que el 57 % de la población participante es del sexo femenino, con edades entre los 18 y 45 años. Además, el nulo acceso a la educación que tuvo la población hasta el año 2009 explica por qué el 70,42 % de las personas participantes no cuentan con ningún tipo de escolaridad, lo cual está relacionado con que el 100 % presentaran un bajo nivel de alfabetización en salud. Por otro lado, las principales formas de las personas participantes de reconocer sus medicamentos es por el nombre, uso y características físicas, siendo el uso que se le da al medicamento la principal manera de reconocerle. Conclusiones: La población incluida en este estudio cuenta con baja escolaridad y un nivel inadecuado de alfabetización para la salud. Las necesidades con respecto al etiquetado de medicamentos están relacionadas principalmente con el motivo de uso y la persona que lo debe utilizar. Adicionalmente, el etiquetado de los medicamentos es la única fuente de información que tiene esta población al alcance para utilizar racionalmente los medicamentos.


Abstract Introduction: The understanding of sociodemographic characteristics, health literacy, and drug labeling needs allows to create the bases for professionals to target actions for the improvement of healthcare among vulnerable populations. Methodology: From this, a quantitative, observational research was carried out, with an exploratory scope; that addressed the indigenous population residing in the Alto Telire sector, located in the province of Limón, Costa Rica, which is characterized by its isolation and low schooling. This article presents the characterization of sociodemographic aspects, health literacy, as well as the identification of needs related to the labeling of medicines for a group of patients of the Cabécar ethnic group, attended in May 2018 by representatives of the Costa Rican Social Security Fund (CCSS). The results were obtained through direct interviews with patients. Results: The results obtained from the study highlight that 57% of the participating population is female, with ages between 18 and 45 years. Furthermore, the lack of access to education that the population had until 2009 explains why 70 42% of the participants do not have any type of education, which is related to the fact that a 100% have low health literacy level. On the other hand, participants recognize their medications principally by the name, use and physical characteristics, being the use given to the medication the main way to recognize it. Conclusions:The population included in this study has low education and an inadequate level of health literacy. Drug labeling needs are primarily related to indications and the person intended to use it. Furthermore, drug labels are the only source of information available to this population in order to rationally use their treatments.


Subject(s)
Humans , Pharmaceutical Preparations , Health Literacy , Indigenous Peoples , Pharmacy , Costa Rica
11.
China Journal of Chinese Materia Medica ; (24): 1574-1579, 2021.
Article in Chinese | WPRIM | ID: wpr-879063

ABSTRACT

The research on the historical production areas of Dao-di herbs is of great value to the quality evaluation, production base and protection for geographic indications of Dao-di herbs. Current studies mostly focused on the sorting of written sources, but neglected the excavation of image records such as historical maps and topographic maps. This paper aims at exploreing the geographical scope and evolution mode of historical production area of the Dao-di herbs by combining the method of historical map labelling with the traditional literature and historical research methods. It can be divided into three steps: production area name extraction, historical map labelling and textual research on the historical production area of Dao-di herbs. This method may provide a better way to show the geographical scope and topographic features of the historical production areas of Dao-di herbs through historical maps labelling, which is essential to further explore the evolution of production areas of Dao-di herbs from ancient times to the present by comparing historical maps of different periods, and may be helpful to discover the reasons for the formation and evolution of historical producing areas of Dao-di herbs from different perspectives such as environment, climate, humanities, economy, policy, etc. In addition, the historical map database can be used for map labelling to help establish the relationship between the dynasties, historical names, and change cha-racteristics of the scope of the historical production areas of Dao-di herbs in the following research.


Subject(s)
Drugs, Chinese Herbal , Geography , Medicine, Chinese Traditional , Plants, Medicinal , Research Design
12.
J. appl. oral sci ; 29: e20200751, 2021. tab, graf
Article in English | LILACS | ID: biblio-1154613

ABSTRACT

Abstract Objective To investigate the Ki 67 expression and its correlation with clinicopathological features and 3 years as well as 5 years survival rate in oral squamous cell carcinoma (OSCC). Methodology Total 217cases of OSCC primarily treated with surgery with or without radiation were included. All patients were followed up for 3 years and 150 were followed up of 5 years for disease free survival. The immunohistochemistry was carried out on neutral buffered formalin fixed paraffin embedded tissue to evaluate the expression of Ki67. Results The Ki67 labeling index (LI) was significantly higher with respect to adverse clinicopathological parameters such as histopathological grading (p<0.001), clinical TNM staging (p<0.001) and nodal metastasis (p<0.001). The OSCC patients survived for less than 3 and 5 years were showed significantly higher Ki67 LI as compared to diseases free survived more than 3 and 5 years(p<0.001). The three years survival rate of OSCC patient significantly higher with low Ki67 LI (≤45) 96.2%, followed by moderate Ki67 LI (46 to 60) 60.7% and high Ki67 LI (≥61) 37.7% (p<0.001). The five years survival rate of OSCC patient statistically significantly higher with low Ki67 LI (≤45)93.3%, followed by moderate Ki67 LI (46 to 60) 46.8% and Ki67 LI (≥61) 23.3% (p<0.001). Conclusion The measurement of cell proliferative activity by using Ki67 antigen expression in individual OSCC might provide unique, predictive information on clinical outcome, prognosis and deciding treatment modalities in OSCC.


Subject(s)
Humans , Mouth Neoplasms , Carcinoma, Squamous Cell , Head and Neck Neoplasms , Prognosis , Biomarkers, Tumor , Ki-67 Antigen , Squamous Cell Carcinoma of Head and Neck
13.
Rev. peru. med. exp. salud publica ; 37(4): 726-732, oct.-dic. 2020. tab
Article in Spanish | LILACS | ID: biblio-1156826

ABSTRACT

Resumen El objetivo del estudio fue describir la oferta y la publicidad de alimentos y bebidas en instituciones educativas y entornos escolares de 15 colegios públicos y privados de Lima en 2019. Se realizaron observaciones inopinadas y se registraron los alimentos ofrecidos, la presencia de advertencias publicitarias, octógonos y la publicidad en quioscos y cafeterías. A la hora de salida se observó la venta ambulatoria de alimentos. Todas las escuelas ofrecían productos ultraprocesados, el 73,3% vendía alimentos con octógonos y el 60% tenía publicidad de alimentos procesados y ultraprocesados. En el 86,7% de los colegios había vendedores ambulantes de alimentos, varios de los alimentos eran productos ultraprocesados. Los resultados sugieren un ambiente alimentario no saludable dentro y alrededor de las escuelas, y el incumplimiento de la regulación actual. Resulta necesario mejorar la difusión y supervisión de la política alimentaria, y construir con las escuelas estrategias para promover una alimentación saludable.


Abstract This study aimed to describe the supply and advertising of foods and beverages both inside educational institutions and in their respective local areas in 15 public and private schools in Lima during 2019. Unbiased observations were recorded regarding the types of food available, the presence of octagons, and advertisements used in kiosks and cafeterias. Mobile food vendors were observed at the end of the school day. All schools offered processed products, 73.3% sold food with octagons, and 60% displayed advertising for processed and ultraprocessed foods. Mobile food vendors were observed in 86.7% of schools, several of which were found to sell ultraprocessed products. The results suggest an unhealthy food environment both inside and outside schools, and a noncompliance with current regulations. It is therefore necessary to improve the dissemination and supervision of the food policy, and develop strategies with schools to promote healthy eating.


Subject(s)
Schools , Food and Beverages , Food Publicity , Commerce , Street Food , Food Publicity , Food , Legislation, Food
14.
Article | IMSEAR | ID: sea-212639

ABSTRACT

Background: Cervical cancer is known to have a good response to radiotherapy. The response and prognosis are dependent on the level of apoptosis. Pap smear and histopathology are cost-effective methods in diagnosing premalignant and malignant lesions of cervix but not accurate in classifying and estimating the progression of the disease, especially in premalignant lesions. Therefore this study was undertaken to know the role of Ki-67 expression and apoptotic index in classifying accurately the premalignant lesions for better management.Methods: The study included 540 cases diagnosed histologically as cervical intraepithelial neoplasia or carcinoma. The apoptotic index is calculated for all the 540 cases using light microscopy on Haematoxylin and Eosin stained sections. Ki-67 immunohistochemical staining was done for 100 cervical biopsies. Ki-67 expression was graded and the Ki-67 labelling index was calculated. Statistical evaluation was done using the unpaired t-test.Results: The Apoptotic index increased with increasing grade of dysplasia. There is a significant difference in the mean apoptotic index between premalignant and malignant lesions of the cervix. The ki-67 index increased with increasing grade of dysplasia. There is a significant difference in the mean Ki-67 index between premalignant and malignant lesions of the cervix.Conclusions: Apoptotic index and proliferative indices have been found useful in distinguishing between premalignant and malignant lesions of the cervix and gives an idea about the proliferative activity of the tumour for better management of the patient and to determine prognosis.

15.
Perspect. nutr. hum ; 22(1): 35-45, ene.-jun. 2020. tab, graf
Article in Spanish | LILACS | ID: biblio-1346663

ABSTRACT

Resumen Antecedentes: el etiquetado nutricional frontal es una herramienta para orientar la elección del con sumidor hacia una dieta equilibrada y sana. Objetivo: conocer el modelo de etiquetado nutricional frontal que más influye en la identificación de calorías y nutrientes críticos de productos industria lizados en adultos de Lima, Perú. Materiales y métodos: estudio cuasiexperimental-transversal en el que participaron 384 adultos de ambos sexos distribuidos en cuatro grupos equitativos: sin modelo de etiquetado nutricional, Guía Diaria de Alimentación, etiquetado de advertencia octogonal y Guía Diaria de Alimentación-semáforo. A cada participante se le aplicó un cuestionario con 10 figuras de empaques con el modelo de etiquetado, según el grupo al que correspondían, y 10 preguntas, con un puntaje total de 0 al 20, según el número de respuestas positivas en la identificación de calorías y nutrientes críticos. Resultados: los mayores puntajes totales fueron para los grupos Guía Diaria de Alimentación-semáforo (12,1±3,9) y Guía Diaria de Alimentación (12,1±3,7), con diferencias significativas respecto a los otros dos grupos. También se presentaron diferencias en los puntajes de la identificación de calorías, grasas saturadas y grasa total; los valores más altos fueron para los dos grupos señalados (p<0,05). No se observaron diferencias en la identificación de azúcar y sodio. Conclusiones: los modelos Guía Diaria de Alimentación y Guía Diaria de Alimentación-semáforo son los que más influyen en la identificación de calorías y nutrientes críticos.


Abstract Background: A front-of-package nutrition label is a tool to help guide food selection towards a balanced and healthy diet. Objective: To understand the model of front-of-package nutrition label that most influences the understanding of calories and important nutrients in processed food products in adult participants in Lima, Peru. Materials and Methods: A quasi-experimental cross-sectional study with 384 participant adults of both sexes. Participants were distributed into four equal groups: no nutritional labeling; daily food guide; stop sign warning labeling; and daily food guide with a traffic light symbol. Each participant was given a questionnaire with 10 pictures of food packaging with the labeling model that corresponded to their randomized group, along with 10 additional questions, for a total of 20 possible questionnaire points. Points were given for correct answers to the 20 questions on the questionnaire, such as identifying correctly the number of calories and/or critical nutrients. Results: The highest total scores were for the daily food guide-traffic light group (12.1 ± 3.9) and daily food guide group (12.1 ± 3.7), with significant differences with respect to the other two groups. There were also differences in the scores of the identification of calories, saturated fat, and total fat; the highest values were for the same two groups indicated above (p <0.05). No differences in food labels were found for the identification of sugars or sodium. Conclusions: The daily food guide and daily food guide-traffic light models most influence the identification of calories and critical nutrients.


Subject(s)
Food Labeling
16.
Nucleus (La Habana) ; (67): 39-43, ene.-jun. 2020. tab, graf
Article in Spanish | LILACS-Express | LILACS | ID: biblio-1143358

ABSTRACT

Resumen Para la obtención de radiotrazadores sólidos de 99mTc actualmente se necesitan nuevos soportes porosos. Estudios anteriores realizados por otros autores mostraron la posibilidad del marcaje con 99mTc de sedimentos de ríos con alto contenido de aluminosilicatos. En el presente trabajo se desarrolló una metodología para el marcaje de arena sílice con el 99mTcO4- para su uso como radiotrazador sólido. Se realizó el marcaje de la arena sílice previamente tratada y sin tratar empleando concentraciones variables de cloruro y fluoruro estañoso como agentes reductores y diferentes tiempos de marcaje. Se evaluó la influencia de la etapa de tratamiento previo de la arena en los rendimientos de retención del Tc obtenidos. Los cambios en la composición de la arena sílice luego de su tratamiento previo se pudieron constatar a partir de la Microscopía Electrónica de Barrido (SEM-EDS). Los resultados sugirieren el empleo de la arena sílice previamente tratada y de fluoruro estañoso como agente reductor, adicionalmente se propusieron modificaciones a la metodología inicial de tratamiento previo de la arena. Se pudo constatar a partir de la técnica SEM-EDS que el aumento del porciento de retención del Tc en la arena luego de su tratamiento, se debe fundamentalmente a los cambios observados en su composición química y en su estructura. Se logró la obtención de un radiotrazador sólido marcado con 99mTc en soporte de arena sílice con un tiempo de preparación estimado de 4 horas y un rendimiento de retención de 74%.


Abstract To obtain 99mTc solid radiotracers, new porous supports are currently needed. Previous studies carried out by other authors showed the possibility of 99mTc labeling of sediments from rivers with a high content of aluminosilicates. In the present work a methodology for labeling of silica sand with 99mTcO4- as a prospective solid radiotracer was developed. Labeling of the previously treated and untreated silica sand was carried out using variable concentrations of chloride and stannous fluoride as reducing agents and different labeling times. The influence of the pre-treatment stage of the sand on the obtained Tc retention yields was evaluated. The changes in the composition of the silica sand after its previous treatment could be verified from the Scanning Electron Microscopy (SEM-EDS). The results suggested the use of previously treated silica sand and stannous fluoride as a reducing agent, modifications were proposed to the initial methodology of previous treatment of the sand. It was possible to confirm from the SEM-EDS technique that the increase in the percentage of retention of Tc in the sand after its treatment is mainly due to the observed changes in its chemical composition and structure. It was possible to obtain a 99mTc solid radiotracer on support of silica sand with an estimated preparation time of 4 hours and a retention yield of 74%.

17.
Demetra (Rio J.) ; 15(1): 45847, jan.- mar.2020. tab, ilus
Article in English, Portuguese | LILACS | ID: biblio-1096028

ABSTRACT

A rotulagem de alimentos é importante para a comunicação entre produtores e consumidores. No entanto, para ajudar os consumidores a ter maior autonomia em suas escolhas alimentares, é importante interpretar corretamente a rotulagem dos alimentos. Assim, esta pesquisa avaliou o conhecimento e o uso das informações nutricionais apresentadas nos rótulos dos alimentos. Pesquisa quantitativa, exploratória e transversal, realizada em 2018 em uma universidade pública no Brasil, com 415 consumidores com 18 anos ou mais. Para avaliar o conhecimento, aplicouse questionário estruturado com pontuação de 0 a 24. Os dados foram analisados por meio de análise descritiva, correlação de Spearman e teste de Kruskal-Wallis e Mann Whitney. Participaram indivíduos com idade de 21,02 ± 2,89 anos, dos quais 58,31% eram do sexo feminino. Muitos consumidores liam frequentemente os rótulos dos alimentos (56,39%). A pontuação média de conhecimento foi de 14,99 ± 4,12. A média do escore de conhecimento foi afetada pela idade (p = 0,039) e renda (p = 0,020). Os participantes que utilizaram alegações nutricionais como critério de compra (p = 0,004) obtiveram maiores pontuações. Os maiores problemas na interpretação dos rótulos nutricionais estavam relacionados às reivindicações obrigatórias de nutrientes e aos termos "zero gordura trans (0%)", "alimento funcional", "diet" e "light". Considerando que a regulamentação dos rótulos de alimentos está em processo de revisão no Brasil, torna-se importante pesquisar seu uso e conhecimento por consumidores adultos jovens. Isso contribuirá para a discussão da revisão da legislação, além de ajudar os profissionais a orientarem os consumidores na interpretação dos rótulos. (AU)


Food labelling is important to communication between food producers and consumers. For consumers to have greater autonomy in terms of their food choices, it is important to facilitate a correct interpretation about what is on a food label. This paper assessed consumers' knowledge and use of nutritional information on food labels. Cross-sectional exploratory quantitative, "blind" research carried out in 2018 in a public university in Brazil, with 415 consumers aged 18 years or older. A structured questionnaire with a score ranging from 0 to 24 was applied. Descriptive analysis, Spearman correlation coefficient, the Kruskal-Wallis test and the Mann Whitney test were employed. Participants were individuals aged 21.02 ± 2.89 years, of which 58.31% were female. Many consumers reported they read food labels frequently (56.39%). The mean score was 14.99 ± 4.12. The knowledge score mean was affected by age (p =0.039) and income (p = 0.020). Participants who used nutritional claims as a criterion for purchase (p = 0.004) had higher scores. The biggest issues in interpreting nutritional labels were related to mandatory nutrient claims and the terms "trans-fat free (0%)", "functional food", "diet" and "light". Food label regulation is a process currently under review in Brazil, so research on the use and knowledge of nutritional information on food labels by young adult consumers becomes important. It will contribute to the discussion of the revision of legislation, as well as helping professionals guide consumers in the interpretation of labels. (AU)


Subject(s)
Humans , Male , Female , Adolescent , Adult , Middle Aged , Aged , Food Labeling , Knowledge , Nutritional Facts
18.
São Paulo med. j ; 137(5): 454-462, Sept.-Oct. 2019. tab
Article in English | LILACS | ID: biblio-1059099

ABSTRACT

ABSTRACT BACKGROUND: Package leaflets of medicines need to be intelligible, but tools for their evaluation are scarce. OBJECTIVE: To validate a new tool for assessing subjects' satisfaction with medicine package leaflets (LiS-RPL). DESIGN AND SETTING: Cross-sectional descriptive study conducted in two regions of Portugal (Lisbon and Centre). METHODS: 503 participants (53.1% male) were selected according to convenience and homogenously distributed into three groups: 1 to 6; 7 to 12; and > 12 years of schooling. LiS-RPL was developed based on international regulation guidelines and was initially composed of 14 items. Twelve package leaflets were tested. Dimensionality calculations included: exploratory factor analysis and minimum rank factor analysis; Kaiser-Meyer-Olkin index and Bartlett's sphericity test to assess matrix adequacy for exploratory factor analysis; exploratory bifactor analysis with Schmid-Leiman solution to detect possible existence of a broad second-order factor; and Bentler's Simplicity Index and Loading Simplicity Index to assess factor simplicity. Diverse coefficients were calculated to assess reliability. RESULTS: Minimum rank factor analysis detected a two-factor or single-factor structure. Exploratory factor analysis with 12 items showed a two-factor structure, explaining 69.11% of the variance. These items were strongly correlated with each other (r = 0.80). Schmid-Leiman: all items seemed to represent the general factor (loadings above 0.50), which was 76.4% of the extracted variance. Simplicity indices were good (percentile 99): Bentler's Simplicity Index of 0.99 and Loading Simplicity Index of 0.48. Internal consistency indexes indicated good reliability. LiS-RPL was shown to be homogenous. CONCLUSION: LiS-RPL is a validated tool for evaluating subjects' satisfaction with medicine package leaflets.


Subject(s)
Humans , Male , Female , Personal Satisfaction , Surveys and Questionnaires/standards , Comprehension , Drug Labeling/standards , Consumer Health Information/methods , Portugal , Publications/standards , Reading , Cross-Sectional Studies , Drug-Related Side Effects and Adverse Reactions , Educational Status , Consumer Health Information/standards , Government Agencies
19.
Salud pública Méx ; 61(5): 609-618, sep.-oct. 2019. tab, graf
Article in Spanish | LILACS | ID: biblio-1127324

ABSTRACT

Resumen: Objetivo: Evaluar la comprensión objetiva de cinco tipos de etiquetados frontales de paquetes (EFP) (Sistema de Clasificación de Estrellas de Salud, Semáforo Múltiple, Nutri-Score, Ingestas de Referencia y Símbolo de Advertencia) en México. Material y métodos: Se reclutaron 1 001 consumidores mexicanos para clasificar tres productos de tres categorías de alimentos sin EFP, según su calidad nutricional. Se les asignó al azar uno de los cinco EFP para clasificar los mismos productos, esta vez con un EFP en el empaque. El cambio en la capacidad para clasificar correctamente los productos en las dos tareas fue evaluado por EFP, utilizando un modelo de regresión logística ordinal. Resultados: Nutri-Score y Semáforo Múltiple obtuvieron un mejor desempeño, seguidos del Símbolo de Advertencia, Sistema de Clasificación de Estrellas de Salud e Ingestas de Referencia. Conclusión: Nutri-Score y el Semáforo Múltiple surgen como esquemas eficientes para informar a los consumidores sobre la calidad nutricional de los alimentos en México, donde podrían ser una herramienta útil para los consumidores en situación de compra.


Abstract: Objective: This study aimed to compare consumers' objective understanding of five FoPLs [Health Star Rating system (HSR), Multiple Traffic Lights (MTL), Nutri-Score, Reference Intakes (RIs), Warning Symbol] in Mexico. Materials and methods: 1 001 Mexican consumers were recruited and asked to rank three sets of label-free products according to their nutritional quality, via a survey. Upon completion of this task, participants were randomized to one of five FoPL conditions and were again asked to rank the same sets of products, this time with a FoPL displayed on pack. Change in ability to correctly rank products across the two tasks was assessed by FoPL using ordinal logistic regression. Results: Nutri-Score and MTL performed best, followed Warning Symbol, HSR and RIs. Conclusion: Nutri-Score and MTL appear as efficient schemes to inform consumers on the nutritional quality of foods, in particular in Mexico, where it would be a helpful tool for consumers in purchasing situations.


Subject(s)
Humans , Male , Female , Adult , Middle Aged , Young Adult , Consumer Behavior , Food Labeling/methods , Nutritive Value , Socioeconomic Factors , Random Allocation , Logistic Models , Food/classification , Food Labeling/classification , Mexico , Nutritional Requirements
20.
Clinical Nutrition Research ; : 79-90, 2019.
Article in English | WPRIM | ID: wpr-739632

ABSTRACT

Since chronic diseases have emerged as a major cause of death worldwide, people has been exposed to large amounts of information on healthy eating practices that are important aspects of its prevention and management. Food literacy, the functional, interactive, and critical ability to manage dietary information with the aim of improving health, is of global interest. In South Korea (hereafter Korea), there is currently a lack of food literacy research, despite its pertinence for the development of public health policies that are tailored to recipients' ability to understand and address health and nutrition issues. In this study, the research trend and policy implications of food literacy are derived through reviewing preceding studies related to food literacy in Korea and elsewhere. Existing literature on food literacy in Korea placed much emphasis on the functional ability of food literacy. Future research on the operational definitions of interactive and critical food literacy and their health effects in Korea is necessary. In addition, there is a lack of research on the development and validation of measurement tools that evaluate integrative concepts of food literacy. To accurately examine the relationships among food literacy, diet, and health, standardized measurement tools that can comprehensively evaluate food literacy frameworks for various Korean sub-population groups should be developed. Based on such future studies, an investigation of health promotion programs or policies on reducing the cognitive burden of food literacy would contribute to improving heathy eating practices in Korea.


Subject(s)
Cause of Death , Chronic Disease , Consumer Health Information , Diet , Eating , Food Labeling , Health Education , Health Literacy , Health Promotion , Korea , Literacy , Public Health
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