Adult Onset Leuko-encephalopathy, Cerebral Calcifications and Cysts.

Leuko-encephalopathy, brain calcifications and cysts (LCC) known as Labrune syndrome, is a rare syndrome. It is primarily described in childhood and adolescence as presenting with neurological impairment of relatively rapid progression and intra-cerebral hemorrhage that frequently leads to death. The etiology is unknown & there is no specific clinical feature suggestive of this disorder. Here in, we report a 34-year old man with LCC who had chronic Headache & neurological symptoms beginning in adulthood and discuss recently described entities in view of the relevant literature.