1.
Journal of Pharmaceutical Practice
;
(6): 114-115,134, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-790571
ABSTRACT
Oridonin is an en-kaurene diterpenoids compound which was found to have effect on tumor in vitro.But the clinical application has been limited because of poor water solubility,low bioavailability and oral absorption.Many scholars conducted a large number of structure modification researches of oridonin to search for new diterpenes with higher bio-activities and better bio-availabilities,and to develop new antitumor drugs.In this paper,studies on this aspect of oridonin were re-viewed.