ABSTRACT
The aerial part of Laggera pterodonta plant found in North-Central part of Nigeria was hydrodistilled and the volatile oil subjected to GCMS analysis. 23 components were identified in the essential oil of which n-Triacontane was the major constituent (~43%). Other major volatile constituents include, Dimethoxydurene (~9%), Caryophyllene oxide (~7%), Linoleoyl chloride (~7%), oleic acid (~4%), gamma-Eudesmol (~4%), 2,6,10-trimethylundeca-1,3,diene (~3%) and n-Dotriacontane (~3%). This is the first time that n-triacontane is being found as the major constituent of an essential oil, and also the first time the composition of the essential oil of Laggera pterodonta from North-central Nigeria is being reported.
ABSTRACT
To study the chemical constituents of aerial parts of Laggera pterodonta (DC.) Benth., the air-dried aerial parts of this plant were powered and extracted with boiling water and purified by silica gel column chromatography and recrystallized. Eleven compounds were obtained from L.pterodonta. They were identified as to be 6-O-β-D-glucopyranosyl-carvotanacetone (1), pterodontic acid (2), 1β-hydroxy pterondontic acid (3), pterodontoside A (4), pterodondiol (5), pterodontriol B (6), 5-hydroxy-3,4′,6,7-tetramethoxyflavone (7), artemitin (8), chrysosplenetin B (9), quercetin (10) and β-sitosterol (11). Compound 1 is a new monoterpene glucoside. Compounds 10 and 11 were isolated from this plant for the first time. Compounds 2 and 5 showed moderate activity against bacteria including Staphylococcus aureus, Pseudomonas aeruginosa, Bacillus subtilis, Mycobacteium phlei and Bacillus circulans by paper disc diffusion method, while they both displayed no activity against Escherichia coli.
ABSTRACT
The constituent of the volatile oils from Laggera pterodonta (DC) Benth was analyzed by GC/MS/DS and standard mass-spectrogram atlas. From which forty-eight compounds were identified and their relative contents were determined. Monoterpenoids, sesquiterpenoids and phenolic compounds, such as 2,6 bis (1,1-dimethyl ethyl)-4 ethyl phenol (28.27％) are the principal constituents.