Larynx-Preserving Partial Pharyngectomy via Lateral Pharyngotomy for the Treatment of Small (T1~2) Hypopharyngeal Squamous Cell Carcinoma

OBJECTIVES: To evaluate the oncologic and functional results of larynx-preserving partial pharyngectomy (LPP) via lateral pharyngotomy approach as a primary treatment for small (T1 or T2) hypopharyngeal squamous cell carcinoma (HPSCC). METHODS: We performed a retrospective review of 23 patients who underwent LPP through lateral pharyngotomy approach for small HPSCC at the our department between January 1991 and June 2007. Fourteen (61%) patients had adjuvant postoperative radiotherapy. RESULTS: The 2-years and 5-years disease specific survival rate was 77% and 61%, respectively. Nine patients (39%) had tumor recurrence. The most common pattern of recurrence was isolated distant failure (n=4, 44%) followed by local (n=2, 22%) and loco-regional (n=3, 34%) recurrence. The ultimate cure rate of the primary tumor was 87% (20 of 23). Twenty-two of the 23 patients (95%) could be decannulated, tolerate an oral diet, and had acceptable postoperative phonatory function. CONCLUSION: LPP via lateral pharyngotomy approach appears to be a feasible procedure for selected small HPSCC patients in terms of both oncologic and functional outcomes.

Larynx-Preserving Partial Pharyngectomy via Lateral Pharyngotomy for the Treatment of Small (T1~2) Hypopharyngeal Squamous Cell Carcinoma

OBJECTIVES: To evaluate the oncologic and functional results of larynx-preserving partial pharyngectomy (LPP) via lateral pharyngotomy approach as a primary treatment for small (T1 or T2) hypopharyngeal squamous cell carcinoma (HPSCC). METHODS: We performed a retrospective review of 23 patients who underwent LPP through lateral pharyngotomy approach for small HPSCC at the our department between January 1991 and June 2007. Fourteen (61%) patients had adjuvant postoperative radiotherapy. RESULTS: The 2-years and 5-years disease specific survival rate was 77% and 61%, respectively. Nine patients (39%) had tumor recurrence. The most common pattern of recurrence was isolated distant failure (n=4, 44%) followed by local (n=2, 22%) and loco-regional (n=3, 34%) recurrence. The ultimate cure rate of the primary tumor was 87% (20 of 23). Twenty-two of the 23 patients (95%) could be decannulated, tolerate an oral diet, and had acceptable postoperative phonatory function. CONCLUSION: LPP via lateral pharyngotomy approach appears to be a feasible procedure for selected small HPSCC patients in terms of both oncologic and functional outcomes.

Lateral Pharyngotomy as an Approach to the Oropharyngeal Cancer / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: The wide surgical resection combined with postoperative radiotherapy is commonly accepted as the most effective approach to the advanced stage of oropharyngeal cancers. As the lateral pharyngotomy provides a sufficient space to obtain enough surgical margin for surgical treatment of oropharyngeal cancers without disturbing the mandible, it can not only reduce the post-operative morbidity, but also obtain good functional results. To evaluate the efficiency and indication of lateral pharyngotomy as an approach to oropharyngeal cancers. MATERIALS AND METHODS: The medical records of 10 patients who had been treated by lateral pharyngotomy approach between 1994 and 1998 were reviewed retrospectively. RESULTS: The sites of primary tumor were the tonsil in 6 patients, the tongue involving the base and the tonsil fossa in 2 patients and the base of the tongue in 2 patients. Seven cases were T2 stage cancers and 3 cases were T3. No recurrences have risen on primary sites to date. Postoperative radiotherapy was performed within 29 to 43 days. Oral diet was possible within 16 to 29 days. Conclusions: As lateral pharyngotomy can avoid disturbing the mandible, thereby facilitating early postoperative radiotherapy, it is an excellent approach to the T2 or T3 oropharyngeal cancers with low postoperative morbidity and good functional results, especially when the open size of the mouth is proper.