ABSTRACT
El liquen plano pigmentoso invertido es una variante rara de liquen plano caracterizada por lesiones marrones o violáceas,de borde sobreelevado y centro atrófico, que afecta casi exclusivamente grandes pliegues. Es más frecuente en individuos caucásicos. Presentamos el caso de un paciente masculino de 57 años, con antecedente de politraumatismo y hemotransfusión en el año 1983, que consultó a nuestro servicio por presentar lesiones ligeramente pruriginosas en pliegues de tres años de evolución. La biopsia cutánea confirmó el diagnóstico de liquen plano y entre los estudios de laboratorio se detectó serología positiva para el virus de la hepatitis C (VHC). Con la clínica, el estudio histopatológico y los métodos complementarios arribamos al diagnóstico de liquen plano pigmentoso invertido asociado a VHC.
Lichen planus pigmentosus-inversus is a rare variant of lichen planus characterized by brown or violet lesions, raised edge andatrophic centre, which affects almost exclusively large folds. It is more common in Caucasians. A 57-year-old male with a historyof multiple trauma and blood transfusion in 1983 is presented. He consulted our service for slightly pruritic lesions in folds ofthree years of evolution. Skin biopsy confirmed the diagnosis of lichen planus and positive serology for hepatitis C virus (HCV)was detected on laboratory studies. With the clinical, histopathological and complementary methods we arrive to the diagnosisof lichen planus pigmentosus-inversus associated with HCV.
Subject(s)
Humans , Hepatitis , Hepatitis C , Lichen Planus , Autoimmunity , HIV Infections , Skin DiseasesABSTRACT
Lichen planus pigmentosus (LPP) is an uncommon variant of lichen planus, which manifests as hyperpigmented dark brown macular hyperpigmentations chiefly involving the face and upper extremities. The histopathologic changes consist of vacuolar degeneration of the basal layer, presence of dermal melanophages, and lichenoid lymphocytic infiltrations. LPP with exclusive localization in intertriginous areas is named as LPP-inversus, and is infrequently reported in previous dermatologic literature. A 16-year-old girl presented with several brownish to dark grayish patches on both axilla for 7 months. The lesions were asymptomatic and did not have preceding erythema. The patient had not come into contact with any chemicals and denied existence of previous allergy episodes, and her medical history was non-contributory. A skin biopsy from a brownish patch revealed vacuolar alteration of the basal layer, and band-like lymphocytic infiltration with pigment incontinence. We report a typical case of LPP-inversus with relevant literature.
Subject(s)
Adolescent , Humans , Axilla , Biopsy , Erythema , Hypersensitivity , Lichen Planus , Lichens , Skin , Upper ExtremityABSTRACT
Lichen planus pigmentosus-inversus is a rare variant of lichen planus pigmentosus. The eruption of lichen planus pigmentosus-inversus occurs mainly in the flexural regions and presents with brownish macules and patches. Here we describe the case of a 31-year-old Korean woman who presented with hyperpigmented lesions over her antecubital and popliteal area and groin. Physical examination revealed multiple brownish macules and patches on the intertriginous area without pruritis, and histologic findings showed a regressive pattern of lichen planus. These clinical and histological findings were consistent with a diagnosis of lichen planus pigmentosus-inversus.
Subject(s)
Adult , Female , Humans , Groin , Lichen Planus , Lichens , Physical Examination , PruritusABSTRACT
Lichen planus pigmentosus (LPP) is a rare variant of lichen planus, and it is characterized by hyperpigmented, dark brown to violaceous colored macules or patches on the sun exposed areas of the skin. The term of LPP-inversus was proposed to describe some cases with LPP arising on the intertriginous areas. Clinically, LPP-inversus is characterized by well defined dark brown to violaceous macules or patches with minimal symptoms and it is predominantly confined on the flexural areas. The histological characteristics are a lichenoid inflammatory infiltrate on the upper dermis, melanophages and pigmentary incontinence. The clinical course can vary. We present here an additional case of LPP-inversus that developed on the both inguinal folds and we review the relevant literature.
Subject(s)
Dermis , Lichen Planus , Lichens , Skin , Solar SystemABSTRACT
Lichen planus pigmentosus-inversus (LPP-inversus) is an extremely rare variant of lichen planus (LP), and only a few cases have been reported. Its course is characterized by exacerbations and remissions, and it is known to be more chronic than classical LP is. We report two cases of LPP-inversus and offer the suggestion that LPP-inversus may originate from LP of flexural areas.