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Objective To evaluate the reversibility of obesity-related arterial dysfunction and thickening carotid intima-media through dietary and/or exercise intervention programs.Methods Seventyeight 9 to 12 year-old overweight children,were randomly assigned to group A:only dietary modification,group B:diet plus a supervised structured exercise program for 6 weeks(SE)and subsequently for 1 year (CE).The prospectively defined primary end points were assessed through ultrasound-derived arterial endothelial function(endothelium-dependent dilation)of the brachial artery and intima-media thickness of common carotid artery.Results At 6 weeks,both interventions were associated with improved arterial endothelial function[group A:(6.36±0.81)% vs.(5.32±0.84)%,P＜0.01;group B:(7.46±0.91)% vs.(5.20±0.87)%,P＜0.01 ].A conbination of diet and exercise were associated with a significantly greater improvement in endothelial function than on diet alone(P＜0.01).At 1 year,there appeared significantly Less thickening of the carotid wall in group CE[(0.57±0.05)mm vs.(0.59±0.07)mm,P＜0.001].Compared with children in group SE[(6.38±1.04)% vs.(5.22±0.96)%,P＜0.05],vascular function appeared significantly better in group CE[(8.29±0.78)% vs.(5.38±0.65)%,P＜0.001].Conclusion Obesity-related vascular dysfunction in young children was partially reversible with diet alone but more obvious when combined with exercise training for 6 weeks.Sustained improvements at 1 year was seen in those who persisted in diet program plus regular exercise.
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@#ObjectiveTo observe the effect of square physical fitness exercise on the indexes of disease conditions, biology and blood lipids in patients with coronary heart disease (CHD).Methods125 CHD patients were divided into the exercise group (77 cases, taking part in the square physical fitness exercise) and control group (48 cases, not taking part in the square physical fitness exercise). The indexes of biology, disease conditions and blood lipids of all patients in two groups were tested.ResultsAfter exercise, the body mass, body mass index, waist circumference, numbers of ischemia attacks and duration of ischemia attack in patients of the exercise group were obviously lower than those before exercise ( P<0.05～0.01) and also lower than that of the control group ( P<0.05); the average levels of total cholesterol (TC), triglyceride (TG) and low density lipoprotein cholesterol (LDL-C) in serum decreased and high density lipoprotein cholesterol (HDL-C) increased significantly compared with that before exercise ( P<0.05～0.01), TG, LDL-C were also lower than that of the control group ( P<0.05). In the control group, only indexes of numbers of ischemia attacks, duration of ischemia attack and TG were lower than that in the first test ( P<0.05).ConclusionSquare physical fitness exercise can improve the indexes of disease conditions, biology and blood lipids.
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Objective To observe the therapeutic effect of spleen-invigorating and superficies-consolidating therapy combined with life style intervention for improving constitution of recurrent respiratory tract infection(RRTI) children.Methods One hundred and twenty RRTI children were classified into excessive yang with deficiency yin syndrome(N = 60) and excessive yin with deficiency yang syndrome(N = 60).Then the excessive yang with deficiency yin syndrome were equally randomized into herbal medicine group Ⅰ and western medicine group Ⅰ,and excessive yin with deficiency yang syndrome were equally randomized into herbal medicine group Ⅱ and western medicine group Ⅱ.Herbal medicine groups Ⅰ and Ⅱ were given Fuganning Oral Liquid and life style intervention,and western medicine groups Ⅰand Ⅱ were given thymic peptide capsules and life style intervention.Eight weeks constituted one treatment course.The score of symptoms before and after treatment,and the therapeutic effect were compared after 2 treatment courses.Results(1) The symptoms score was improved obviously in herbal medicine groups and western medicine groups(P 0.05).The difference of therapeutic effect was significant between both of herbal medicine groups(P