ABSTRACT
AIM: To delevop new drug delivery system for volatile oil of lignum dalbergia odoriferae and to improve its effect. METHODS: Solid-lipid-nanopaticals were prepared by hot-dispersiom technique and treated further by sonication; the contents of dispersion and entrapment efficiency of nanoparticles were determined by HPLC. RESULTS: Solid lipid nanoparticles containing volatile oil of lignum dalbergia odoriferae was spherelike; The partical size was 40.0nm; the content of dispersion was 72.1%; entrapment efficiency of nanoparticles was 91.27%. CONCLUSION: Solid-lipid-nanopatical may be a suitable drug delivery system for volatile oil of lignum dalbergia odoriferae.
ABSTRACT
Objective: To establish the GC fingerprinting of Lignum dalbergia odoriferae. Methods: The measurement conditions applied are as follows: DB 5 (0.32mm?30m 0.25?m) column; detector: FID; internal standard: tetradecyl alchohol. Results: Fingerprint of Lignum dalbergia odoriferae consisted of 7 peaks. The area of peaks exceeded 90% of total one. RSD of precision and reproducibility is in the range of 5%. Conclusion: The method can be used for quality control of Lignum dalbergia odoriferae.