ABSTRACT
Objective: Watermelon frost powder (WFP, Mirabilitum Praeparatum) is a Chinese patent drug commonly used for external application, consisting of dozens of Chinese materia medica. To determine the contents of the multi-components in WFP. Methods: Quantitative analysis of 10 principal constituents and three principal volatile constituents had been taken in this experiment to investigate the quality of Glycyrrhizae Radix, Coptidis Rhizoma, Phellodendri Cortex, Rhei Radix et Rhizoma, Scutellariae Radix, Borneolum, and menthol in WFP by HPLC and GC. Results: Comparing with raw materials, the contents of liquirtin and glycyrrhetinic acid were distinct, and the contents of rhein in WFP and raw Rhei Radix et Rhizoma were different. The possible reasons might lie in the input status of raw materials in the processes of production or others. In GC test, isoborneol, the constituent in Borneolum syntheticum, had been detected out, and should not exist in nature Borneolum. Conclusion: The inspection standard of WFP should be perfected and some weakness involved in this experiment requires further explanation and research. © 2014 Tianjin Press of Chinese Herbal Medicines.
ABSTRACT
Objective: To optimize the cutting technology for Glycyrrhiza uralensis. Methods: Using the contents and appearance characters of liquirtin and glycyrrhizic acid as indexes, the effects of different cutting methods, such as embellishing, steaming, and baking, on the quality of G. uralensis were investigated by Box-Behnken design-response surface method, so as to optimize the cutting technology parameters of G. uralensis. Results: The optimal parameters were as follows: embellishing time of 6 h, steaming time of 30 min, drying time of 2 h, and drying temperature of 60°C. Conclusion: The optimized cutting technology of G. uralensis is feasible.
ABSTRACT
OBJECTIVE: To study the chemical constituents of Ginkgo biloba kernel. METHODS: The chemical constituents were isolated by silica gel chromatography, and their structures were elucidated by physical-chemical and spectroscopic data. RESULTS: Nineteen compounds were isolated and their structures were identified as hexacosanoic acid (I), palmitic acid (II), ginnol(III), β-sitosterol (IV), 2, 3-dihydroxypropyl hexadecoate (V), ursolic acid(VI), sciadopitysin (VII), ginkgetin (VIII), isoginkgetin (IX), daucosterol(X), ginkdolide A (XI), ginkdolide B (XII), ginkdolide C (XIII), uracil(XIV), coniferin (XV), liquirtin (XVI), adenosine (VII), D-glucose (XVIII) and sucrose (XIX). CONCLUSION: Compounds VI, XV-XVII are obtained from this plant for the first time, compounds I-V, VII-X and XIV are obtained from Ginkgo biloba kernel for the first time. Copyright 2012 by the Chinese Pharmaceutical Association.