ABSTRACT
Objective:To investigate the application value of multi-slice spiral CT angiography in the diagnosis of pulmonary arteriovenous malformations.Methods: 11 cases of pulmonary arteriovenous malformation clinically diagnosed were given a retrospective analysis of our hospital in recent years through multi-slice spiral CT diagnosis. All patients had CT imaging to check data and surgical data.Results: CT pulmonary angiography found 10 cases were a single hair in 11 cases of pulmonary abnormalities and one case was more hair, which have 12 lesions in total.Conclusion:The multi-slice spiral CT pulmonary angiography technology becomes more mature. The use of multi-slice spiral CT pulmonary angiography and image post-processing techniques can improve the diagnosis of pulmonary arteriovenous malformation accuracy and detection rate, and can provide image data for clinical treatment.
ABSTRACT
OBJECTIVE: To investigate the correlation between radiologic vascular dilatation and serum nitrite concentration and eNOS expression in the endothelial cell and pneumocyte in a rabbit model of hepatopulmonary syndrome induced by common bile duct ligation (CBDL). MATERIALS AND METHODS: Thin-section CT scans of the lung and pulmonary angiography were obtained 3 weeks after CBDL (n=6), or a sham operation (n=4), and intrapulmonary vasodilatation was assessed. The diameter and tortuosity of peripheral vessels in the right lower lobe by thin-section CT and angiography at the same level of the right lower lobe in all subjects were correlated to serum nitrite concentration and eNOS (endothelial nitric oxide synthase) expression as determined by immunostaining. RESULTS: The diameters of pulmonary vessels on thin-section CT were well correlated with nitrite concentrations in serum (r = 0.92, p < 0.001). Dilated pulmonary vessels were significantly correlated with an increased eNOS expression (r = 0.94, p < 0.0001), and the severity of pulmonary vessel tortuosity was found to be well correlated with serum nitrite concentration (r = 0.90, p < 0.001). CONCLUSION: The peripheral pulmonary vasculature in hepatopulmonary syndrome induced by CBLD was dilated on thin-section CT and on angiographs. Our findings suggest that peripheral pulmonary vascular dilatations are correlated with serum nitrite concentrations and pulmonary eNOS expression.