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@#AIM:The repair of macular structure after 23G vitrectomy was performed in patients with idiopathic macular hole, and the changes of retinal thickness in vision and macular area were analyzed.<p>METHODS: A total of 85 patients(85 eyes)with monocular idiopathic macular hole who underwent elective surgery in our hospital from June 2016 to December 2017 were included in the study, of which 37 were male and 48 were female, with an average age of(64.7±10.1)years. All subjects underwent 23G vitrectomy were observed the closure of macular hole after operation, and the changes of retinal thickness in macular forea were observed preoperatively and postoperatively by optical coherence tomography(OCT). To observe the changes of the best corrected visual acuity(BCVA)in preoperative, 1mo, 3mo and 6mo after operation.<p>RESULTS: All subjects underwent postoperative examinations had good macular hole closure. The average BCVA of 3mo and 6mo after operation were significantly higher than that of preoperative and 1mo after operation(<i>P</i><0.05); the average BCVA in 6mo after operation was significantly higher than the average BCVA of 6mo after operation, with statistically significant differences(<i>t</i>=7.983, <i>P</i>=0.037). The macular central fovea thickness in 1mo after operation was significantly higher than preoperative and 3mo, 6mo after operation(<i>P</i><0.05); The retinal thickness of the macular fovea thickness in 3mo and 6mo after operation were significantly lower than that of preoperative.<p>CONCLUSION:The treatment of idiopathic macular hole with 23G vitrectomy had a high degree of successful closure rate of fracture hole and the visual acuity of patients was obviously improved.
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PURPOSE: To analyze the recovery course of foveal microstructures and evaluate the important structures for visual improvement after vitrectomy for full thickness macular hole (MH) using optical coherence tomography (OCT). METHODS: We retrospectively reviewed the medical records of 34 cases with idiopathic macular hole. We investigated the healing process of foveal microstructures and visual acuity pre- and post-operatively at 1, 3, 6, 12 months after surgery. We evaluated the integrity of four factors by OCT image: existence of MH (Hole, H(1,3,6,12)), recovery of outer nuclear layer (ONL, O(1,3,6,12)), recovery of external limiting membrane (ELM, E(1,3,6,12)), and recovery of inner segment-outer segment (IS/OS) line of the photoreceptor (Photoreceptor, P(1,3,6,12)). We compared the recovery course and visual acuity of the four groups based on postoperative 12 months. RESULTS: The mean observed period was 1.85 ± 2.59 months at recovery of ONL, 3.78 ± 3.83 months at recovery of ONL and ELM, and 7.40 ± 3.56 months at recovery of ONL, ELM and IS/OS line. At postoperative 12 months, the best corrected visual acuity (BCVA) of Groups E and P were better than that of Groups H and O (p < 0.05). Except for group H, all groups had improved BCVA at postoperative 12 months compared to preoperative BCVA (p < 0.05). CONCLUSIONS: Recovery sequences of foveal microstructures were ONL, ELM and IS/OS line after vitrectomy for idiopathic MH. The most important structures for visual acuity were restorations of both ELM and IS/OS line.
Subject(s)
Medical Records , Membranes , Retinal Perforations , Retrospective Studies , Tomography, Optical Coherence , Visual Acuity , VitrectomyABSTRACT
AIM: To measure the macular structure of amblyopia eyes and non-amblyopia eyes in children with monocular hyperopic amblyopia and in normal children by optical coherence tomography (OCT). METHODS: Fifty-six children with monocular hyperopic amblyopia and 75 normal children were selected. The macular retinal thickness and the macular retinal volume were measured by OCT. Data was used for statistical analysis. RESULTS: The thinnest part of retina was at the center retina, and the thickest part was the inner ring , while the outer ring was thinner than the inner ring in the amblyopia eyes group. Among the four quadrants of the inner ring, the thickest quadrant was the nasal quadrant (335. 58 ± 17. 42μ m) , and the thinner part was superior quadrant (326. 42 ± 15. 36μ m), the next was the inferior quadrant ,the thinnest part was the temporal quadrant. The trend of outer ring was the same as the inner ring. The quadrant differences of non - amblyopia eyes and normal eyes were same with amblyopia eyes. The center 1mm of macula, nasal quadrant and superior quadrant retinal thickness of inner ring were thicker in amblyopia eyes group than that in non- amblyopia eyes group and normal eyes group ( P 0. 05). The other quadrant retinal thickness was not different in amblyopia eyes group, non- amblyopia eyes group and normal eyes group (P> 0. 05). In amblyopia eyes group, non- amblyopia eyes group and normal eyes group, the smallest retinal volume was macular retinal volume, the biggest volume was nasal retinal volume of inner ring, then was superior retinal volume and inferior retinal volume ,the smallest was temporal retinal volume. The change of retinal volume in outer ring was same as inner ring. The difference of central 1mm macular retinal volume, nasal quadrant and superior quadrant retinal thickness of inner ring in amblyopia eyes group was statistically significant compared with non - amblyopia eyes group and normal eyes group (P0. 05). CONCLUSION: OCT can accurately measure macular retinal structure, the difference of macular retinal structure between amblyopia eyes, non - amblyopia eye and normal eyes may be associated with the peripheral mechanism of amblyopia.
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PURPOSE: To present preoperative macular structure deformities and surgical outcomes in idiopathic epiretinal membrane (ERM) patient according to the presence of vitreomacular traction syndrome (VMTS). METHODS: This retrospective observational study included 54 eyes of 51 patients with idiopathic ERM, who underwent pars plana vitrectomy with ERM and internal limiting membrane (ILM) peeling, and were followed for more than 6 months. Subjects were classified into 2 groups according to the presence of VMTS using preoperative optical coherence tomography (group 1: ERM without VMTS, 29 eyes; group 2: ERM with VMTS, 22 eyes). Preoperative macular structure deformity and surgical outcomes were compared and prognostic factors were analyzed. RESULTS: Group 1 (ERM without VMTS) included 29 eyes, and group 2 (ERM with VMTS) included 22 eyes. Group 2 had a significantly higher occurrence of lamellar macular hole and a significantly lower preoperative best-corrected visual acuity (BCVA) compared to group 1. However, final postoperative BCVAs were not significantly different between the groups because BCVA changed more in group 2. Preoperative macular structure deformities (irregular retinal surface, retinal thickening, lamellar macular hole, and cystoid macular edema) did not affect visual outcomes. The presence of photoreceptor inner segment/outer segment (IS/OS) junction disruption and preoperative BCVA were highly related with visual outcomes. CONCLUSIONS: BCVA significantly improved in idiopathic ERM patients who underwent pars plana vitrectomy with ERM and ILM peeling regardless of the presence of VMTS. There may be a stronger association of IS/OS junction disruption with visual acuity compared to VMTS in idiopathic ERM surgery.
Subject(s)
Humans , Congenital Abnormalities , Epiretinal Membrane , Membranes , Observational Study , Retinal Perforations , Retinaldehyde , Retrospective Studies , Tomography, Optical Coherence , Traction , Visual Acuity , VitrectomyABSTRACT
PURPOSE: To present preoperative macular structure deformities and surgical outcomes in idiopathic epiretinal membrane (ERM) patient according to the presence of vitreomacular traction syndrome (VMTS). METHODS: This retrospective observational study included 54 eyes of 51 patients with idiopathic ERM, who underwent pars plana vitrectomy with ERM and internal limiting membrane (ILM) peeling, and were followed for more than 6 months. Subjects were classified into 2 groups according to the presence of VMTS using preoperative optical coherence tomography (group 1: ERM without VMTS, 29 eyes; group 2: ERM with VMTS, 22 eyes). Preoperative macular structure deformity and surgical outcomes were compared and prognostic factors were analyzed. RESULTS: Group 1 (ERM without VMTS) included 29 eyes, and group 2 (ERM with VMTS) included 22 eyes. Group 2 had a significantly higher occurrence of lamellar macular hole and a significantly lower preoperative best-corrected visual acuity (BCVA) compared to group 1. However, final postoperative BCVAs were not significantly different between the groups because BCVA changed more in group 2. Preoperative macular structure deformities (irregular retinal surface, retinal thickening, lamellar macular hole, and cystoid macular edema) did not affect visual outcomes. The presence of photoreceptor inner segment/outer segment (IS/OS) junction disruption and preoperative BCVA were highly related with visual outcomes. CONCLUSIONS: BCVA significantly improved in idiopathic ERM patients who underwent pars plana vitrectomy with ERM and ILM peeling regardless of the presence of VMTS. There may be a stronger association of IS/OS junction disruption with visual acuity compared to VMTS in idiopathic ERM surgery.