ABSTRACT
Objective: To study the chemical constituents of the stems and leaves of mangrove plant, Scyphiphora hydrophyllacea. Methods: The chemical constituents of S. hydrophyllacea were separated and purified by silica gel, ODS, Sephadex LH-20 gel column chromatographies and preparative HPLC. Their structures were identified by physicochemical properties, spectroscopic analysis, as well as comparisons with the data reported in literatures. Results: A total of 18 compounds were isolated from the 90% ethanol extract of the stems and leaves of S. hydrophyllacea, which were identified as pomonic acid (1), euscaphic acid (2), dammaradienyl acetate (3), erythrodiol (4), lupenyl acetate (5), 30-oxo-lupeol (6), maslinic acid (7), 23-hydroxyursolic acid (8), β-amyrenone (9), acacetin (10), chrysoeriol (11), jaceosidin (12), kumatakenin (13), isosakuranetin (14), taxifolin (15), lyoniresinol (16), medioresinol (17), and balanophonin (18). Compounds 1-9 were triterpenoids, compounds 10-15 were flavonoids and compounds 16-18 were lignans. Conclusion: All compounds are isolated from the genus Scyphiphora for the first time.
ABSTRACT
Mangroves are salt-tolerant forest ecosystem that extends between tropical and subtropical intertidal regions of the world. Mangroves are biochemically unique vegetation that produce wide array of natural products with immense medicinal potential. These plants are the most valuable resources and provide economic and ecological benefits to the coastal people. Natural products from these plants are of great interest as they provide innumerable direct and indirect benefits to human beings for the discovery of novel antimicrobial and other bioactive compounds. They possess active metabolites with some novel chemical structures that belong to diverse chemical classes such as alkaloids, phenol, steroids, terpenoids and tannins. Several mangrove species have been used in traditional medicine or have few applications as insecticide and pesticide. To date, several mangroves, and their associated species and solvent extracts are screened for antimicrobial activity along with the presence of potent bioactive compounds. The present article emphasizes and creates awareness about the potential mangrove plants and their associates as a source of biologically active compounds with potent antimicrobial properties. This paper also elaborates the mechanisms of action and various methods for screening of antimicrobial compounds.
Subject(s)
Anti-Infective Agents , Pharmacology , Avicennia , Chemistry , Ecosystem , Plant Extracts , PharmacologyABSTRACT
Objective To investigate the chemical constituents in the aerial parts of mangrove plant Avicennia marina. Methods The isolated compounds Ⅰ-Ⅹ were obtained by the combination of silica gel, Sephadex LH-20 column chromatographies and by semi-preparative HPLC separation. Structural elucidation was conducted by the modern spectral method. Results Ten compounds were isolated and identified from the aerial parts of A. marina, including acteoside (Ⅰ), isoacteoside (Ⅱ), syringaresinol (Ⅲ), 5, 7-dihydroxy-3′, 4′, 5′-trimethoxyflavone (Ⅳ), indolyl-3-carboxylic acid (Ⅴ), betulinic acid (Ⅵ), betullin (Ⅶ), lupeol (Ⅷ), avicequinone C (Ⅸ), and kaempferol (Ⅹ). Conclusion Compounds Ⅰ-Ⅵ are isolated from A. marina for the first time.