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Background: In the developing world Nutritional deficiency anaemia is the commonest finding in pregnant women. Lack of balanced diet, poor socio-economic status, repeated pregnancies and illiteracy are seen associated with Anaemia commonly. Anaemia itself results in maternal morbidities and poor pregnancy outcomes. Neonatal morbidities also have a direct equation with anaemia. It is a study done on pregnant women in labour with the sole objective to estimate the prevalence of anaemia amongst them and associated fetomaternal morbidities.Methods: It is a prospective observational study done on 300 pregnant women presenting in labour from October 2019-Decemebr 2019, in Government Doon Medical College, Dehradun. These women belonged to Dehradun and surrounding hilly areas of Uttarakhand. Their haemoglobin levels (complete blood count) were assessed at the time of admission along with other routine investigations. They were also assessed for associated pre and post-delivery morbidities and mortality.Results: In this study, out of 300 pregnant women presenting in labour from October 2019 to December 2019, in Government Doon Medical College Dehradun, the incidence of anaemia was found to be very high (70%). Severely anaemic patient group was found to have maximum number of fetomaternal complications and blood transfusion requirements.Conclusions: Despite all the maternal welfare programmes being run at National levels, it is being observed that there is a high unacceptable prevalence of anaemia in pregnant women. This increases their morbidity and mortality. It is a huge burden on hospital finances and blood bank for blood transfusions which are preventable. There is need to strengthen our health care system at primary level for pregnant women and teenage girls.
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Background: Anaemia is the commonest medical disorder in pregnancy and has a varied prevalence, etiology and degree of severity in different populations. The purpose of this study was to evaluate the prevalence of maternal anaemia in pregnancy and its impact on perinatal outcome.Methods: This was a prospective observational study conducted in department of obstetrics and gynecology JLN Hospital Ajmer, Rajasthan, India from October 2015 to December 2016. Total 325 pregnant women were included in the study who fulfilled the inclusion criteria and found to have moderate to severe anaemia.Results: Prevalence of anaemia in pregnancy was 80% in present study. Perinatal mortality was 13.3% in moderate anaemia and in severe anaemia 42%. In present study maximum 56% of cases were in the age group of 20-25 years, and maximum number of cases were primigravida (33.84%). Out of 225 cases of moderate anaemia only 50 cases (22.22%) had antenatal check-up once or twice. Out of 225 cases of moderate anaemia, 66.66% cases were rural and 33.33% cases were of urban group. Fetal outcome in present study was in form of 49.23% premature birth with 33.12% perinatal mortality.Conclusions: Maternal anaemia in pregnancy is associated with illiteracy, low socioeconomic status, multiparity, inadequate antenatal care and rural geographic area. Severe anaemia was associated with high perinatal mortality.
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Background: There is a large body of research both in India and abroad studying the effect of maternal age, parity and haemoglobin (in third trimester) on their infant’s birth weight. The present study has been planned to evaluate these factors effects on their infant’s stature(anthropometry) and cord blood haemoglobin.Methods: Maternal background information, third trimester haemoglobin concentration, gestational age and number of children was obtained and recorded in semi-structured case proforma. 100 post-partum women and their newborns were studied in post-natal ward of a tertiary care hospital in an urban area. Maternal and neonatal data and anthropometric measurements were recorded in semi-structured case proforma.Results: Of the 100 newborns, 43% were second born, followed by 35% first born, 18% third born and only 4% were fourth born by the order of their birth. Out of the 100 studied mothers 52% were anaemic as per the WHO criteria (Hb <11 gm%). Cord blood haemoglobin values decreased significantly as the order of birth increased. The cord blood haemoglobin of normal birth weight newborns is significantly higher as compared to that of low birth weight newborns. Cord blood haemoglobin concentrations shows strong statistical significance with maternal anaemia. The birth order of the child has a prominent inverse effect on the cord blood haemoglobin values.Conclusions: There should nationwide improvement in the nutritional status of the girl child by dietary supplementations to improve the health of the generations to come. There should be proper birth spacing to prevent maternal and neonatal morbidities. Maternal anaemia needs early and aggressive treatment to minimize perinatal complications to both mother and the baby.
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Background: Thrombocytopenia (platelet count <1,50,000/'L) is one of the most common haematological problems in neonatal intensive care units. In contrast, only 2% of the normal neonates are thrombocytopenic at birth with severe thrombocytopenia (platelet count <50,000/'L) occurring in less than 3/1000 term infants. Multiple disease processes can cause thrombocytopenia in neonates. The important causes of thrombocytopenia in neonates are sepsis, birth asphyxia, prematurity, intra-uterine growth retardation, hyperbilirubinemia, respiratory distress syndrome, meconium aspiration syndrome and low birth weight. Apart from platelet count, bleeding manifestations depend on underlying ailments. The aims and objective were to study the clinical profile, etiology and outcome of neonatal thrombocytopenia in a tertiary care hospital.Methods: Prospective study involving 100 neonates with or developed neonatal thrombocytopenia in NICU.Results: In present study, 100 new-borns with thrombocytopenia 46% were mild, 35% were moderate and 19% were severe thrombocytopenia. 51 (51%) had early onset neonatal thrombocytopenia and 49 (49%) babies had late onset neonatal thrombocytopenia. Anaemia was the dominant maternal predisposing risk factor. Sepsis was the most common cause of neonatal thrombocytopenia. Most common symptom was apnoea. Sepsis, RDS and NEC had significantly contributed to mortality. Most common cause of death was sepsis followed by RDS and NEC.Conclusions: Neonatal thrombocytopenia is a treatable and reversible condition. Hence, it is important to identify neonates at risk and initiate transfusion therapy to prevent severe bleeding and potentially significant morbidity. Anaemia and PROM were the commonest maternal risk factors. Therefore, author recommended that babies born to mothers with these risk factors should be closely monitored for thrombocytopenia.
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Background: Anaemia during pregnancy is associated with serious maternal and fetal complications. Cord blood hemoglobin of the newborn is an important indicator of anaemia in newborn at birth. So, this study is done to assess the impact of maternal anaemia on cord blood hemoglobin levels of neonates.Methods: It is a cross sectional study done at government Kilpauk medical college and hospital in the department of paediatrics in year 2016.400 pregnant mothers attending the labour room in Kilpauk medical college were included and cord blood haemoglobin of their babies were collected. Mean cord blood haemoglobin of new-borns born to anaemic mothers (mild, moderate and severe) were compared with cord blood haemoglobin of new-borns born to non-anaemic mothers.Results: Out of 400 mothers,192 mothers were anemic, and 208 mothers were non anemic. The mean maternal hemoglobin among non-anemic mothers was 16.37'0.85 and among the anemic mothers it was 15.03'1.04. The mean cord hemoglobin of neonates born to anemic mothers among the three groups (mild moderate severe) were compared with mean cord hemoglobin of the non-anemic group. The difference between groups were statistically significant with P values <0.05,0.01 and 0.05 respectively.Conclusions: In present study maternal anaemia affects the cord blood haemoglobin of neonates. Present study infers that anaemic mothers deliver babies with lower haemoglobin compared to non-anaemic mothers. Authors have found a linear relationship between maternal haemoglobin and cord blood haemoglobin of the new-borns.
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Background: Anaemia in pregnancy remains a major health problem with adverse maternal and fetal outcome worldwide, especially in developing countries such as Tanzania. The study aimed to establish prevalence and obstetric factors associated with anaemia among pregnant women attending antenatal care visits in Unguja Island, Tanzania.Methods: This cross sectional survey used systemic random sampling in three hospitals of Unguja Island to select 388 pregnant women. Demographic and obstetric characteristics of respondents were collected using a structured questionnaire. Hemoglobin levels were measured by using Hemocue machine. Multivariate logistic regression analysis was carried out in SPSS version 21.0 to measure obstetric factors associated with anaemia among pregnant women.Results: The overall prevalence of anaemia among pregnant women was 80.8%, whereby 68.64% of respondents had mild anaemia, 11.24% had moderate anaemia and 0.89% had severe anaemia. The factors associated with anaemia in pregnancy were gravidity, (AOR= 1.185, 95% CI=0.317-4.338, p<0.001), irregular taking of iron tablets (AOR=0.288, 95% CI=0.149-0.556, p<0.001) and age of the child <2 years, (AOR 3.635, 95% CI= 1.103-11.882, p<0.034).Conclusions: The prevalence of anaemia among pregnant women in Unguja is high. Timely and regular intake of iron tablets during pregnancy, child spacing as well as having children within the capacity of parents to raise them up may significantly reduce the prevalence of anaemia in pregnancy. Therefore health education on family planning and the importance of taking of iron tablet is critical.
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Context: Anaemia is a common pregnancy related disorder in Bangladesh that causes various maternal and fetal problems. A prospective study was designed to see the associated maternal factors and fetal outcome in different categories of anaemia and to compare with that of normal pregnancy. Methods: The study was carried out on 60 Bangladeshi women within 35-40 weeks of gestation. Among them, 20 with normal uncomplicated pregnancies were considered as control group or group A, another 27 having pregnancies with mild anaemia were considered as group B, and 13 having pregnancies with moderate anaemia were considered as group C. Severe anaemic mothers were considered as group D, but not found during the period of collection of data for this study. The mothers were selected as who were suffering from antenatal anaemia i.e. having heamoglobin level <10 gm/dl (mild, if <10 gm/dl; moderate, if <8 gm/dl; and severe, if <6 gm/dl) and control i.e. having heamoglobin level ≥10 gm/dl. The foetal outcome was observed and recorded after delivery. Results: The mean age of the mother was 23.65±3.83 years, 27.26±4.93 years and 25.85±4.62 years and the mean number of gravidity was 1.65±0.67, 2.15±0.72 and 2.69±1.03 in group A, group B and group C respectively. The difference was statistically highly significant in between A and C (p<0.001) and also significant in between A & B and B & C (p<0.05). The mean gestational age of the mother was 38.65±0.88 weeks, 37.37±1.01 weeks and 37.15±1.28 weeks in group A, group B and group C respectively and the difference was statistically significant between A & B and A & C (p<0.001). The mean birth weight of the neonate was 3.09±0.30 Kg., 2.99±0.16 Kg. and 2.95±0.21 Kg., while the mean APGAR score of the neonate at first minute of birth was 8.90±1.07, 8.11±0.89 and 7.69±0.48 in group A, group B and group C respectively. No significant difference was found in birth weight of the newborn babies in between the groups of the mothers. However, the difference was found significant in between A & B (p<0.01) and A & C (p<0.001), in case of APGAR score.