Maternal anemia in various trimesters of singleton pregnancies and its correlation with birth weight: An observational study

Background: Anemia is a very important preventable nutritional disorder affecting pregnant ladies which may have some adverse effects on the neonatal survival and development. Birth weight was correlated with changes in maternal hemoglobin concentration in various trimesters as it is important for determining child survival and development. Aims and Objectives: The aim of the study was to assess the correlation between maternal hemoglobin levels in various trimesters and neonatal birth weight. Materials and Methods: The study enrolled all pregnant women within age group 15–35 years who gave birth at Agartala Government Medical College and GBP Hospital from June 15, 2017 to August 15, 2017. Pregnant women were included into the study following delivery by simple random sampling into cases (Pregnant women who delivered low birth weight babies <2500 g) and control group (Pregnant women who delivered normal birth weight babies ?2500 g). Antenatal data were collected from hospital case sheet and labor room register. Data were analyzed using descriptive statistics and presented as Mean + SD. P < 0.05 (P < 0.05) was considered statistically significant. Results: Mean hemoglobin concentration was normal (?11 g/dl) in all three trimesters among the controls but it is found to be <11 g/dl in second and third trimesters of the case group. The mean birth weight of the babies was 2.151(± 0.2386) kg in case group and 3.047(± 0.3666) kg in control group. Conclusions: It was found that maternal hemoglobin concentration has a positive correlation (r > 0) with neonatal birth weight in all three trimesters in both cases and controls which is statistically significant (P < 0.05).

Relationship between maternal hemoglobin and birthweight in Antioquia, Colombia / Relación de la hemoglobina materna y el peso al nacer en Antioquia-Colombia

Abstract Objectives: to determine the relationship between maternal hemoglobin (HbM) per gestational trimester and birthweight (BW). Methods: this was an analytical, cross-sectional observational study that included the prenatal records of494 pregnant women who delivered live newborns in the Department of Antioquia. The maternal health data collected included HbM and BW, and gynecological and obstetric, anthropometric, and maternal health-related data. The Mann-Whitney U test was applied, supplemented by effect size (ES) to compare the study groups. Results: HbMin the third trimester was significantly associated with BW (p=0.029).It showed a significant effect size on BW as follows: first trimester: ES=0.44 (CI95%= 0.183-0.697); second trimester: ES=0.49 (CI95%= 0.187-0.79); and third trimester: ES=0.43 (CI95% = 0.202-0.658). Maternal anemia was 4.2%>, 11.2%, and 21.4%> in the first, second, and third trimester, respectively. Conclusions: as it is an inexpensive indicator and easy to determine, the timely monitoring and assessment of HbM is required owing to its importance in maternal and neonatal health, quality of life, and human capital development.

Resumen Objetivos: determinar la relación entre hemoglobina materna (HbM) por trimestre de gestación y peso al nacer (PN). Métodos: estudio observacional analítico, transversal, en 494 historias prenatales de gestantes con recién nacido vivo del departamento de Antioquia. Se tomaron datos de HbMy PN, ginecobstétricos, antropométricos y de salud materna. Para comparar los grupos de estudio, se aplicó la prueba U-Mann Whitney, complementada con el tamaño de efecto (ES). Resultados: la HbM de tercer trimestre se asoció significativamente con el PN (p=0,029); la HbM mostró un tamaño de efecto importante sobre el PN, así: primer trimestre: ES=0,44 (IC95%= 0,183 a 0,697); segundo trimestre: ES=0,49 (IC95%= 0,187 a 0,79); tercer trimestre: ES=0,43 (IC95%o= 0,202 a 0,658). La anemia materna fue 4,2°%, 11,2%o y 21,4°% en el primero, segundo y tercer trimestre, respectivamente. Conclusiones: Se necesita seguimiento y evaluación oportuna de la HbM, indicador de bajo costo y fácil determinación, por su importancia en la salud materna y neonatal, en la calidad de vida y desarrollo del capital humano.

Effects of Oral administration of Iron Supplements During Pregnancy on Maternal Hemoglobin Levels and Birth Weights / 대한산부인과학회잡지

OBJECTIVE: This study was performed to evaluate the effects of oral administration of iron supplements during pregnancy on maternal hemoglobin concentrations and birth weights. METHOD: Data from clinical records of 141 pregnant women and their babies were analysed. Studied mothers were classified to 3 groups such as non iron supplement group (groupI), 2-3 months supplement group (group II), and over 4 months supplement group (group III) by the duration (months) of oral supplement prescribed. RESULTS: There was positive correlation between hemoglobin levels and iron supplement duration. Proportions of anemia showed decreasing basis with the increasing iron supplement duration. The maternal hemoglobin levels showed decreasing basis with the increasing birth weight. There was positive correlation between iron supplement duration and maternal hemoglobin levels, but there was no significant correlation between iron supplement duration and birth weight. For the groupI(non-supplement group), maternal hemoglobin levels were decreased with the increasing birth weight but there was no significant correlations between hemoglobin levels and birth weights with increased iron supplement duration. CONCLUSION: There was a significant inverse correlation between maternal hemoglobin levels and birth weight in non-iron supplement group but there was no significant correlations between hemoglobin levels and birth weights with increased iron supplement duration.

Relationship between Maternal Hemoglobin Concentration and Birth Weight of Newborns

High matemal hemoglobin levels have been associated with intrauterine growth retardation and preterm delivery. We used it to examine the relationship between the lowest hemoglobin concentration in pregnancy, birth weight of newborns and preterm delivery. The study included 2586 pregnancies. The result as follows. A group with higher hemoglobin(above 14.5 g/dL) levels during pregnancy has higher incidence of low birth weight and preterm delivery than norrnal or low maternal hemoglobin levels.