ABSTRACT
Objective: To study the chemical constituents in 60% ethanol extract from the aerial parts of Matteuccia struthiopteris. Methods: Diaion HP20 macroporous adsorption resin column chromatography (CC), silica gel CC, ODS CC, Sephadex LH-20 CC, and PHPLC were used for the isolation and purification. Structures were identified on the basis of chemical evidences and spectroscopic analyses. Results: Twelve compounds were isolated and identified as 4,7-megastigmadiene-3,9-diol (1), blumenol A (2), dehydrovomifoliol (3), bridelionol F (4), bridelionol B (5), 3,5,6-trihydroxy-7-megastigmen-9-one (6), 5β,6α-dihydroxy-3β-(β-D- glucoyranosyloxy)-7-megastigmen-9-one (7), byzantionoside A (8), dearabinosyl pneumonanthoside (9), 3-hydroxy-β-damascone glucoside (10), amarantholidoside IV (11), and icariside C3 (12). Conclusion: Compounds 1-12 are reported from the plants of Matteuccia Todaro for the first time.