ABSTRACT
Algunos estudios han intentado evaluar la capacidad de la Escala de Demencia de Mattis (MDRS) para detectar demencia incipiente o Deterioro Cognitivo Leve(DCL), pero los resultados no son claros. El objetivo de este estudio fue evaluar la sensibilidad y especificidad de la MDRS para detectar DCL, y localizar el puntaje de corte más adecuado para la población local. Metodología. Una batería neuropsicológica que incluyó la MDRS fue aplicada a 60 adultos mayores de ambos sexos (edad media=68.38, DE=6.80) en Córdoba, Argentina, quienes fueron clasificados según su estado cognitivo en Normales (34 casos) o DCL (26 casos) según su desempeño en la batería neuropsicológica administrada, excluyendo la puntuación en la MDRS. El criterio empleado fue el de la Sociedad Española de Neurología. Se realizaron comparaciones de medias y un análisis de regresión logística para evaluar la capacidad del MDRS para diferenciar ambos grupos y localizar el puntaje de corte. Resultados. Aunque la MDRS diferenció ambos grupos a partir de la media (p=.004), la precisión diagnóstica fue sólo del 63 por ciento al utilizar un puntaje de corte total de 133. La sensibilidad fue del 42 por ciento y la especificidad fue del 79 por ciento. Conclusiones. El MDRS no parece ser una herramienta útil para detectar DCL, ya que presenta numerosos casos mal clasificados. El desarrollo de herramientas más adecuado para detectar DCL resulta fundamental...
Some studies have tried to assess the Mattis Dementia Rating Scale (MDRS) capability to detect incipient dementia or Mild Cognitive Impairment (MCI), but the results are not clear. The aim of this research was to evaluate the sensitivity and specificity of the MDRS, and to localize the optimal cutoff score for MCI. Methodology. A neuropsychological battery that included the MDRS was administered to 60 older adults of both genders (Mean age=68.38, SD=6.80) in Córdoba, Argentina, who were then classified as Control (34 cases) or MCI (26 cases) according to performance in the neuropsychological evaluation, excluding the MDRS. The criteria used were those stated by the Sociedad Española de Neurología. We performed mean comparisons in order to evaluate if the MDRS was able to detect the group differences. Then, a logistic regression with the MDRS total score as the predictor variable and the group as the criterion variable was performed to determine the cutoff score. Results. Even though the mean comparisons showed a significant difference in the MDRS (p=.004), the diagnostic accuracy was only 63 percent with a 133 points cutoff score. The sensitivity was 42 percent and the specificity was 79 percent. Conclusions. The MDRS does not seem to be a useful tool to detect MCI since it generates numerous misclassified cases. The development of more accurate tools becomes fundamental in order to detect MCI...
Subject(s)
Humans , Male , Adult , Female , Dementia/diagnosis , Cognitive Dysfunction/diagnosis , Neuropsychological Tests , Logistic Models , Psychiatric Status Rating Scales , Sensitivity and SpecificityABSTRACT
Objective:To compare the cognitive functions between elderly of Shanghai, Hong Kong and San Diego.Method:104 elderly in Shanghai was evaluated by the Chinese version of Mattis Dementia Rating Scale (DRS)and mini-mental state examination (MMSE), the results were compared with that of 104 persons in Hong Kong and 150 elderly participants in San Diago.Result:Compared with Hong Kong participants, Shanghai participants performed significantly higher on one item, but there were significantly differences in five items between Shanghai participants and the San Diego participants which age and education were matched.Conclusion:Some DRS subscales or individual items may be susceptible to cultural differences.
ABSTRACT
Objective:To assess clinical validity of the Chinese version of Mattis Dementia Rating Scale (DRS) in differentiating dementia of Alzheimer type (AD). Methods:Administered the DRS, mini-mental state examination (MMSE) and clinical dementia rating(CDR) to 61 outpatients with AD and 104 healthy elderly subjects in Shanghai.Results:There was significant correlation between DRS and the total score,and DRS and MMSE.DRS of the AD group had significant correlation with CDR.Its significant correlation with CDR suggested satisfactory concurrent validity of the scale. The optimal DRS cutoff score for AD according to education level revealed a sensitivity of 85%～94% and a specificity of 90%～94%.Conclusion:The DRS is a clinically valid test for the detection of AD and its severity of cognitive impairment.