ABSTRACT
Background: Misuse and overuse of antimicrobials in intensive care units is of particular concern as it creates selective evolutionary pressure and thereby enables antimicrobial resistant bacteria to increase rapidly resulting in loss of antimicrobial effectiveness. The aim of the present study was to evaluate influence of Reserve Antimicrobial Indent form in Strengthening the antimicrobial stewardship in intensive care unit of tertiary care hospital, Rajasthan. Methods: An observational study was conducted over a period of 18 months, and the data was obtained from MRD and from the ICU after introduction of reserve antimicrobial indent form, of a tertiary care hospital. All the data was tabulated in summery sheets and were analyzed by using computer software SPSS version 20 and Microsoft Excel 2019. Results: A total 257 cases were reviewed during the study period, among these 46.77% were males and 53.23% were females in MRD group, out of 124 cases and 53.38% were males and 46.62% were females in MICU group, out of 133 cases. Total number of reserve drug prescribed was 444 out of which in MRD group Amoxicillin /Clavulanic acid were commonly prescribed followed by piperacillin/tazobactumand in ICU group Meropenem were commonly prescribed followed by piperacillin/tazobactum. Conclusions: Study showed reducing trend in overall consumption of reserve antimicrobial drugs, which also gave an overview of antimicrobial consumption pattern in intensive care unit.
ABSTRACT
Objectives: To study the drug utilization pattern in Medical Intensive Care Unit (MICU) in a tertiary care teaching hospital in rural area of Maharashtra. Materials and Methods: It was a retrospective and observational study, conducted during the period of March, 2013 to August 2013. Data was obtained through the prescription record of 123 patients admitted in the Medical ICU in the hospital from Medical Record Department (MRD) of the hospital. The study was conducted after obtaining permission from the Institutional Ethics Committee (IEC) of the college. Data was analyzed for- Most common causes for admission to MICU, male and female admission ratio, average number of drugs prescribed per prescription, Outcome of the patients, percentage usage of various antimicrobial groups. Results: Most common cause for admission in MICU was found to be Myocardial Infarction (MI) followed by angina. In all diseases number of male patients was found to be more than female patients. Average no of drugs per patients was found to be 7.82, Improvement was seen in 87.23% patients and mortality was seen in 2.23% patients. While condition remained same in 10.54% patients at the time of discharge. Cephalosporins were the most commonly prescribed antimicrobial group (65.33%) followed by aminoglycosides.