ABSTRACT
Objective:To observe the effect of Zikun decoction (ZKD) in treatment of Yin deficiency and blood dryness in delayed menorrhea due to decreasing ovarian reservation．Method:A total of 60 cases were randomly divided into two groups．The observation group was given ZKD orally，and the control group was treated with complex packing estradiol tablets/estradiol and dydrogestero for three months．The control group began to take medicine on the first day of menstruation for 28 days, while the observation group began to take medicine on the fifth day of menstruation, and stopped taking medicine on the first day of the next menstruation. Three menstrual cycles were followed up. The clinical syndrome scores, follicle-stimulating hormone (FSH), luteinizing hormone (LH), inhibin B (INHB), FSH/LH, Estradiol (E2), anti-müllerian hormone (AMH), and antral follicle count (AFC) scores of the patients before and after treatment were compared.Result:After treatment, there was no significant difference in clinical efficiency between observation group and control group, but the traditional Chinese medicine syndrome score of observation group was significantly reduced (P<0.05), observation group and control group had the same curative effect in improvement of FSH, FSH/LH, AMH and AFC (P<0.05), but ZKD was better than complex packing estradiol tablets/estradiol and dydrogestero in improvement of INHB.Conclusion:ZKD has a good treatment effect in the treatment of DOR. It can effectively improve patients' sex hormone levels, increase antral follicle count, improve the ovarian reserve function and promote menstruation.
ABSTRACT
Background: The knowledge of the proper use, disposal of sanitary pads, and its related side effects during menstruation is a vital aspect of a woman’s well-being. Use of sanitary pads appropriately and replacing them on time are essential practices needed to maintain menstrual hygiene. Failure to do so may lead to detrimental consequences that could affect the health of women and make them susceptible to reproductive tract infections. Objectives were to assess a range of factors considered by female about the usage of sanitary pads and the various methods employed regarding its disposal.Methods: A cross sectional study was conducted from March to June 2018, in the city of Karachi, by students of Jinnah Sindh Medical University. A sampling technique was used to select 391 females. Data collection was carried out using a structured questionnaire, by convenience sampling. Response of the participants was acquired using a 5-point Likert scale.Results: In total, 391 females from the city took part in this study; their ages ranging between 15-45 years. 95.7% of these females preferred sanitary pads over cloth, tampons, menstrual cups and toilet paper. Many women using sanitary pads believed, pads should be replaced often while menstruating and failure to do so may increase the risk of contracting infections (p≤0.01).Conclusions: The findings showed that a significant number of women are aware of the risks associated with sanitary napkins and have adequate knowledge related to its proper usage. The study also presented no significant risk of adverse effects associated with the use of sanitary pads.