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Aims: We previously demonstrated that a blend of herbal extracts (Weighlevel®; a mixture of extracts from the leaves of Alchemilla vulgaris, Olea europaea, Mentha longifolia and from the seeds of Cuminum cyminum) taken 3 times per day produces weight loss in preclinical and clinical studies. The aim of the present study was to test the efficacy of a new slow-release formulation (Weighlevel® One) taken once per day on change in body weight and related measures. Study Design: Randomized, double-blind, placebo-controlled study. Place and Duration of Study: Health Clinics in Copenhagen, Denmark between 7 January 2016 and 5 March 2016. Methodology: Thirty-six adult subjects were randomized to consume the herbal blend (n = 20) or placebo (n = 16) once per day for 8 weeks. Weight and waist circumference were assessed weekly. The primary endpoint was the change from baseline in body weight for the herbal blend group compared with placebo. Secondary assessments included waist circumference, appetite, craving, bowel health, and safety and tolerability. Results: After 8 weeks, the herbal blend group lost an average of 3.7 kg (95% CI of 3.0 to 4.5 kg); whereas the placebo group lost 0.1 kg (95% CI of -0.7 to 1.0 kg). This difference in mean weight loss between the herbal blend and placebo groups was statistically significant (P <.001). A statistically significant reduction in waist circumference was also observed for the herbal blend compared with placebo (P <.001). The herbal blend was well tolerated; no adverse events were reported. Conclusion: Daily administration of this blend of herbal extracts, administered once daily, may produce weight loss.
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We are still doing research on 30 kind of ephemeral and perennialgramineous, bosk and wooded in our country. Nation`s enterprise in industries importing essential oils from abroad and they are using in product of medicine, food and beauty. Whole world`s most of them still researching and using widely Mentha L (Horsemint) plant in crop production and if we naturalize this Mentha L it will show result good result in plant raw material of nature and important to our economy as well.Key words: Mentha longifolia; Menth arvensis, Biological characterIntroductionEach year resource availability of raw material is proved to be not enough and it shows in research of resource in medical plant range and also what plant shows low resourceof raw material has to provide before the plant germinate or during fl owering stage in every year. Nowadays this plant is destroying and possibility of grow again is decreasing, because of the people who has interest in profi t they are taking away a lot of rhizome roots. The result of 100 scrip in Mongolian medicine shows that we supplied 43.75% of raw material in plants are from our fl ora and 56.25% is from other country. So it shows bad affect to our economy that still using other country`s resource and getting import from them. Then we have naturalize the plants in our weather conditions and try to detect innovative biological active ingredients and do research that has explained by modern science. Mongolian medicine need phytogenic of rareplants from other foreign country, so that`s why we are still doing research on how to naturalize plants in our country.Goal: How to plant Metha L. (Horsemint) in fi eld area that in order to determine the nature this plant and next try to know purpose under the following main objectives. There are:1. To recognize the naturalizing plant division2. To identify the qualifi cation of naturalizing plant division and do research ratio with anatomical result3. Get recognition of the importance in Metha L. (Horsemint)Materials and methodsThings that involved in research (blossom) take middle leaf and in order to prepare slice for anatomy research, cut the middle of leaf, get in foam plastic sponge and cut it, blue, paint it with sapphire, put it on the glass shelf make jelly and in order to prepare slice done with 8-10 frequency. According to traditional method with the help of “Enaval” microscope research leaf’s inside anatomy and textural fi nished (Гзырян,1981; Эзау 1980; В.К.Василевская,А.А.Бутник, 1981; Гамалей, 1984). The plants leaf that involved in research anatomy picturedwith the help of “PA-4”that camera.
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OBJECTIVE@#To determine the potential antibacterial activity of ethyl acetate and aqueous extracts from Mentha longifolia L. (M. longifolia) and hydroalcoholic extract of Zataria multiflora Boiss. (Z. multiflora) against important human pathogens.@*METHODS@#Pseudomonas aeruginosa, Shigella dysenteriae, Klebsiella pneumoniae (K. pneumonia), Enterobacter cloacae, Salmonella typhi, Proteus mirabilis, Serratia marcescens, Bacillus cereus, Staphylococcus saprophyticus and Staphylococcus aureus were kinds of pathogenic bacteria to determine the antibacterial effect of aqueous and ethyl acetate extracts of M. longifolia and hydroalcoholic extract of Z. multiflora using broth microdiluation method.@*RESULTS@#The lowest minimum inhibitory concentration and minimum bactericidal concentration values for K. pneumonia and Pseudomonas aeruginosa (1.25 and 2.5 mg/mL) were observed by the hydroalcoholic extract of Z. multiflora and the lowest minimum inhibitory concentration and minimum bactericidal concentration values for K. pneumonia and Serratia marcescens (2.5 and 5 mg/mL) were observed by the aqueous extracts of M. longifolia.@*CONCLUSIONS@#In conclusion, it seems that Z. multiflora and M. longifolia extracts could inhibit the growth of all of the mentioned bacteria.
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Objective: To determine the potential antibacterial activity of ethyl acetate and aqueous extracts from Mentha longifolia L. (M. longifolia) and hydroalcoholic extract of Zataria multiflora Boiss. (Z. multiflora) against important human pathogens. Methods: Pseudomonas aeruginosa, Shigella dysenteriae, Klebsiella pneumoniae (K. pneumonia). Enterobacter cloacae, Salmonella typhi, Proteus mirabilis, Serratia marcescens, Bacillus cereus, Staphylococcus saprophyticus and Staphylococcus aureus were kinds of pathogenic bacteria to determine the antibacterial effect of aqueous and ethyl acetate extracts of M. longifolia and hydroalcoholic extract of Z. multiflora using broth microdiluation method. Results: The lowest minimum inhibitory concentration and minimum bactericidal concentration values for K. pneumonia and Pseudomonas aeruginosa (1.25 and 2.5 mg/mL) were observed by the hydroalcoholic extract of Z. multiflora and the lowest minimum inhibitory concentration and minimum bactericidal concentration values for K. pneumonia and Serratia marcescens (2.5 and 5 mg/mL) were observed by the aqueous extracts of M. longifolia. Conclusions: In conclusion, it seems that Z. multiflora and M. longifolia extracts could inhibit the growth of all of the mentioned bacteria.