ABSTRACT
Mesentenc lipodystrophy is part of a spectrum of idiopathic primary inflammatory and fibrotic processes that affect the mesentery. Pathophysiologically, these processes may affect the integrity of the gastrointestinal lumen and mesenteric vessels by a mass effect. We report a 64 year old male with an ulcerative colitis who consulted in the emergency room due to hematochezia. The computed tomography revealed a marked mesenteric thickening and colon and rectal wall lesions. The patient was subjected to a proctocolectomy with a good postoperative evolution.
La lipodistrofía mesentérica es una enfermedad inflamatoria crónica inespecífica progresiva que afecta el tejido adiposo del intestino delgado (mesenterio) o del mesocolon. Su etiología es idiopática y su fisiopatología permanece incierta. La lipodistrofía mesentérica con compromiso colorrectal es una condición muy poco frecuente y su asociación a colitis ulcerosa es aún mßs rara. No hemos encontrado ningún reporte previo en la literatura. Se comunica un caso de lipodistrofía colorrectal asociada a colitis ulcerosa que se presentó con sangrado digestivo bajo agudo masivo.
Subject(s)
Humans , Male , Middle Aged , Colitis, Ulcerative/pathology , Gastrointestinal Hemorrhage/etiology , Panniculitis, Peritoneal/surgery , Panniculitis, Peritoneal/pathology , Gastrointestinal Hemorrhage/surgery , Lipodystrophy , Mesentery/pathology , Treatment OutcomeABSTRACT
Mesenteric panniculitis is an extremely rare inflammatory condition of the adipose tissue of unknown etiology. It is characterized by extensive, progressive fibrosis of the mesenteric fat tissue, leading to tumor formation. Clinical manifestations vary according to the process involving the structures. Abdominal pain accompanied by nausea, malaise, pyrexia, and weight loss and a poorly defined mass are common presentations. Major pathologic changes include (1) degeneration of mesenteric fat, (2) an inflammatory reaction, and (3) fibrosis of the adipose tissue. We present four patients with an aggressive form of mesenteric pannicultis with characteristic histopathologic features. We discuss the relationship between the histopathologic features and the surgical intervention in these cases.
Subject(s)
Humans , Abdominal Pain , Adipose Tissue , Fever , Fibrosis , Nausea , Panniculitis, Peritoneal , Weight LossABSTRACT
Mesenteric panniculitis is a rare inflammatory condition of mesenteric adipose tissue in which the mesentery is replaced with fibrosis. The frequent symptoms of mesenteric panniculitis are palpable mass, abdominal pain and gastrointestinal obstructive symptoms. In the majority of cases, its course is self-limiting and the prognosis is favorable. 3 cases of mesenteric panniculitis are described that presented with obstructive symptoms of gastrointestinal tract, which occurred in 2 weeks following colectomy of colonic tumors. And reviewed the symptomatology, pathology, treatment, and outcome of this disorder.