ABSTRACT
Leiomyosarcoma are malignant mesenchymal tumors usually found in the uterus, retroperitoneaum, gastrointestinal tract, or deep soft tissue. They do however, rarely occur as primary skin tumors. Metastases from a leimyosarcoma to skin are unusual. We report a case of metastatic leiomyosarcoma on the scalp. A 47-year -old female had hysterectomy following diagnosis of leiomyosarcoma 17 months ago. She presented with an 8 months history of a solitary nontender nodule on the scalp. The histological examination revealed a well demarcated, quite high cellular tumor nodule in the deep dermis . A tumor was usually composed of spindle cells with abundant eosinophilic cytoplasm and elongated, blunt ended nuclei. Some other cells showed pleomorphic nuclei and mitotic figures. Immunohistopathological staining of smooth muscle actin was positive. A diagnosis of metastatic leiomyosarcoma was made on histological and immunohistopathological findings.