ABSTRACT
“Mi-byo” (pre-disease) is a special concept in Chinese Medicine proposed about 2,200 years ago in the ancient text <i>Ko-tei-nai-kei</i>, which states that “a Saint-like Doctor” can cure “mi-byo”. However, no one has been saintly enough to explain an actual “mi-byo” status to date. In the 21 th century, as immunology has developed, the novel notion of “homeostatic inflammation” began to be postulated. Here, “homeostatic inflammation” means the self-repairing steps initiated by innate immune sensors when they encounter either PAMPs (pathogen-associated molecular patterns) or with DAMPs (danger signal-or damage-associated molecular patterns) composed of either lipids-or nucleic acids-related substances through their own TLRs (toll-like receptors) or NLRs (NOD-like receptors), respectively. If such “homeostatic inflammation” does correlate with the “mi-byo”, perhaps we can control it by using herbal medicines containing various saponins, essential oils, alkaroids, and flavonoids that may reinforce innate barriers by regulating the effect of lipids and nucleic acids.
ABSTRACT
"chi mi-byo (premorbidity) or zhi-weibing is defined as "preventive treatment of disease" in the "Annual Report on Health and Welfare 1997". In China, in the 2006 five-year plan for the "zhi-weibing" policy and in the 2008 "zhi-weibing" project, the policy has been changed in quality to emphasize prevention, "yo-jo or yangsheng (care of life)", and health for the purpose of improving lifestyle-related diseases and reducing the medical costs.<BR> The word "zhi-weibing" is used in "Suwen" and "Ling Shu" in reference the following: prevention, "yangsheng", and the initial/early treatment at the onset of disease. Additionally in "Nanjing" and "Jingui Yaolue", "zhi-weibing" means predicting the change of disease and preventing the progress of disease. Furthermore in Kampo Ikkando Medicine in Japan, it means improvement of constitution.<BR> In this symposium, I touched on the following: <BR>Volunteer activity reports at disaster areas<BR>Macroscopic viewpoint of current medical state (health issue in modern times)<BR>The relationship of health, disease, and the power to cure oneself<BR>"zhi-weibing or chi mi-byo"<BR>The world of Tao (way, path) and Mei (life)<BR>The "zhi-weibing" policy in China<BR>Symposiasts spoke on topics as follows: <BR> 1) Ascertaining the history of "zhi-weibing or chi mi-byo" and terminological issues like "chi mi-byo" or "mi-byo chi" in Japan<BR> 2) As a clinical practice of "chi mi-byo", an approach to a part of various methods of "yangsheng or yo-jo" based on the power to cure oneself and holistic healing method, the initial treatment, preventing the progress of disease, and the improvement of constitution<BR> 3)Achievement of the initial treatment of "Jingei-Kiko pulse diagnosis" and checking "the pulsation type and clinical condition"<BR>Whenever thinking about the future of the field of acupuncture and moxibustion, life quality of each and every human being, health, happiness, and medical economy, I would be much obliged if the contents of this "chi mi-byo" symposium are helpful to inspire medical care and the Society of Medicine, all healthcare professionals, and all patients.