Effect of low-level LASER therapy versus CAD/CAM Michigan splint on patients with Temporomandibular Muscle Disorders: a randomized clinical trial / Efeito da terapia LASER de baixa potência versus placa de Michigan CAD/CAM em pacientes com Distúrbios Temporomandibulares musculares: um ensaio clínico randomizado

Objective: This study aimed to evaluate the efficacy and sustainability of using low level LASER therapy and CAD/CAM Michigan splint on improving the range of mandibular movements, muscle activity and reducing the pain. Material and Methods: 56 female patients were randomly divided into two groups. Group A: Patients received applications of low-level LASER therapy using semiconductor InGaAsp diode LASER type 940 nm with continuous mode of operation, applied for 180 sec per session for 12 sessions. Group B: Patients received Michigan splint of 2 mm thickness constructed on their upper teeth, the splint was 3D digitally printed. Electromyography was used to evaluate muscle activity, visual analogue scale was used to evaluate the pain intensity, ARCUS digma facebow was used to evaluate range of mandibular movements, and maximum mouth opening was taken using a millimeter ruler. They were measured before the beginning of the treatment, and at three and six month follow-up periods. Results: The results revealed that both low-level LASER therapy and Michigan splint reduce the myofascial pain, improved the range of the mandibular movements, and the muscles activity, but the effect of the low-level LASER therapy was more profound and sustainable. After 6 months from the beginning of the treatment, changes in masseter muscle activity (P= 0.001; effect size= 1.757), pain intensity (P= 0.003; effect size= 3), and range of mandibular movement (P= 0.001, effect size= 1.729) differed significantly between the two groups. Conclusions: Low-level LASER therapy had a better and more sustainable effect on reducing the pain intensity and improving the muscle activity as well as the mandibular movement when compared to Michigan splint (AU)

Objetivo: Este estudo teve como objetivo avaliar a eficácia e a durabilidade do uso da terapia LASER de baixa potência e da placa de Michigan CAD/CAM na melhora da amplitude dos movimentos mandibulares, atividade muscular e redução da dor. Material e Métodos: 56 pacientes do sexo feminino foram divididos aleatoriamente em dois grupos. Grupo A: os pacientes receberam aplicações de terapia LASER de baixa potência utilizando diodo semicondutor InGaAsp LASER tipo 940 nm em modo contínuo de operação, aplicado por 180 segundos por sessão durante 12 sessões. Grupo B: os pacientes receberam a placa de Michigan com uma espessura de 2 mm confeccionada sobre a arcada superior, a placa foi impressa digitalmente em 3D. A eletromiografia foi utilizada para avaliar a atividade muscular, a escala visual analógica foi utilizada para avaliar a intensidade da dor, o arco facial ARCUS digma foi utilizado para determinar a amplitude dos movimentos mandibulares e a abertura máxima da boca foi medida com uma régua milimétrica. Todas as medidas foram realizadas antes do início do tratamento e nos períodos de acompanhamento de três e seis meses. Resultados: Os resultados revelaram que tanto a terapia LASER de baixa potência como a placa de Michigan reduziram a dor miofascial, aumentaram a amplitude dos movimentos mandibulares e melhoraram a atividade muscular, mas o efeito da terapia LASER de baixa potência foi mais profundo e duradouro. Após 6 meses do início do tratamento, as alterações na atividade do músculo masseter (P= 0. 001; tamanho do efeito= 1,757), intensidade da dor (P= 0,003; tamanho do efeito= 3), e amplitude de movimento mandibular (P= 0,001, tamanho do efeito= 1,729) diferiram significativamente entre os dois grupos. Conclusão: A terapia com LASER de baixa potência teve um efeito melhor e mais duradouro na redução da intensidade da dor e na melhora da atividade muscular, bem como do movimento mandibular, quando comparada à placa de Michigan(AU)

Study on the value of Michigan nerve screening scale, pain and tactile temperature detection and vibration perception threshold in diagnosing diabetic peripheral neuropathy / 中国医师进修杂志

Objective:To analyze the diagnostic value of Michigan nerve screening Scale (MNSI), pain, touch and temperature detection combined with vibratory perception threshold (VPT) in diabetic peripheral neuropathy (DPN).Methods:A total of 500 patients with type 2 diabetes mellitus (T2DM) who received inpatient treatment in Xinhua Hospital Chongming Branch Affiliated of Shanghai Jiao Tong University School of Medicine from January to December 2018 were selected. Sixty four patients with DPN were enrolled in the DPN group, and the remaining 436 patients were enrolled in the no-DPN group. The clinical data and the results of MNSI scale, pain, touch and temperature detection thresholds and VPT of the two groups were compared. Receiver operating characteristic (ROC) curve was drawn to analyze the clinical value of single and combined examination indicators in the diagnosis of DPN.Results:MNSI symptom questionnaire score and MNSI physical examination score in DPN group were higher than those in no-DPN group: (3.00 ± 1.35) scores vs. (1.69 ± 0.52) scores, (1.57 ± 0.50) scores vs. (1.01 ± 0.24) scores; the proportion of touch regression, pain regression and temperature regression was significantly higher than that in no-DPN group; and the levels of VPT in the DPN group was higher than that in the no-DPN group: (26.34 ± 5.03) V vs. (17.97 ± 6.82) V, there were statistical differences ( P<0.01). When the single index was diagnosed, the area under the curve (AUC) value of VPT was the highest (0.825), and significantly higher than the pain, touch and temperature detection ( P<0.01). The AUC value of VPT + MNSI in combined diagnosis was the highest (0.738), and the sensitivity and specificity of DPN diagnosis were 51.56% and 96.10%, respectively. Conclusions:Compared with MNSI scale score, sensory detection such as pain, touch and temperature, VPT has the best diagnostic efficiency for DPN, while combined with MNSI, the specificity can be further improved, but the sensitivity decreases, which is worthy of clinical attention.

Prevalence and burden of neuropathy among patients in the Eastern Visayas Regional Medical Center Family Medicine Diabetes Wellness Clinic

Introduction@#Diabetes Mellitus is a chronic non-communicable disease that has been increasing in prevalence worldwide. Preventing and treating diabetes and its complications have been a burden in the health care system. Diabetic neuropathy is its frequent complication and in the long run, is associated with a negative impact on the functioning and quality of life. Hence, its early detection can prevent and delay its sequelae and improve patients’ quality of life.@*Objective@#To determine the prevalence and burden of neuropathy among diabetic patients of Eastern Visayas Regional Medical Center (EVRMC) Family Medicine Diabetes Wellness Clinic@*Methods@#This was an analytical cross-sectional study. Patients at the EVRMC Family Medicine Diabetes Wellness Clinic from May to October 2020 were included. The Michigan Neuropathy Screening Instrument was used to diagnose diabetic neuropathy. Descriptive statistics, Chi-square test, and Fisher’s exact test were used to determine the association between socio-demographic profile and clinical characteristics among neuropathic patients.@*Results@#Two hundred ten patients were enrolled. Majority were female (66.7%), ≥60 years old (58.1%), with vocational/college degrees (37.1%), unemployed (75.2%), did not have glycemic control (80%), had diabetes for ≤5 years (57.1%), and took two maintenance medications (46.7%). Biguanide was the most common maintenance drug (70.5%). Among diabetic patients, 30.5% had neuropathy. Statistically significant associations were seen in ≥60 years old [OR 1.92, p=0.04], with vocational/ college degrees [OR 2.17, p=0.01], and with diabetes for 6-10 years [OR 2.42, p=0.01] and ≥20 years [OR 5.07, p=0.01.@*Conclusion@#Diabetes Mellitus was prevalent in elderly age group, female gender, with vocational/college degrees, and unemployed. Most had uncontrolled sugar, had diabetes for ≤5 years, and took two maintenance drugs. Only 30.5% had neuropathy. Diabetic patients ≥60 years old, had vocational/college degrees, and had longer duration of the disease had higher odds of having diabetic neuropathy.

Assessing efficacy of diabetes school using diabetes knowledge scale in Turkey

Background: Diabetes education, as an essential component of diabetes management, improves various aspects of diabetes mellitus including lowering Haemoglobin A1c. There is a number of surveys evaluating diabetes knowledge.Methods: The purpose of this study to measure diabetes knowledge of patients with diabetes mellitus after a structured group education programme named as diabetes school. This study is an observational study and the design is a cohort study. The study took place in 2017-2018. The duration of follow-up is 4 weeks. Fifty-four patients aged over 18 with a previous diagnosis of diabetes mellitus, who attended to the diabetes school education programme, were included to the study. Twenty-three patients participated in the true-false version of the revised Michigan diabetes knowledge questionnaire before and after the programme.Results: Twenty female and 3 male patients were aged 60.43±9.97 years. The scores improved significantly after the education programme (7.61±4.59 vs 12.39±3.35, p<0.0001). The number of patients correctly identifying more than half of the statements showed a steep increase after the programme (n=6, 26.0% vs n=17, 73.9%). Before education programme 13 had poor knowledge, 9 had moderate, and 1 had good knowledge. After completion 6 had poor knowledge, 11 had moderate, and 5 had good knowledge.Conclusions: Diabetes school is effective in improving diabetes knowledge in patients with diabetes mellitus. Revised Michigan Diabetes Knowledge Questionnaire can be used to evaluated diabetes knowledge. It may aid to detect the subgroup of patients who are lack knowledge of various aspects of diabetes mellitus.

Prevalence of peripheral neuropathy among diabetic patients in a tertiary care hospital

Introduction: The burden of diabetes mellitus (DM) is on the rise especially in developing countries like India. Due to its chronic nature DM tends to cause many debilitating complications and diabetic peripheral neuropathy (DPN) is one of them. The aim of this study is to determine the prevalence of DPN among patients attending a tertiary care hospital and to identify the determinants associated with it. Materials and methods: A cross-sectional study was conducted in diabetic patients attending a tertiary care hospital in Kancheepuram district of Tamil Nadu from May 2018 till September 2018. A total of 203 diabetic patients were asked to respond to the patient history version of Michigan neuropathy screening Instrument and examinations were conducted after obtaining consent from them. The data were analyzed in terms of descriptive statistics as well as bivariate analysis. Results: The prevalence of DPN using the MNSI history version and MNSI examination were found to be 31% and 24% respectively. The major determinants were found to be age more than 50 years (OR: 0.24, CI: 0.123- 0.467), P<0.00001, HbA1C > 6.5 (OR: 0.467, CI: 1.90 – 0.356, P= 0.05). Conclusions: This study showed that the prevalence of peripheral neuropathy among diabetic patients was 41.5% and the major determinants were age more than 50 years and poor HbA1C control. Early detection through routine screening and regular follow up examinations will reduce the burden of disability among diabetics and improve their quality of life significantly

Effects of combination therapy of calcium dobesilate dispersible and monosialotetrahex-osylganlioside sodium on serum inflammatory cytokines IL-6 and MCP-1 in elderly patients with painful diabetic peripheral neuropathy / 中国基层医药

Objective To observe the efficacy of combination therapy of calcium dobesilate dispersible and monosialotetrahexosylganlioside sodium on interleukin-6 (IL-6) and monocyte chemotactic protein-1 (MCP-1) in elderly patients with painful diabetic peripheral neuropathy.Methods From January 2012 to May 2017,in the Second People's Hospital of Lianyungang 70 patients of painful diabetic peripheral neuropathy,aged ≥60 years,were analyzed in this study.They were randomly divided into observation group (35 cases) and control group (35 cases).The observation group was treated with 40mg monosialotetrahexosylganlioside sodium dissolved in 250mL physiological saline,intravenous infusion per day,and oral calcium dobesilate dispersible 0.5g twice a day for two weeks.The control group was treated with methylcobalamin injection 0.5mg per day for two weeks.The clinical treatment effects and levels of IL-6 and MCP-1 were observed and compared between the two groups.Results After two weeks of treatment,the MDNS and MNSI scores of the observation group [(13.09 ± 5.38)points,(2.53 ± 1.19)points] were significantly lower than those of the control group [(18.31 ± 6.13) points,(4.19 ± 1.05) points,t =2.036,2.365,all P ＜ 0.05] and those before treatment [(21.26 ± 4.28) points,(5.40 ± 0.89) points,t =3.251,3.698,all P ＜ 0.05].The VAS-PI scores in the observation group [(6.24 ± 1.25) points,(4.13 ± 1.69) points] were significantly lower than those in the control group[(7.26 ± 1.28) points,(6.34 ± 2.65) points] at the first and second week (t =3.265,5.395,all P ＜ 0.05).The serum levels of inflammatory cytokines IL-6 and MCP-1 in the observation group [(15.16 ±0.88) ng/L,(157.19 ± 11.22) ng,/L] were significantly lower than those in the control group[(17.87 ± 1.19) ng/L,(198.21 ± 12.07)ng/L,t =2.152,1.365,all P ＜0.05]and those before treatment[(20.26 ± 1.05) ng/L,(260.44 ± 13.63) ng,/L,t =1.235,0.965,all P ＜ 0.05].Conclusion Combination of calcium dobesilate and mono-sialotetrahexosyl ganglioside may alleviate the sensory and pain sensations in patients with painful diabetic peripheral neuropathy,possibly by reducing the level of inflammatory cytokines IL-6 and MCP-1.

Moms' Empowerment Program participation associated with improved physical health among Latinas experiencing intimate partner violence / La participación en la iniciativa Programa de Empoderamiento de las Mamás, se asocia con mejoría de la salud física de las mujeres latinas objeto de violencia de pareja / Participação no Programa de Empoderamento de Mães associada à melhora da saúde física em mulheres latinas que sofrem violência infligida pelo parceiro íntimo

ABSTRACT Objective To evaluate whether participation in the Moms' Empowerment Program (MEP), a 10-week, 10-session intervention designed to provide support and increase access to available community resources for women experiencing intimate partner violence (IPV), enhanced the physical health of participants who self-identified as Latina. Methods Mothers of children ages 4-12 who self-identified as Latina and had experienced IPV within the past two years were recruited at three intervention sites in Michigan, Ohio, and Texas, via community postings and referrals from agencies serving IPV-exposed families. Selected study participants (n = 93) were assigned to one of two groups: Treatment (immediate enrollment in the MEP) or Control (placement on a waitlist with an invitation to participate in the MEP after the 10-week study period). Data were drawn from two structured interviews, one at the time of recruitment for the study (Time One), and one following the intervention or wait period (Time Two). Results After controlling for age, educational attainment, and partner residence (living with a violent partner at the time of the interview), multilevel modeling revealed that improvement in physical health over time was significantly greater among women who participated in the intervention relative to controls. Conclusions These data suggest that enhancing interpersonal connectedness and access to resources positively affects physical health for Latinas experiencing IPV.

RESUMEN Objetivo Evaluar si la participación en la iniciativa Programa de Empoderamiento de las Mamás (PEM), una intervención de 10 sesiones en 10 semanas concebida para prestar apoyo a mujeres autodefinidas como latinas objeto de violencia de pareja y brindarles un mayor acceso a los recursos comunitarios, mejoró la salud física de las participantes. Métodos Participaron en el estudio madres de niños de 4 a 12 años de edad que se autodefinieron como latinas y habían sido objeto de violencia de pareja en los últimos dos años. El reclutamiento de las participantes se hizo en tres sitios donde se realizaba la intervención, en Michigan, Ohio y Texas, por medio de avisos comunitarios y referencias de organismos que atienden a familias expuestas a la violencia de pareja. Las participantes seleccionadas para el estudio (n = 93) se asignaron a uno de los dos grupos siguientes: grupo de tratamiento (se inscribieron de inmediato en el PEM) o grupo de control (se pusieron en una lista de espera y se invitaron a participar en el PEM una vez que transcurrieran las 10 semanas del estudio). Se extrajeron datos de dos entrevistas estructuradas, una realizada al inscribir a las participantes en el estudio (fecha 1) y otra después de la intervención o el período de espera (fecha 2). Resultados Después de controlar la edad, el nivel de escolaridad y el lugar de residencia de la pareja (vivir con una pareja violenta en el momento de la entrevista), el modelo de varios niveles mostró que el mejoramiento de la salud física con el transcurso del tiempo era significativamente mayor en las mujeres que habían participado en la intervención que en las mujeres del grupo de control. Conclusiones Estos datos indican que mejorar la conexión interpersonal y el acceso a los recursos tiene un efecto positivo en la salud física de las mujeres latinas que son objeto de violencia de pareja.

RESUMO Objetivo Avaliar se a participação no Programa de Empoderamento de Mães (PEM), uma intervenção composta por 10 sessões semanais com o objetivo de prestar apoio e melhorar o acesso aos recursos disponíveis na comunidade para mulheres que sofrem violência infligida pelo parceiro íntimo, promove a melhora da saúde física das participantes que se reconhecem como latinas. Métodos Mães de crianças com idade de 4 a 12 anos que se reconhecem como latinas e sofreram violência infligida pelo parceiro íntimo nos dois anos anteriores foram recrutadas em três centros de intervenção em Michigan, Ohio e Texas, por meio de anúncios na comunidade e o encaminhamento de órgãos que fazem o atendimento de famílias expostas à violência infligida pelo parceiro íntimo. As participantes selecionadas para o estudo (n = 93) foram divididas em dois grupos: grupo de tratamento (inscrição imediata no PEM) ou grupo de controle (inscrição na lista de espera com convite para participar do PEM após o período do estudo de 10 semanas). Os dados foram coletados em duas entrevistas estruturadas, uma ao recrutamento para o estudo (momento 1) e a outra após a intervenção ou o período de espera (momento 2). Resultados Após controlar idade, nível de instrução e residência do parceiro (coabitação com o parceiro violento no momento da entrevista), a análise com o modelo de múltiplos níveis demonstrou que houve uma melhora significativamente maior da saúde física ao longo do tempo nas participantes da intervenção em comparação ao grupo de controle. Conclusões Esses resultados indicam que reforçar o senso de conexão interpessoal e melhorar o acesso aos recursos têm um impacto positivo na saúde física de mulheres latinas que sofrem violência infligida pelo parceiro íntimo.

Clinical Study on Electronic Moxibustion in Treating Diabetic Peripheral Neuropathy / 上海针灸杂志

Objective To observe the clinical efficacy of electronic moxibustion in treating diabetic peripheral neuropathy due to liver-kidney deficiency. Method Ninety patients with diabetic peripheral neuropathy due to liver-kidney deficiency were randomized into a treatment group of 44 cases and a control group of 46 cases. The treatment group was intervened by acupoint therapy by warm electronic moxibustion, while the control group was intervened by foot bath with Chinese medication. For both groups, 10 treatment sessions were taken as a course of treatment, for 3 courses in total. Before and after the treatment, the whole blood viscosity, blood lipids, fasting blood glucose (FBG), glycosylated hemoglobin (GHb) and Michigan Neuropathy Screening Instrument (MNSI) were evaluated in the two groups. Result The whole blood viscosity indexes, blood lipids levels, FBG level and GHb level didn't show significant differences after the treatment in the two groups (P>0.05). The intra-group and inter-group comparisons of MNSI score showed significant differences after the treatment (P<0.01); there was a between-group difference in the change of MNSI score after the treatment (P<0.01). Conclusion Electronic moxibustion is an effective approach in treating diabetic peripheral neuropathy.

Observations on the Therapeutic Effect of Electronic Moxibustion on Diabetic Peripheral Neuropathy / 上海针灸杂志

Objective To investigate the clinical efficacy of electronic moxibustion in treating diabetic peripheral neuropathy (liver-kidney deficiency type).Methods Ninety patients with diabetic peripheral neuropathy (liver-kidney deficiency type) were randomized to a treatment group (44 cases) and a control group (46 cases).The treatment group received electronic moxibustion and the control group,Chinese herbal fumigation of feet.Both groups were treated 10 times as a course for a total of three courses.The TCM symptom total score and the Michigan Neuropathy Screening Instrument (MNSI) score were recorded in the two groups before and after treatment.The clinical therapeutic effects were compared between the two groups.Results There was a statistically significant pre-/post-treatment difference in the TCM symptom total score in both groups after one,two and three courses of treatment (P＜0.01).The TCM symptom total score improvement rate was (60.9±16.7)％ in the treatment group and (56.6±19.2)％ in the control group;there was a statistically significant difference between the two groups (P＜0.01).The total efficacy rate was 97.7％ in the treatment group and 95.7％ in the control group;there was no statistically significant difference between the two groups (P＞0.05).The pre-/post-treatment MNSI score difference value was (2.98±3.66) in the treatment group and (0.78±2.92) in the control group;there was a statistically significant difference between the two groups (P＜0.01).Conclusions Electronic moxibustion is an effective way to treat diabetic peripheral neuropathy.Its therapeutic effect is slightly better than that of Chinese herbal fumigation.

Effects of ginsenoside Rg3 on vasculogenic mimicry of breast cancer MCF-7 cell line / 天津医药

Objective To investigate the inhibitory effects and mechanism of ginsenoside Rg3 on vasculogenic mimicry of human breast cancer MCF-7 cell line. Methods The MCF-7 cells at logarithmic growth phase were obtained, and were cultured with different concentrations (0, 20, 50, 100, 150 and 300 mg/L) of ginsenoside Rg3. Cells cultured without Rg3 were served as controls. The IC50 were determined by CCK8 assay and anti-angiogenic effects were performed for testing the potential of tube-like structure (TLSs) formation. The expression levels of VEGF-A, MMP 9 and HIF-1αwere detected by Western blotting and real-time PCR. The secreted contents of VEGF-A and MMP9 were detected by enzyme linked immunosorbent assay (ELISA). Results The ginsenoside Rg3 suppressed the proliferation of MCF-7 cells in a dose-dependent manner, in which IC50 was (115.34±8.50) mg/L. The formation numbers of TLSs in MCF-7 cells were significantly inhibited by Rg3 in concentration dependent manner in 50 mg/L, 100 mg/L and 150 mg/L for (19.0 ± 1.0), (15.0 ± 1.5), and (10.0±1.7) vs. controls (22.0±1.8, F=150.805, P regulation of VEGF-A, MMP9 and HIF-1α.

Correlation between ultrasonic feature of tibial nerve with Michigan neuropathy screening instrument scoring system in type 2 diabetic mellitus / 天津医药

Objective To examine the correlation between the ultrasonic feature of tibial nerve and the scores of Michi?gan neuropathy screening instrument(MNSI)in type 2 diabetic mellitus (T2DM) and to provide information for early diagno?sis of diabetic peripheral neuropathy(DPN). Methods Based on scores of MNSI, 95 cases of T2DM patients were divided into three different groups:group B(0-2.4 scores), C(2.5-4.4 scores)and D(≥4.5 scores). Ultrasound parameters of group A (n=30) were compared with group B (n=32), group C (n=31) and group D (n=32). These parameters includes nerves′s an?teroposterior dimension, transverse diameter, cross-sectional area and fasciculus echo, thescreen clothstructure, epineuri?um and the demarcation with neighbourhood structures. Correlation of MNSI with ultrasound performance of tibia nerve was also tested. Results Compared with group A, transverse diameter in group B did not show a obvious change, but anteropos?teror dimension, transverse diameter, cross-sectional area in group C, group D all increase.(P 0.05). There was a positive correlation between the nerves′s anteroposterior di?mension, transverse diameter, cross-sectional area with MNSI, rs were 0.656、0.657 and 0.681 respectively (P<0.05 in all three cases). Conclusion Certain correlation was observed between MNSI and tibial never ultrasonic feature in T2DM pa?tients;the higher MNSI scores , the greater chance of presence of abnormal sonographic features of tibial nerve.

El arco facial en la elaboración de las férulas oclusales tipo Míchigan / Face bows in the production of Michigan occlusal splints

Introducción: la férula oclusal tipo Míchigan (FOM) es un dispositivo usado frecuentemente para el manejo de pacientes con bruxismo. La literatura menciona el uso del arco facial para el montaje de modelos en el articulador semiajustable, sin embargo el beneficio de este en la elaboración de las FOM aún es controvertido. Por lo tanto el objetivo de esta investigación fue comparar el registro de número de puntos de contacto y el tiempo de ajuste entre las FOM elaboradas con y sin el uso del arco facial en pacientes con diagnóstico de bruxismo. Métodos: se elaboraron 90 férulas entregadas a 45 pacientes de la Clínica de Rehabilitación Benemérita Universidad Autónoma de Puebla (BUAP), previo diagnóstico de bruxismo. Las dos férulas elaboradas (una con modelos montados con arco facial y otra sin él), se compararon en el articulador y clínicamente. Se registró el número de puntos de contacto obtenidos en ambas férulas y el tiempo de ajuste requerido. Las comparaciones se hicieron con la prueba estadística de Wilcoxon y significancia menor a 0,05. Resultados: la media de puntos de contacto en boca de las férulas con el uso del arco fue superior (11,67) a la de sin uso del arco (11,58) sin diferencias significativas (p = 0,799). El tiempo de ajuste fue superior en las férulas elaboradas sin arco (51 s) que con arco (33 s), sin diferencias significativas (p = 0,332). Conclusión: no existen diferencias significativas con el uso del arco facial o sin él para la elaboración de las FOM en pacientes bruxómanos.

Introduction: Michigan occlusal splints (MOS) are frequently used for the management of patients with bruxism. The literature mentions the use of face bows for mounting models in semi-adjustable articulators, but its benefit in the production of MOS is still controversial. Therefore, the objective of this study was to compare the record of number of contact points and mounting time between MOS made with and without face bows in patients diagnosed with bruxism. Methods: a total of 90 splints were made and distributed among 45 patients diagnosed with bruxism at the Oral Rehabilitation Clinic of Benemérita Universidad Autónoma de Puebla (BUAP). The two splints (one made with a face bow mounted model and the other one without it) were compared at the articulator and clinically. The number of obtained contact points was recorded in both splints as well as the time needed for mounting. The comparisons were made with Wilcoxon statistical test and a significance level lower than 0.05. Results: the splints with face bows showed a greater average of contact points in the mouth (11.67) compared with the ones without face bows (11.58), with no significant difference (p = 0.799). Mounting time was higher in the splints made without face bows (51 s) compared with the ones with face bows (33 s), with no significant difference (p = 0.332). Conclusion: there are no significant differences in using face bows for developing MOS in bruxism patients.

Prevalencia de neuropatía periférica en diabéticos tipo 2 en el primer nivel de atención / Prevalence of peripheral neuropathy among primary care type 2 diabetic patients

Background: Neuropathy is a common complication of diabetic patients. Aim: To determine the prevalence of diabetic peripheral neuropathy in Type 2 diabetic patients attended at a family medicine unit. Material and Methods: Cross-sectional assessment of 348 type 2 diabetic patients aged 34-89 years (60% females) with a disease duration of 5 to 15 years. Peripheral neurological status was evaluated using The Michigan Neuropathy Screening Instrument, a tool that includes a self-assessment of symptoms and a physical examination. Results: Diabetic neuropathy was found in 240patients (69%). The prevalence in males and females was 72 and 67% respectively. The prevalence in patients with a disease duration of 5, 10 and 15 years, was 59, 69 and 77%, respectively. Fifty percent of patients with neuropathy complained of dry skin, 2% had ulcers, 43% had an abnormal perception of vibration and 29% had an abnormal monofilament test. Conclusions: The overall prevalence of peripheral neuropathy in this group of patients was 69% and was directly associated with the duration of the disease.

Validación del "Michigan Hand Outcomes Questionnaire" para población colombiana / No presenta

Propósito: validar el "Michigan Hand Outcomes Questionnaire" para el uso en población clínica colombiana, obtener una versión en español que tenga equivalencia trans-lingüística y evaluar la fiabilidad, sensibilidad al cambio, validez de contenido y de constructo del instrumento traducido y adaptado al español. Métodos: estudio observacional de validación de una escala en 205 pacientes colombianos con patología de mano asistentes a las consultas de cirugía plástica, rehabilitación y reumatología en un Hospital Universitario de referencia regional. Resultados: el análisis de componentes principales mostró seis dominios. A pesar de tener el mismo número de dominios, el contenido de algunos de ellos fue diferente a las subescalas originales. Se evaluó la consistencia interna incluyendo los 37 ítems de la escala original y se obtuvo un valor de Alfa de Cronbach de 0,92. Todas las subescalas tenían buena reproducibilidad prueba-reprueba excepto dolor. Al evaluar los resultados de la escala, tres y seis meses después de su primera aplicación, se pudo observar que había diferencias estadísticamente significativas en la puntuación total y en la de cada una de las subescalas. Conclusiones: la versión en español para Colombia del “Michigan Hand Outcomes Questionnaire” tiene buena confiabilidad, validez y sensibilidad al cambio. La evaluación de consistencia interna indicó que la escala podría ser acortada y posiblemente mejoren aún más sus propiedades psicométricas.

Purpose: to validate the Michigan Hand Outcomes Questionnaire for its use in Colombian clinical population: to translate and adapt the scale in order to obtain a cross-linguistically equivalent version in Spanish, and to assess the reliability, sensitivity to change, and content and construct validity of the Colombian Spanish version. Methods: observational study to validate a scale in 205 Colombian patients of plastic surgery, rehabilitation, and rheumatology in a University Hospital, who had a hand disorder. Results: the principal component analysis showed six domains, as in the original questionnaire, but the content of some of them differed from the original MHQ scales. We assessed internal consistency of the entire 37-item original scale, and Cronbach’s alpha was of 0,92. All scales had good test-retest reproducibility, except for the Pain scale. Upon evaluation of the results of the scale three and six months after its first application, significant differences could be observed in the total score as well as in the scores for each of the scales. Conclusions: the Colombian Spanish version of Michigan Hand Outcomes Questionnaire has good reliability, validity, and sensitivity to change. Assessment of internal consistency indicated that the scale could be reduced and its psychometric properties would possibly improve.

The Validity of Michigan Neuropathy Screening Instrument as a Screening Test and Risk Factors for Diabetic Peripheral Neuropathy

BACKGROUND: Diabetic neuropathy is a common complication of diabetes. Since neuropathy leads to ulceration and amputation, efforts to detect early and to elucidate its risk factors are ongoing. The goal of this study was to check the validity of Michigan neuropathy screening instrument (MNSI) as a screening test and its risk factors for diabetic neuropathy. METHODS: A total of 75 subjects with type II diabetes mellitus, who visited a university hospital, were investigated. We measured their duration of diabetes, height, weight, systolic blood pressure, diastolic blood pressure, fasting glucose, glycosylated hemoglobin, triglyceride, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, total cholesterol, serum creatinine, and 24-h urine albumin. MNSI tested and electrophysiological test were performed. RESULTS: The sensitivity, specificity, positive predictive value, and negative predictive value of MNSI was 63.5%, 78.3%, 86.8%, and 48.6%, respectively. Statistically significant relationships were found between neuropathy and the duration of diabetes and total cholesterol. CONCLUSION: MNSI seemed to be an appropriate screening test for diabetic neuropathy. More attention must be paid to the duration of diabetes and the total cholesterol of type 2 diabetic patients with peripheral neuropathy.

Alcoholism Prevalence and Some Related Factors in Edirne, Turkey

The aim of this research was to estimate the community prevalence of alcoholism and the potential risk factors that affect it in the Edirne provincial centre by using a scanning test. A cross-sectional study was carried out in the Edirne provincial centre. A sample population composed of 500 women and 200 men was selected randomly after the categorisation of the population according to ethnicity, age and sex. Through face-to-face interviews, data collection sheets, which were prepared to analyse potential factors affecting alcoholism frequency, were filled in by the sample population. The Michigan Alcoholism Scanning Test (MAST) was employed. According to MAST's normal grading, individuals with 5 or more points are evaluated as alcoholics. Accordingly, 8.2% of the sample population fit the definition of alcoholic. Alcoholism frequency was considerably higher in gypsies, the self-employed, smokers, and people with higher income. From logistic regression analysis alcoholism frequency was 12.4 times higher in men than in women, 3.2 times higher in gypsies than in others, 1.9 times higher in people who earned an income in the preceding week than in the unemployed, and 3.7 times higher in individuals who had smoked more than 100 cigarettes during their life or those who had smoked at least 1 cigarette for 3 months or for a longer period than in those who hadn't smoked any cigarettes. The prevalence of alcoholism in the Edirne provincial centre was similar to that in other countries in Europe. The most important finding was that alcohol consumption decreased in the unemployed, a finding that differs from that in other parts of the world. Gypsies, who differ in tradition, way of life, and job compared to the other strata of society, also suffered from higher alcohol consumption. This group usually consumed wine and generally did not eat while drinking.