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BACKGROUND@#Anatomical segmentectomy is more and more widely used in lung nodules and early stage lung cancer. Postoperative lung air leakage is one of the common complications after surgery. This study aimed to explore the effect of the application of repair materials in precise segmentectomy under thoracoscopy in reducing postoperative lung air leakage.@*METHODS@#This study included patients admitted to the Department of Thoracic Surgery of Jiangsu Provincial People's Hospital who were scheduled to undergo thoracoscopic segmentectomy from August 1, 2018 to July 31, 2019. According to the difference of the materials used in the treatment of the inter-segment interface during the operation: patients who used microporous polysaccharide hemostatic powder+fibrin adhesive glue+absorbable polyglycolic acid patch were divided into group A, and the patients with fibrin adhesive+absorbable polyglycolic acid patch were divided into group B. The preoperative basic information of all patients and the daily postoperative chest drainage volume, the indwelling time of the chest drainage tube, the chest radiograph before the chest drainage tube is removed, the chest radiograph after the chest drainage tube is removed, blood routine and postoperative hospital stay were collected and recorded, and the effect of the application of intraoperative repair materials on postoperative lung air leakage was analyzed.@*RESULTS@#There were statistically significant differences in the indwelling time of thoracic drainage tube (P=0.019) and postoperative hospital stay (P=0.017) between the two groups.@*CONCLUSIONS@#Compared with the use of the fibrin glue+absorbability polyglycolic acid patch, the use of microporous polysaccharide hemostatic powder+fibrin glue+absorbability polyglycolic acid patch in the treatment of the inter-segment interface during segmentectomy can better reduce the incidence of postoperative air leakage and shorten the postoperative hospital stay.
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Objective To evaluate the safety and efficiency of composite microporous polysaccharide pow-der in non-varicose veins of gastrointestinal bleeding treatment. Methods We retrospectively analyzed 35 cases of the past 2 years in this hospital. Those patients were clinical diagnosed with non-varicose veins of gastrointestinal bleeding and received composite microporous polysaccharide powder in hemostasis. Results All 35 patients stopped bleeding after treatment with combined treatment of composite microporous polysaccharide powder spray. All vital signs were smooth and steady such as oxyhemoglobin saturation and heart rate,without complications like irritability,deterioration of inflammation and delayed hemorrhage. Conclusion The combined utilization of com-posite microporous polysaccharide powder provided rapid and effective hemostasis in therapy of non-varicose veins of gastrointestinal bleeding,which is an effective,simple and safe operation and to be worth of being generalized.
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Objective Microporous polysaccharide hemostatic powder ( MPPHP) is a most commonly used hemostatic mate-rial, but reports are rarely seen on its application in posterior spinal orthopedic surgery.The present paper aimed to investigate the val-ue of MPPHP in stopping bleeding in posterior spinal surgery. Methods Twenty-four 5-month-old New Zealand rabbits were equally randomized to an experimental and a control group.An 8 cm-long wound was made in the back muscle of animals to establish the model of spinal posterior surgery.MPPHP was applied to the wound of the experimental rabbits but none to that of the controls.Comparisons were made between the two groups of animals in the bleeding time, in vitro coagulation time, intra-operative blood loss, and results of pre-and post-operative blood routine and histopathological examinations. Results Statistically significant differences were observed between the experimental and control groups in the mean bleeding time ([15.36 ±1.42]s vs [347.58 ±32.43]s, P0.05).Pathological examination revealed mild bleeding and a small number of red blood cells in the muscle interstitium and blood vessel lumen of the experimental rabbits as compared with the controls. Conclusion Intraoperative topical ap-plication of MPPHP can reduce blood loss and achieve rapid and efficient hemostasis in posterior spinal surgery without affecting wound healing.
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Objective:To evaluate the efficacy and safety of microporous polysaccharide hemispheres(MPH)in control of homostasis on residual liver after hepatectomy. Methods: 60 patients undergoing hepatectomy were randomized to four groups standard group,test group Ⅰ,test group Ⅱ,and control group. Patients in standard group(15 patients)were treated with routine surgical technique to achieve homostasis.In test group Ⅰ(15 patients)the MPH combined with absorbable haemostat were used as hemostatic agents while only the MPH was used in test group Ⅱ(15 patients). The other 15 patients were given absorbable haemostat as control group. The hemostasia time, the amount of blood transfusion during operation and three days after operations were evaluated, the other factors (ALT, Alb, biliary, PT)were also evaluated. Results: In the standard group, hemostasia time was (2.98?1.05) min; the blood transfusion amount was (400?200) ml during operations and (400?200) ml three days after operations; the amount of drainage was (350?100) ml. In the test group Ⅰ, hemostasia time was (3.10?0.85) min; the blood transfusion amount was (200?0) ml during operations and (200?100) ml three days after operations; the amount of drainage was (200?100) ml. In the test group Ⅱ, hemostasia time was (3.20?1.52) min; the blood transfusion amount was (200?200) ml during operations and (200?0) ml three days after operations; the amount of drainage was (150?100) ml, and while in control group, the corresponding results were (5.22?1.82) min, (600?200) ml, (400?200) ml, (400?150) ml, respectively. Satisfactory bleeding control was achieved in 5 patients with routline surgical technique, there was no significant diffterence among them. The incidence of hemostasis in control group (33%)was significantly lower than that in standard group(80%) and all test groups(73.3%, 66.7%, respectively). No hemostatic complications were noted in either group. Conclusion: MPH provides rapid, effective and safe hemostasis after hepatectomy, which can be applied in hepatectomy.