ABSTRACT
Objective:To review publications in the field of digestive endoscopic minimally-invasive resection in the past 10 years in and outside China.Methods:Literature of digestive endoscopic minimally-invasive resection in the Web of Science and CNKI databases from January 1, 2011 to July 17, 2021 was retrieved. VOSviewer 1.6.11 was used for clustering and time series analysis of countries, institutions, authors and keywords, and drawing evidence-based visualization maps, so as to analyze the cooperation among countries, academic institutions and researchers, to compare the differences in research topics between Chinese and English databases, and to predict the future research hot spots and directions.Results:A total of 22 834 English articles and 4 636 Chinese articles were included. Over the past 10 years, the number of Chinese and English publications has been growing steadily, and most of them were published in professional journals. The publications were mainly from China, Japan, South Korea and the United States, where all exceeded 2 000. The National Cancer Center of Japan had 497 publications, ranking the first among all institutions. The cooperation between academic institutions showed obvious regional characteristics, and the inter-institutional and interpersonal cooperation needed improvement. In terms of keyword clustering, there was no significant difference between Chinese and English publications, but there were two additional clusters in Chinese publications, endoscopic nursing and submucosal tumor. Overlays analysis of key words showed that endoscopic surgery, tunneling technique, and submucosal tumor could be hot spots and future directions.Conclusion:Digestive endoscopic minimally-invasive resection has experienced a vigorous development in the past 10 years with a growing number of Chinese and English publications. China is playing an increasingly important role on the international stage. The advanced nature of research focus in Chinese publications is comparable to that in English publications, yet also showing Chinese characteristics. In the future, more efforts should be taken to strengthen regional cooperation and focus on research hot spots.
ABSTRACT
Objective To compare the efficacy of ATEC system and conventional surgery for the treatment of nonpalpable breast nodules.Methods Two hundred and forty cases patients with nonpalpable breast nodules who were treated in Maternal and Child Health Hospital of Pinggu District of Beijing from September 2014 to June 2016 were admitted and randomly divided into observation group and control group,120 cases in each group.The observation group was treated with minimally invasive treatment,while the control group was treated by conventional surgery.The postoperative pathologic results,surgical parameters and complications were compared between 2 groups.Results One hundred and eighteen cases were successfully removed and 210 pathological specimens were obtained in the observation group,including 201 benign lesions in 112 cases and 9 malignant lesions in 6 cases.In the control group,208 benign lesions in 113 cases and 11 malignant lesions in 7 cases were obtained from 120 cases.There was no significant difference in the proportion or type of pathology between 2 groups(P＞0.05).The operative time,blood loss,scar length and wound healing time were all significantly lower in the observation group than those in the control group((16.72±3.65)min vs.(41.21±5.94)min,(9.45±2.35)ml vs.(28.42±7.30)ml,(3.64±0.85)mm vs.(28.51±6.34)mm,(3.36±0.67)d vs.(6.79±1.58)d;t=38.245,26.891,42.238,21.738;P＜0.001).The incidence of breast collapse or deformity in the observation group was lower than that in the control group(0 vs.6.7％,P=0.007),but there was no significant difference in the incidence of hematoma,skin ecchymosis,local infection or nodular recurrence between 2 groups(P＞0.05).Conclusion Breast minimally invasive resection is effective in the treatment of nonpalpable breast nodules,and is suitable for patients with high demands on breast appearance.