ABSTRACT
Network construction technology is the basis for network pharmacology research. Data originated from experiment, database and computational prediction can be used to construct drugome network,diseaseome network and molecular interactome net?work. The molecular network construction for the complex diseases represented by Alzheimer′s disease(AD)could be used to identify the important targets,pathogenesis and drug action mechanism,and guide drug development and drug reposition. This paper reviews techniques for molecular network construction in network pharmacology study.
ABSTRACT
Network construction technology is the basis for network pharmacology research. Data originated from experiment, database and computational prediction can be used to construct drugome network, diseaseome network and molecular interactome network. The molecular network construction for the complex diseases represented by Alzheimer′s disease (AD) could be used to identify the important targets, pathogenesis and drug action mechanism, and guide drug development and drug reposition. This paper reviews techniques for molecular network construction in network pharmacology study.