Clinical Experience of Coagulation Management in Multiple Myeloma Patient with Thrombocytopenia Using Thromboelastography: A case report / 대한마취과학회지

Multiple myeloma is malignant proliferation of plasma cells whose pathologic condition is produced by bone marrow invasion as well as excessive production of immunoglobulin. Its invasion into bone marrow causes severe pancytopenia. Therefore these patients are susceptible to thrombocytopenia and have bleeding tendency, especially during surgery. We experienced an anesthetic management of meningioma operation in a patient with multiple myeloma who showed severe thrombocytopenia and excessive abonormal immunoglobulin.

Clinical Experience of Coagulation Management in Multiple Myeloma Patient with Thrombocytopenia Using Thromboelastography: A case report / 대한마취과학회지

Multiple myeloma is malignant proliferation of plasma cells whose pathologic condition is produced by bone marrow invasion as well as excessive production of immunoglobulin. Its invasion into bone marrow causes severe pancytopenia. Therefore these patients are susceptible to thrombocytopenia and have bleeding tendency, especially during surgery. We experienced an anesthetic management of meningioma operation in a patient with multiple myeloma who showed severe thrombocytopenia and excessive abonormal immunoglobulin.

Intraoperative Coagulation Management by TEG in a Patient with Aplastic Anemia: A case report / 대한마취과학회지

This case was an acquired aplastic anemia patient who required a major operation for excision of a mediastinal mass. The authors previewed that the coagulation abnormalities would be developed due to major operation. Thus we decided to monitoring the coagulation function using the thromboelastography during the perioperative period and checked the complete blood count, concommitantly. The total blood volume lost during operation was 1800 ml, so we gave him a transfusion of 10 U's of platelet concentrate, 10 U's of pheretic platelet rich plasma and 5 U's of whole blood. The thromboelastography was a good guide that helped us to avoid excessive treatment of the coagulation abnormalities. We concluded that the thromboelastograhy was a reliable and effective monitoring system at the intraoperative coagulation management.