Pseudomyxoma peritonei: two case study and literatures review

Pseudomyxoma peritonei (PMP) is a rare neoplastic illness with unique clinical and pathologic patterns. This disease characterized by being chronic, indolent, and relapsing. It is diagnostically challenging and very vague disease. It characterized by huge amounts of thick mucinous ascites with multiple omental and peritoneal implants that is gradually fill the abdominal and pelvic cavities. The most common clinical features are progressive abdominal distention with increase in the abdominal girth. Diagnosis of Pseudomyxoma peritonei (PMP) is usually difficult due to its vague symptoms especially in the early stages. Ultrasound examination is very useful and generally has pictures similar to that of CT scan images. Treatment of Pseudomyxoma peritonei (PMP) is cytoreductive (debulking) surgery to remove the mucin and the tumor implants in the peritoneal cavity. This is followed by intraoperative hyperthermic peritoneal chemotherapy (HIPEC). Recurrence of pseudomyxoma peritonei (PMP) patients is quite common as particularly when the disease is diagnosed and treated in the late stage.

Appendiceal Intussusception Caused by the Mucocele of the Appendix

Mucocele of the appendix is basically a cystic dilatation of the appendix distal to an obstruction of the appendiceal lumen. It develops in unusual situations in which the distal lumen does not contain enough bacteria to initiate appendicitis when obstruction develops. The continuing mucous secretion causes gradual distention of the appendix and thinning of the wall until mucous secretion stops. The changes after the sudden blocking of the lumen of the appendix depend on the amount and character of the content distal to the obstruction. If the lumen is empty, the appendix distends with mucus to form a mucocele. Here we report a case which we experienced a 68-years-old female patient whose vermiform appendix had mucoceles with appendiceal intussusception.