Biometry and pathological ultrasound findings in multiple pregnancies / Características ecográficas y hallazgos patológicos en embarazos múltiples

Resumo Objectives: to determine the prevalence of pathological findings according to the type of chorionicity in pregnancies in two institutions in Bogotá, Colombia. Methods: descriptive, retrospective, cohort study. Biometric variables were calculated, and pathological findings were evaluated according to the type of chorionicity in multiple pregnancies. Statistical characterization was performed with absolute frequencies, calculation of relative frequencies in qualitative variables, standard deviation measures, median and interquartile range. In addition, a descriptive analysis of the information was carried out. Results: 528 studies were carried out in 141 pregnant women, 98.5% (n = 139) twins and 1.4% (n = 2) triplets. A prevalence of 35.4% of fetal complications was calculated. The most frequent was fetal growth restriction (p=0.37). According to each type of chorionicity, fetal growth restriction was presented in 50% (1/2) of the trichorionics, 16.6% (7/42) of the monochorionics, and 11.3% (11/97) of the dichorionics. Conclusion: fetal growth restriction was the most common finding, both in trichorionics, monochorionics and dichorionics pregnancies.

Resumen Objetivos: el objetivo del estudio fue determinar la prevalencia de los hallazgos patológicos ecográficos en embarazos múltiples de acuerdo con la corionicidad en dos instituciones en Bogotá-Colombia. Métodos: estudio de cohorte, descriptivo, retrospectivo. Las variables biométricas realizadas y los hallazgos patológicos se evaluaron de acuerdo con el tipo de embarazo gemelar. Se realizó caracterización estadística con frecuencias absolutas, cálculo de frecuencias relativas en variables cualitativas, medidas de desviación estándar, mediana y rango intercuartílico. Además, se realizó análisis descriptivo de la información. Resultados: se realizaron 528 estudios en 141 gestantes, encontrando 98,5% (n=139) gemelares y 1,4% (n=2) triples. Se calculó una prevalencia de 35,4% de complicaciones fetales siendo más frecuente la restricción del crecimiento fetal (p=0,37). Según la corionicidad, esta complicación se presentó en 50% (1/2) de los tricoriónicos, 16,6% (7/42) de los monocoriónicos y 11,3% (11/97) de los dicoriónicos. Conclusión: la restricción del crecimiento fetal fue el hallazgo más común en los embarazos múltiples en la población estudiada.

Influencia de factores no médicos para el nacimiento por cesárea en un hospital privado / Influence of non-medical factors for cesarean birth in a private hospital

Resumen: OBJETIVO: Encontrar los factores no médicos que intervienen en el criterio del obstetra para elegir que la vía de nacimiento sea por parto o cesárea. MATERIALES Y MÉTODOS: Estudio transversal, retrospectivo, observacional y analítico, efectuado en pacientes atendidas entre 2016 y 2019 en el Hospital Ángeles Lomas, con más de 24 semanas de embarazo y que lo terminaron mediante parto o cesárea. Criterio de exclusión: embarazos múltiples. Variable dependiente: nacimiento por parto o cesárea. Variables independientes: sexo del obstetra, consultorio en el mismo hospital o externo, disponibilidad de asistente médico, mes del año, día de la semana y periodo vacacional. RESULTADOS: Se incluyeron 3906 nacimientos, 1495 cesáreas (38.3%) y 2411 partos (61.7%). Se observó mayor riesgo de cesárea, con significación estadística en: nacimientos atendidos por obstetras externos (OR = 3.81; IC95%: 3.07-4.73), nacimientos atendidos por obstetras del mismo hospital sin asistente médico (OR = 1.75; IC95%: 1.48-2.08), obstetras mujeres (OR = 2.55; IC95%: 2.06-3.16), abril vs diciembre (OR = 1.44; IC95%:1.04-1.98) y miércoles vs domingos (OR = 1.55; IC95%:1.14-2.05). Se registraron más cesáreas en el periodo prevacacional vs vacacional (OR = 1.51; IC95%: 0.94-2.43) sin diferencia estadísticamente significativa. CONCLUSIONES: Existen factores no médicos que aumentan la frecuencia de cesárea. Los relacionados con el obstetra incluyen: no tener el consultorio en el mismo hospital y carecer de asistente médico.

Abstract: OBJECTIVE: To find the non-medical factors that intervene in the obstetrician's criteria for choosing a birth canal or Cesarean section. MATERIALS AND METHODS: Transversal, retrospective, observational and analytical study carried out on patients attended between 2016 and 2019 at Hospital Ángeles Lomas (Mexico City), with more than 24 weeks of pregnancy and who finished it by vaginal delivery or cesarean section. Exclusion criterion: Multiple pregnancies. Dependent variable: birth by delivery or cesarean section. Independent variables: sex of the obstetrician, office in the same hospital or outside, availability of medical assistant, month of the year, day of the week and vacation period. RESULTS: 3906 births, 1495 cesarean sections (38.3%) and 2411 deliveries (61.7%) were included. A higher risk of cesarean section was observed, with statistical significance in: births attended by external obstetricians (OR = 3.81; CI95%: 3.07-4.73), births attended by obstetricians at the same hospital without a physician's assistant (OR = 1. 75; CI95%: 1.48-2.08), female obstetricians (OR = 2.55; CI95%: 2.06-3.16), April vs. December (OR = 1.44; CI95%:1.04-1.98) and Wednesday vs More cesarean sections were recorded in the pre-vacation vs. vacation period (OR = 1.51; IC95%: 0.94-2.43) with no statistically significant difference. CONCLUSIONS: There are non-medical factors that increase the frequency of cesarean section. Those related to the obstetrician included: not having the office in the same hospital and not having a medical assistant.

An Observational Study on Uterine Myoma in Search of Factors Contributing to its Symptoms

Introduction: Uterine fibroid, the most common benign tumor,contributes significantly on quality of life if symptomatic.The study evaluates the factors which possibly contribute tothe symptoms. Objective: To identify the parameters whichpossibly play a role in symptoms of myoma.Material and Methods: An observational study on 48 subjectsafter taking written informed consent selected randomly fromwomen of reproductive age group attending at GynaecologyOut Patient Department.Results: Different age groups had comparable incidencesof fibroids. Most of the patients complained of Menorrhagia(54.2%). Metrorrhagia was complained in 6.2%, dysmenorrheain 10.4% patients, infertility and pain abdomen each wascomplained in 14.6% subjects. Most of the study subjectshad myoma of 14-week of gestation (39.6%) and 31.2% had16-week size myoma. The commonest location is found tobe fundo-anterior (33.3%), type is intramural (54.2%). Mostfibroids had volume of 95.1-125 cc (54.2%). One or twomyomas are more common than three or more myomas.Conclusion: Myoma is common in reproductive ages andthroughout the reproductive period incidences in differentage groups are comparable. Commonest symptom of myomais menorrhagia. Most myomas had volume of 95.1-125 cc,situated in fundo-anterior position, are of intramural type.Most myomas, if present as an abdominal lump, are of 14-week gravid uterus size. One or two myomas in uterus aremore common than number of myomas more than that

Multiple pregnancy: epidemiology and association with maternal and perinatal morbidity / Gestação múltipla: epidemiologia e associação com morbidade materna e perinatal

Abstract Twin pregnancy accounts for 2 to 4% of total births, with a prevalence ranging from 0.9 to 2.4% in Brazil. It is associated with worse maternal and perinatal outcomes. Many conditions, such as severe maternal morbidity (SMM) (potentially life-threatening conditions and maternal near-miss) and neonatal near-miss (NNM) still have not been properly investigated in the literature. The difficulty in determining the conditions associated with twin pregnancy probably lies in its relatively low occurrence and the need for larger population studies. The use of the whole population and of databases from large multicenter studies, therefore, may provide unprecedented results. Since it is a rare condition, it ismore easily evaluated using vital statistics from birth e-registries. Therefore, we have performed a literature review to identify the characteristics of twin pregnancy in Brazil and worldwide. Twin pregnancy has consistently been associated with SMM, maternal near-miss (MNM) and perinatal morbidity, with still worse results for the second twin, possibly due to some characteristics of the delivery, including safety and availability of appropriate obstetric care to women at a high risk of perinatal complications.

Resumo A gestação gemelar é responsável por 2 a 4% do total de nascimentos, com uma prevalência variando de 0,9 a 2,4% no Brasil. Ela é associada a piores resultados maternos e perinatais. Muitas condições, como amorbidade materna grave (condições potencialmente ameaçadoras da vida e near-miss materno) e near-miss neonatal ainda não foram investigadas de forma apropriada na literatura. A dificuldade na determinação de condições associadas com a gestação gemelar provavelmente reside em sua ocorrência relativamente baixa e na necessidade de estudos populacionais maiores. O uso da população total e de bancos de dados de grandes estudosmulticêntricos podem então fornecer resultados sem precedentes. Considerando que esta é uma condição rara, ela émais facilmente avaliada usando estatísticas vitais de registros eletrônicos de

Consecuencias y complicaciones de la amniocentesis. Experiencia de dos centros latinoamericanos de medicina materno fetal / Results and complications of amniocentesis. Experience of two centers of Latin American fetal maternal medicine

Resumen Objetivo Describir las indicaciones, complicaciones y repercusiones de la amniocentesis. Materiales y métodos Estudio descriptivo, observacional y transversal de las amniocentesis efectuadas de 2009 a 2015 en dos unidades de medicina materno fetal de Bogotá, Colombia. Se evaluaron las características de las pacientes, indicación de los procedimientos y las complicaciones. Además, los hallazgos se compararon con reportes de diferentes estudios de la bibliografía internacional. Resultados Se incluyeron 748 amniocentesis. La mediana de edad de las pacientes fue de 29 años (límites 23 y 37). La indicación más común fue el estudio genético en 508 casos (67.9%). Se reportaron 89 (17.5%) casos de cromosomopatías, y de éstas la de mayor frecuencia fue la trisomía 21 en 41 pacientes (46%). La mayor parte de las complicaciones se registró en embarazos que superaron las 20 semanas. La pérdida del embarazo y la amenaza de parto pretérmino atribuibles a la amniocentesis fueron de 0.9 y 2.5%, respectivamente. Conclusión Las características de la amniocentesis permitieron conocer sus repercusiones, complicaciones, tasa de pérdida real o factores asociados, con miras a explorar los factores maternos y fe tales en embarazos únicos y múltiples en dos unidades de Medicina Materno Fetal latinoamericanas.

Abstract Objective The purpose of this paper is to describe the indications, complications and results of amniocentesis performed in two fetal maternal medicine units in Bogota Colombia between 2009 and 2015. Materials and methods Cross-sectional observational descriptive study; 770 amniocentesis performed during 6 years (2009 - 2015) with evaluation of the characteristics of the patients, procedures and complications observed were evaluated. In addition, the findings were compared with reports from different studies of the world literature. Results 748 amniocentesis data were included, statistically analyzing the clinical characteristics of the patients and the results, indications and complications of the procedure. The median age was 29 years (RIQ: 23-37). The most common indication was genetic in 508 cases (67.9%). 89 (17.5%) cases of chromosomopathies were reported, with trisomy 21 being more frequently observed in 41 patients (46%). The loss of pregnancy and the threat of preterm labor attributable to amniocentesis were 0.94% and 2.54%, respectively. Conclusion The characteristics of amniocentesis allow us to know statistics of outcomes, complications, actual loss rate or associated factors, with a view to exploring both maternal and fetal factors in single and multiple pregnancies in two units of Latin American Fetal Maternal Medicine.

Consecuencias perinatales de embarazos logrados mediante reproducción asistida versus embarazos espontáneos / Perinatal results of pregnancy achieved by assisted reproduction therapy versus spontaneous pregnancy

Resumen OBJETIVO: Describir y comparar las consecuencias perinatales de los embarazos logrados por reproducción asistida versus espontáneos. MATERIALES Y MÉTODOS: Estudio observacional, transversal, retrospectivo y analítico. Se incluyeron pacientes que terminaron el embarazo en el Instituto Nacional de Perinatología Isidro Espinosa de los Reyes; se excluyeron las embarazadas con expediente clínico incompleto, terminación del embarazo antes de las 22 semanas. Se analizaron y compararon las principales consecuencias perinatales en ambos tipos de embarazos. El análisis de asociación entre terapia de reproducción asistida y complicaciones perinatales se hizo mediante una regresión logística simple y ajustada por variables confusoras. RESULTADOS: De 448 ciclos iniciados, se analizaron 98 embarazos únicos logrados por reproducción asistida; menor probabilidad para recién nacido pretérmino (p < 0.05) e ingreso a la unidad de cuidados intensivos neonatales (p <0.05) y embarazos múltiples; una probabilidad significativa de amenaza de parto pretérmino versus embarazos espontáneos (p < 0.05). CONCLUSIONES: Se registraron menos complicaciones perinatales en embarazos únicos por reproducción asistida y en embarazos múltiples mayor probabilidad de amenaza de parto pretérmino sin mayor prevalencia de recién nacido pretérmino. La adecuada atención multidisciplinaria previa a la concepción tiene mayor peso en las repercusiones perinatales que la técnica de fertilización asistida por sí misma.

Abstract BACKGROUND: As demand for assisted reproduction techniques has increased, so have concerns about associated perinatal outcomes and whether they are different from spontaneously achieved pregnancies. OBJECTIVE: to describe and compare perinatal outcomes of pregnancies achieved by assisted reproduction versus spontaneous pregnancies. MATERIALS AND METHODS: Observational, cross-sectional, retrospective, analytical study. Pregnancies with resolution within the institute were included; those with an incomplete clinical record, termination of pregnancy before 22 weeks were excluded. The main perinatal results in both types of pregnancies were analyzed and compared. The analysis of the association between assisted reproduction therapy and perinatal complications was made by a simple logistic regression and adjusted for confounding variables. RESULTS: Of 448 cycles initiated, 98 pregnancies achieved by assisted reproduction were analyzed, observing in single pregnancies; lower probability for preterm newborns (p <0.05) and admission to the neonatal intensive care unit (p <0.05) and in multiple pregnancies; a significant probability to present threat of preterm delivery versus spontaneous pregnancies (p <0.05). CONCLUSIONS: There were fewer perinatal complications in single pregnancies for assisted reproduction and in multiple pregnancies a greater probability of threat of preterm delivery without a higher prevalence of preterm newborn, concluding that having an adequate preconceptional multidisciplinary management has a greater weight in perinatal outcomes than Fertilization technique assisted by itself.

Características clínicas epidemiológicas de la retinopatía de la prematuridad en recién nacidos de embarazos múltiples / Clinical and epidemiological characteristics of retinopathy of prematurity in neonates born from multiple pregnancies

Introducción: las principales líneas del programa de Retinopatía de la Prematuridad en Cuba es la prevención de la ceguera por esta enfermedad y el tratamiento oportuno en los casos que lo requieran. Objetivo: determinar las características clínicas y epidemiológicas de la retinopatía de la prematuridad en el recién nacido de embarazos múltiples, sobre la base del programa nacional. Métodos: se realizó un estudio observacional descriptivo retrospectivo, entre enero de 1999 y diciembre de 2010, en el Hospital Universitario Materno Infantil Eusebio Hernández. Se incluyeron 52 recién nacidos de embarazos múltiples de menos de 35 semanas de edad gestacional, y bajo peso al nacer (£ 1 700 g). Las variables analizadas fueron: sexo, edad gestacional, peso, factores perinatales asociados con el desarrollo de la retinopatía y los estadios más frecuentes. Resultados: presentaron algún estadio de la retinopatía 9 recién nacidos para el 17,3 por ciento. Dentro de los bebés con retinopatía de la prematuridad, fueron más frecuentes el sexo masculino y el estadio I. El peso sobrepasó los 1 500 g y la edad gestacional estuvo entre 34 y 36 semanas. Los antecedentes que más incidieron en los recién nacidos con retinopatía fueron el uso de oxigeno y los esteroides. Conclusiones: la aplicación del programa permite detectar la aparición de la retinopatía del prematuro y tomar conductas adecuadas en la población en riesgo. Es necesario continuar la identificación de factores de riesgo potenciales de producir o empeorar la enfermedad

Introduction: the main lines of the retinopathy of prematurity program in Cuba are the prevention of blindness and the timely treatment of cases so requiring. Objective: to determine the clinical and epidemiological features of the retinopathy of prematurity in the neonate born to multiple pregnancies, according to the national program for this disease. Methods: aretrospective, observational and descriptive study conducted in the period of January 1999 to December 2010 at "Eusebio Hernandez" university infant and maternal hospital. It included 52 neonates born from multiple pregnancies, aged less than 36 weeks, and low birthweight (ú 1 700 g). The analyzed variables were sex, gestational age, weight, perinatal factors associated with the development of retinopathy, and the most frequent stagings. Results: nine babies presented some retinopathy staging (17,3 percent). In the group of babies with retinopathy of prematurity, males and staging I prevailed. The weight exceeded 1 500 g and the gestacional age was 34-36 weeks. The factors having the highest incidence on the newborns with retinopathy were the uses of oxygen and of steroids. Conclusions: the implementation of the program allows detecting the onset of retinopathy of prematurity and adopting adequate positions towards the risk populations. It is necessary to continue identifying potential risk factors that might cause or worsen the disease.

Reporte de tres casos de embarazo triple / Report of three cases of triple pregnancy

El embarazo múltiple (triple) es infrecuente (1 porciento), aunque su incidencia se ha incrementado en los últimos 15 años debido al empleo de los inductores de la ovulación y del desarrollo las técnicas de fertilización in vitro y transferencia de embriones, elevándose entre el 5 y 35 porciento. Continuamente conllevan una preocupación para el ginecobstetra por la morbimortalidad materna y perinatal, fundamentalmente debido a la prematuridad. El objetivo de este artículo es presentar tres casos de gestantes con embarazo triple y evolución favorable, ocurridos entre los años 2010 y 2011. Se revisó la literatura sobre el tema, se exponen brevemente las características clínicas de este embarazo, complicaciones, manejo y pronóstico; posteriormente se describieron los elementos significativos de estas pacientes atendidas en el Hospital Docente Ginecobstétrico Dr. Julio R. Alfonso Medina de Matanzas. Se realizan comentarios sobre los casos con opiniones de los autores revisados y de los autores del artículo; es frecuente el nacimiento por cesárea y pretérmino

Multiple (triple) pregnancies is rare (1 per cent), although its incidence has increased in the last 15 years due to the use of ovulation induction and the development of in vitro fertilization techniques and embryo transfer (5 and 35 per cent). These pregnancies continually involve a concern for the obstetrician due to maternal and perinatal morbidity and mortality, mainly due to prematurity. The objective of this paper is to present three cases of pregnant women with triple and favorable pregnancy, occurring from 2010 to 2011. Literature on the subject was reviewed. The clinical features of this pregnancy complications, management and prognosis are briefly described. Significant elements of these patients are then described. They were treated at the Dr. Julio R. Alfonso Medina Teaching Hospital in Matanzas. Preterm cesarean delivery is frequent. Comments on the cases with opinions of the revised authors and the authors of the article

Fetal Intra-Abdominal Umbilical Vein Varix in Monochorionic Twins: Is it Significant?

A 30-years-old Taiwanese female in her second pregnancy spontaneously conceived a monochorionic twin pregnancy. A routine ultrasound at 27 weeks of gestation revealed a selective intrauterine growth restriction (sIUGR) fetus and an appropriate gestational age (AGA) fetus. The AGA fetus was found to have a fetal intra-abdominal umbilical vein (FIUV) varix. Serial ultrasounds showed no changes in the FIUV varix. 2 weeks later, the pregnancy progressed to twin–twin transfusion syndrome (TTTS). Repeated amnioreductions were required at 29 and 30 weeks gestation. The babies were delivered by caesarean section at 31 weeks due to fetal distress in the sIUGR fetus. Both fetuses survived the neonatal period with problems of prematurity. The FIUV varix disappeared a few days after delivery.

A follow-up study on children conceived through intracytoplasmic sperm injection / 中华流行病学杂志

Objective To investigate the perinatal complications, birth defects and growth of children conceived through intracytoplasmic sperm injection (ICSI). Methods A total of 575 children conceived by ICSI in our reproductive medical center, were studied. The follow-up study would include items as pregnant complications, neonatal complications, birth defects in perinatal period, subsequently detected birth defects, body weight and body length/height growth. Results Prematurity and low birth weight of ICSI children were higher in the multiple births than in the singleton births. The rates of materal gestational hypertension, neonatal asphyxia, respiratory distress syndrome, infection diseases were higher in the multiple pregnancies than in the singleton pregnancies(P＜0.05). Eleven ICSI children had died. Ten of them died in the neonatal period and they were preterm infants. One fullterm singleton ICSI child died of hepatoblastoma at the age of 2. The rate of birth defects in perinatal period was higher in ICSI children of multiple pregnancies than in the general population (P＜0.05). The body weight and body length/height of most ICSI children had obtained the standard range between 1 to 3 year-olds. Conclusion The higher rates of perinatal complications in ICSI children were closely related to multiple pregnancies.

Vínculo de apego que establecen padres con hijos nacidos de embarazos múltiples / Attachment that parents establish with born children of multiple pregnancies

Objetivo: Describir el vínculo de apego que establecen los padres (madre-padre) con sus hijos nacidos de embarazos múltiples. Materiales y métodos: Investigación descriptiva de corte cualitativo. La muestra la conformaron seis parejas pertenecientes a los estratos 5 y 6 de la ciudad de Barranquilla (seis madres y seis padres) con hijos múltiples (2 parejas de gemelos y 4 de trillizos), cuyas edades oscilaron entre 0 y 3 años. Se diseñó una entrevista semiestructurada, que contenía las categorías de análisis: Aceptación, Disponibilidad y Expresión de sentimientos. Este instrumento fue sometido a un proceso de validación por parte de jurados expertos y a la aplicación de una prueba piloto. Resultados: Las madres describieron la maternidad múltiple como “única” y “especial”; sin embargo, tendieron a mostrar ansiedad, miedos y preocupaciones durante el embarazo ante la idea de gestar varios hijos a la vez. Las inquietudes giraban principalmente alrededor del tema de la salud física y cognitiva de sus hijos. Los padres vivenciaron la gestación con diversos temores asociados a la salud de sus compañeras e hijos, y describieron la experiencia como difícil y atemorizante. Conclusiones: Las madres tienden a idealizar la maternidad y su rol como cuidadoras mucho más que los padres, además se caracterizan por atención excesiva y ansiosa a los requerimientos de los hijos...

Objective: Characterize the link of attachment that parents (mother-father) establish with born children of multiple pregnancies. Materials and Methods: The design of the investigation was descriptive. Six couples belonging to the Colombia’s 5 and 6 strata (Colombian system of classification by economic status) from the city of Barranquilla (six mothers and six fathers) with multiple children (2 pairs of identical twins and 4 of triplets) whose ages ranged between 0 and 3 years of age. A semi-structured interview was designed, that contained the analysis categories: Acceptance, Availability, and Feelings expression. This instrument was submitted into a process of validation by part of the expert jury and to the application of a pilot test. Results: The mothers described the multiple maternity as unique and special. Nevertheless, they tended to show anxiety, fears and worries during the pregnancy before the idea of preparing several children simultaneously. The worries were turning principally about the topic of the physical and cognitive health of their children. The parents lived the gestation with diverse dreads associated with the health of their couple and children, and they described the experience as hard, difficult and terrorizing. Conclusions: The mothers tend to idealize maternity and their role as caretakers much more than fathers do; in addition they are characterized by excessive and anxious attention to the requirements of the children...

Embarazo múltiple: estudio de sus placentas / Multiple pregnancy: study of their placentas

Establecer las características de las placentas de los embarazos múltiples a las que se le realizó estudio de anatomía patológica en un período de 10 años. Se realiza la revisión de 112 informes de biopsias correspondientes a las placentas y sus anexos en embarazos múltiples: 104 gemelares y 8 triples, se establecen sus características normales y patológicas comparándose con la literatura nacional e internacional. Servicio de Anatomía Patológica. Maternidad "Concepción Palacios". La mayor frecuencia correspondió a placenta monocorial diamniótica, forma discoide, inserción paracentral del cordón; se encontraron alteraciones macro y microscópicas en concordancia con la literatura, así como tres casos de molas parciales, cuatro fetos papiráceos y tres fetos malformados entre otros hallazgos

To establish the characteristics of placentas from multiple pregnancies that underwent a pathological study in a period of 10 years. A review of 112 reports of biopsies from placentas and its annexes in multiple pregnancies was performed: twin 104 and 8 triples, sets out the normal and pathological features compared with the national and international literature. Department of Pathology. Maternidad "Concepcion Palacios". The highest frequency corresponded to placenta monochorionic diamniotic, discoid form, para central cord insertion, were macro and microscopic changes consistent with the literature and three cases of partial molas, four papyraceous fetuses and three malformed fetuses among other findings

Delayed-Interval Delivery after Cerclage Operation in a Case of Twin Pregnancy with One Fetal Delivery / 대한산부인과학회지

With delayed childbearing and increased use of ovulation-stimulating drugs and assisted reproductive technologies (ART), the incidence of multiple pregnancies has increased dramatically in the past 20 years. One of the most common and serious complications of multiple pregnancies is preterm delivery. The delivery of the initial fetus in a multiple gestation usually is followed by the delivery of the subsequent fetus or fetuses shortly there after. However, a few successful delayed-interval deliveries have been reported since the first case in 1880 by Carson. Since that time, an interest in delayed-interval delivery has been developed and spurred by the increased prevalence of multiple gestations and preterm deliveries associated with these pregnancies. We report a case of a delayed-interval delivery in a twin pregnancy with an interval of 71 days. This case is the longest interval case and the fisrt delayed-interval delivery in monochorionic twin in Korea.