The efficacy of muscle function training combined with occlusal inducer in the treatment of malocclusion in children with OSA / 临床耳鼻咽喉头颈外科杂志

Objective:This study aims to investigate the clinical effectiveness of muscle function training combined with occlusal inducers in the treatment for children's malocclusion after obstructive sleep apnea（OSA） surgery. Methods:A total of 40 pediatric patients who underwent surgery for OSA at Shanghai Children's Medical Center, affiliated with Shanghai Jiao Tong University School of Medicine, from January 2020 to December 2021 were involved in this study. They were divided into a treatment group（n=20） and a control group（n=20）. The treatment group received muscle function training combined with occlusal inducers, while the control group received muscle function training alone. Cephalometric measurements of hard tissues were compared between the two groups before and 12 months after surgery. Additionally, the OSA-18 questionnaire, which includes 18 items to assess the life quality of children with OSA, was filled out before surgery, 6 months after surgery, and 12 months after surgery by these patients. Results:①The scores of sleep disorders, physical symptoms, emotional status, daytime sleepiness and energy status and the degree of influence on guardians in the two groups were significantly improved at 12 months after operation（P<0.05）. The scores of sleep disorders, physical symptoms, emotional status and the degree of influence on guardians in the treatment group were better than those in the control group（P<0.05）. ②Cephalometric data at 12 months after operation showed that the upper and lower alveolar seat angle（ANB）, Overbite, upper and lower central incisor angle（U1-L1） and Overjet in the treatment group were lower than those in the control group at 12 months after operation, and the difference was statistically significant（P<0.05）. Conclusion:Children with OSA can improve the dentition irregularity by muscle function training combined with occlusal inducer after operation, and the effect is better than that of muscle function training alone.

Does photobiomodulation improve muscle performance and recovery? a systematic review / ¿la fotobiomodulación mejora el desempeño y la recuperación muscular? una revisión sistemática / A fotobiomodulação melhora o desempenho e a recuperação muscular? uma revisão sistemática

ABSTRACT Photobiomodulation (PBM) appears to limit exercise-induced muscle damage, improve biochemical and functional recovery, and reduce inflammation and oxidative stress. This systematic review aimed to evaluate the effectiveness of photobiomodulation (PBM) in skeletal muscle recovery after exercise, addressing the different types of lasers and parameters used. Randomized clinical trials (RCTs) comparing the effects of PBM were included. The primary outcome evaluated was performance, and the secondary was inflammatory marker expression. The searches were conducted in March 2021. Fifteen RCTs that met the inclusion criteria were included. There was significant variability regarding the doses and wavelengths used, as well as in the types of lasers. However, in most studies, PBM promoted improvement of maximum voluntary contraction, better oxygen consumption, increased time to achieve exhaustion and fatigue, and decreased creatine kinase (CK), oxidative stress, and fatigue markers, mainly when used before exercise. Photobiomodulation applied before exercise, regardless of variations in doses and wavelengths, improves muscle performance and decreases levels of inflammation and fatigue markers. Evidence level II; Systematic review of level II studies.

RESUMEN La fotobiomodulación (PBM) parece aliviar el daño muscular inducido por el ejercicio, mejorando la recuperación bioquímica y funcional y reduciendo la inflamación y el estrés oxidativo. Esta revisión sistemática tuvo como objetivo evaluar la eficacia de la fotobiomodulación (PBM) en la recuperación del músculo esquelético después del ejercicio, abordando los diferentes tipos de láseres y parámetros utilizados. Se incluyeron ensayos clínicos aleatorizados (ECA) que compararon los efectos de la PBM. El resultado primario evaluado fue el desempeño y el secundario fue la expresión de marcadores inflamatorios. Se analizaron los estudios publicados hasta marzo de 2021. Resultados: Se incluyeron quince ensayos clínicos aleatorizados que cumplían los criterios de inclusión. Hubo una importante variabilidad en cuanto a las dosis y longitudes de onda utilizadas, así como al tipo de láser. Sin embargo, en la mayoría de los estudios, la PBM promovió una mejor contracción voluntaria máxima, un mejor consumo de oxígeno, un mayor tiempo para alcanzar el agotamiento y la fatiga, y una disminución de los niveles de creatina quinasa (CK), del estrés oxidativo y de los marcadores de fatiga, especialmente cuando se utiliza antes del ejercicio. La fotobiomodulación aplicada antes del ejercicio, a pesar de presentar gran variabilidad de dosis y longitudes de onda, ha demostrado mejorar el desempeño muscular y disminuir los niveles de marcadores inflamatorios y de fatiga. Nivel de evidencia II; Revisión sistemática de estudios de nivel II.

RESUMO A fotobiomodulação (PBM) parece amenizar o dano muscular induzido pelo exercício, melhorando a recuperação bioquímica e funcional e reduzindo a inflamação e o estresse oxidativo. Esta revisão sistemática teve como objetivo avaliar a eficácia da fotobiomodulação (PBM) na recuperação do músculo esquelético depois do exercício, abordando os diferentes tipos de lasers e parâmetros utilizados. Foram incluídos estudos clínicos randomizados (RCTs) que comparam os efeitos da PBM. O desfecho primário avaliado foi o desempenho e o secundário foi a expressão de marcadores inflamatórios. Foram analisados estudos publicados até março de 2021. Foram incluídos 15 RCTs que atenderam aos critérios de inclusão. Houve variabilidade significativa quanto às doses e comprimentos de onda usados, bem como aos tipos de laser. Porém, na maioria dos estudos, a PBM promoveu melhora da contração voluntária máxima, melhor consumo de oxigênio, aumento do tempo para atingir exaustão e fadiga, e diminuição dos níveis de creatina quinase (CK), estresse oxidativo e marcadores de fadiga, principalmente quando usado antes do exercício. A fotobiomodulação aplicada antes do exercício, apesar de apresentar grande variabilidade de doses e comprimentos de onda, melhora o desempenho muscular e diminui os níveis de marcados inflamatórios e de fadiga. Nível de evidência II; Revisão sistemática de estudos de Nível II .

The correlation between blood glucose level and muscle mass, strength and function in an elderly population / 中华内科杂志

Objective:To explore the correlation between blood glucose levels and the three factors of sarcopenia (muscle mass, strength and function) in older Chinese community dwellers.Methods:This is a retrospective study conducted by collecting the data of patients in Jiangsu Huaqiao Road Community Health Service Center from 2018 to 2019. Two hundred and fifty people aged 60 years or elder were selected. Among them, 101 were men and 149 were women. According to the American Diabetes Association diagnostic criteria for diabetes mellitus in 2018, they were divided into normal glucose tolerance (NGT) group, pre-diabetes group and diabetes group. The patients were assessed for sarcopenia as well.Results:Compared with those in the NGT group, muscle mass and upper limb muscle strength did not change in the diabetic group, but lower limb muscle strength and body function [walking speed, balance, short physical performance battery (SPPB)] decreased significantly in the diabetic group. Pearson correlation analyses showed that fasting plasma glucose(FPG) was negatively correlated with walking speed ( r=-0.248, P=0.001), three-pose balance ( r=-0.166, P=0.013) and SSPB ( r=-0.213, P=0.001). Glycosylated hemoglobin A1c(HbA1c) was positively correlated with sitting and standing time ( r=0.205, P=0.002), and negatively correlated with three-pose balance ( r=-0.186, P=0.006) and SSPB ( r=-0.154, P=0.024). Multiple regression analyses showed that FPG was negatively associated with walking speed (β=-0.125, P=0.005) and SPPB (β=-0.034, P=0.012), and that HbA1c was positively associated with sitting and standing time (β= 0.218, P =0.006) and negatively associated with three-pose balance (β=-0.143, P=0.012), and SPPB (β=-0.117, P =0.036). Conclusions:There is no significant correlation between blood glucose levels and muscle mass in the elderly; however, FPG is closely correlated with gait speed, and HbA1c is closely correlated with muscle strength of lower limbs and balance ability in the elderly.

The role of the gut microbiota in the pathogenesis of sarcopenia / 中华老年医学杂志

Sarcopenia is a progressive syndrome associated with aging, generalized loss of skeletal muscle mass, muscle strength and function.It is closely related to the occurrence of adverse events such as ambulatorydysfunction, falls and fractures in the elderly, and seriously affects the quality of life of the elderly.The etiology of sarcopenia has not been fully elucidated.Various pathophysiological mechanisms such as reduced exercise, genetic factors, age-related hormone changes, malnutrition and insufficient protein intake, decreased neuromuscular function, pro-inflammatory cytokines, and myocyte apoptosis are possible factors.Recent studies have found that intestinal microecological changes may be implicated in the occurrence and development of sarcopenia.In this article, we reviewed intestinal microecological changes and their possible role in the mechanisms underlying sarcopenia.

Analysis of the characteristics of sarcopenia in elderly patients of different age groups / 中华老年医学杂志

Objective:To compare clinical characteristics and results on parameters for muscle measurement in elderly sarcopenia patients of different age groups.Methods:This was a cross-sectional study, and 404 outpatients aged 60 years and over were enrolled and received a long-term follow-up.According to the World Health Organization classification of the elderly, the subjects were divided into a youngest-old group, a middle old group and an oldest-old group; and according to the diagnostic criteria of the Asian Working Group for Sarcopenia in 2019, elderly people of all ages were divided into a sarcopenia group and a non-sarcopenia group.General clinical data were recorded, and the upper arm circumference, leg circumference, skeletal muscle index, grip strength and walking speed, the Short Physical Performance Battery and timed up and go were conducted.At the same time, the body composition was measured by multifrequency bioelectrical impedance analysis.Results:The subjects had a mean age of(85.24 ± 8.23)years, including 90(22.28%)youngest-old, 165(40.84%)middle old and 149(36.88%)oldest-old.123 patients(30.45%)were diagnosed with sarcopenia, with a prevalence of 27.78%(25)in the youngest-old group, 28.48%(47)in the middle old group and 34.23%(51)in the oldest-old group.Compared with those without sarcopenia, the basal metabolic rate in sarcopenia patients of all age groups decreased significantly, the levels of hemoglobin and albumin in youngest-oldsarcopenia patients decreased, the waist circumference and body mass index in middle old and oldest-old sarcopenia patients decreased, and the body fat rate in middle old sarcopenia patients increased.In the subjects with sarcopenia, the proportion of men in the oldest-old group was higher than in the other two groups.Compared with the youngest-old group, the levels of alanine aminotransferase and prealbumin decreased, serum creatinine increased, and skeletal muscle index values did not change in the middle old and longest-old groups, but handgrip strength(27.7±5.9 vs.23.2±6.9 vs.21.4±5.8, F=5.81, P=0.004), gait speed(0.8±0.2 vs.0.7±0.2 vs.0.5±0.2, F=11.88, P=0.000)and calf circumference(33.4±3.3 vs.15.9± 8.4 vs.31.5±3.1 vs.30.9±3.3, F=3.58, P=0.031)significantly decreased, and time up and go values(10.0±2.1 vs.15.9±8.4 vs.20.8±12.8, F=6.98, P=0.001)increased in the middle old and longest-old groups.Partial correlation analysis showed that age had a significant negative correlation with handgrip( r=-0.374, P=0.001), daily gait speed( r=-0.441, P=0.000), and calf circumference( r=-0.223, P=0.017), but a significant positive correlation with timed up and go( r=0.319, P=0.009). Conclusions:Compared with youngest-old sarcopenia patients, middle old patients show significant decline in muscle function, muscle strength and muscle mass in the lower limb.With increasing age, the impact of changes in muscle function, muscle strength and regional muscle mass on adverse events should receive heightened attention.

Effects of multicomponent training on nutritional status and muscle function in frail elderly adults / 中国实用护理杂志

Objective:To investigate the effect of multicomponent training on nutritional status and muscle function in older adults with frailty syndrome.Methods:A total of 120 elderly patients with frailty syndrome of Elderly Diagnosis and Treatment and Physical Examination Center,Jiangsu Provincial People′s Hospital from June 2018 to December 2019 were randomly divided into observation group and control group, each contained 60 cases. The control group received routine nursing care. On the basis of these, the observation group was given multicomponent training. The nutritional status, frailty status and muscle function were compared between two groups before and after 12 weeks of intervention.Results:Before intervention, there was no significant difference in the nutritional status, degree of frailty and muscle function between the two groups ( P>0.05). After intervention, the protein, skeletal muscle and total plasma protein, serum albumin, serum prealbumin and transferrin were (7.55 ± 1.34) kg, (21.37 ± 2.41) kg, (61.97 ± 5.69) g/L, (229.05 ± 17.67)mg/L, (42.14 ± 4.83) g/L, (2 364.29 ± 296.31) mg/L in the observation group, significantly higher than those in the control group (6.92 ± 0.97) kg, (20.31 ± 2.04) kg, (57.96 ± 5.22) g/L, (210.15 ± 27.99) mg/L, (37.66 ± 5.75) g/L, (2 247.42 ± 267.39) mg/L, the differences were statistically significant ( t values were 2.19-4.47, P<0.05). After intervention, the scores of physical, psychological and total frailty were 6.03 ± 0.71, 2.46 ± 0.73, 9.63 ± 0.99 in the observation group, significantly higher than in the control group (6.45 ± 0.95) pionts, (2.71 ± 0.52) pionts, (10.34 ± 1.20) pionts, the differences were statistically significant ( t=2.67, 2.02, 3.39, P<0.05). After intervention, the side-by-side, full-tandem, 4-m walk, repeated chair stands scores and total Short Physical Performance Battery (SPPB) scores were (0.87 ± 0.28) pionts, (1.65 ± 0.29) pionts, (2.09 ± 0.47) pionts, (1.93 ± 0.49) pionts, (7.36 ± 0.75) pionts, those socres were (0.72 ± 0.31) pionts, (1.50 ± 0.31) pionts, (1.87 ± 0.61) pionts, (1.70 ± 0.62) pionts, (6.55 ± 0.89) pionts in the control group, the differences were statistically significant ( t values were 2.16-5.18, P<0.05). Conclusions:Multicomponent training can improve the nutritional status and muscle function and delay the progress of frailty in elderly in elderly patients.

Effect of moxibustion on postpartum urodynamics and pelvic floor function in puerperal women / 中国针灸

OBJECTIVE@#To observe the effect of moxibustion on postpartum urodynamics and recovery of pelvic floor function based on the pelvic floor muscle function training.@*METHODS@#A total of 150 puerperal women were randomly divided into an observation group (75 cases, 15 cases dropped off) and a control group (75 cases, 15 cases dropped off). The control group was treated with pelvic floor muscle function training, twice a day. Based on the treatment in the control group, the observation group was treated with @*RESULTS@#Compared before treatment, the levels of FUL, MUCP, BC, Pdet Qmax and SLPP in the observation group after treatment were increased (@*CONCLUSION@#The moxibustion combined with pelvic floor muscle function training could improve postpartum urodynamics and pelvic floor muscle strength.

Factors influencing respiratory muscle dysfunction among stroke survivors / 中华物理医学与康复杂志

Objective:To analyze the respiratory muscle functioning of stroke survivors and explore factors influencing it so as to provide references for clinical rehabilitation intervention.Methods:A total of 139 stroke survivors were randomly divided into a respiratory muscle dysfunction group and a control group based on the actual strength of their inspiratory muscles divided by the predicted strength. Beyond typical clinical data, information was collected about the subjects′ exercise habits. Balance ability was evaluated using the Fugl-Meyer assessment scale (FMA) and the simplified Berg Balance Scale (BBS). Multivariate logistic regression was used to analyze the factors influencing respiratory muscle dysfunction.Results:Among the 139 patients, 81 (58.27%) had respiratory muscle dysfunction. Univariate analysis showed that patients with stroke in the brainstem and dysphagia and those with poor FMA and BBS scores were at significantly greater risk of respiratory muscle dysfunction. Logistic regression analysis showed that dysphagia, FMA and BBS scores were factors independently predicting respiratory muscle dysfunction among stroke survivors, with dysphagia as a risk factor, and high FMA and BBS scores as protective factors.Conclusion:Some stroke survivors may have respiratory muscle dysfunction, and dysphagia is a risk factor, while the high FMA and BBS scores are protective.

Effects of Vibration Training with Adjusted Frequency on Functional Ankle Instability / 医用生物力学

Objective To study the effect of vibration training with adjusted frequency on changes in explosive force of lower limbs, balance and muscle function around ankle joints of patients with functional ankle instability (FAI), so as to provide an empirical basis for rehabilitation training of FAI patients in clinic. Methods Twenty-six FAI patients were randomly divided into the experimental group (n=14) and the control group (n=12). The experimental group received 8-week rehabilitation training with vibration intervention, while the control group only received 8-week rehabilitation training. Changes in maximum power, average power, maximum speed and average speed of the injured limb during vertical jump with single leg, changes in distances during long jump, changes in time during one-leg standing with eyes open and closed，changes in contract time (tc), relax time (tr) and displacement (Dm) of medial gastrocnemius (GM), lateral gastrocnemius (GL) and tibialis anterior (TA) muscles before and after training were measured and compared. Results In the experimental group, the maximum power and maximum speed of the injured limb during vertical jump with single leg, the distance during long jump with single leg and the time during one-leg standing with open and closed eyes were significantly improved, and the increase was higher than that of the control group. The increase of tc of all muscles in the experimental group was smaller than that of the control group, but tr and Dm did not show any regularity. Conclusions Vibration training with adjusted frequency can effectively improve the explosive force and balance ability of lower limbs of FAI patients, and promote the tc shortening of GL, GM and TA muscles, but whether vibration training with adjusted frequency can reduce muscle tension and promote muscle relaxation is still not clear.

Evaluation of Unilateral Masticatory Muscle Function by Comprehensive Intervention / 中山大学学报(医学科学版)

@#【Objective】 To compare the changes of electromyographic activity of masticatory muscles in unilateral chewers before and after comprehensive intervention，and to evaluate the effect of comprehensive intervention.【Methods】 Thirty patients with unilateral mastication were selected，aged（19.3±0.5）years old. There was no statistically significant difference in general conditions ，which met the selection criteria for unilateral mastication. Randomly divided into intervention group and control group，with 15 cases in each group. The control group did not undergo any treatment，and the intervention group was given comprehensive intervention treatment mainly by eliminating inducement and muscle function training. Six months later，the electromyogram of masseter（left：LMM，right：RMM）and anteriovent of digastric muscle（left：LDA，right：RDA） were recorded in the two groups during the maximum opening and closing movement（M1）and masticatory movement（M2）. Statistical analysis was performed for the above.【Results】① There were significant differences in the average electromyographic difference values of LDA［M1：-7.4（-12.98，-1.84）］and RMM［M2：-2.28（- 4.42，- 0.13）］before and after intervention in the intervention group（P < 0.05）；the average EMG values of RMM and RDA in M2 after intervention were 9.62（5.99，9.98），9.96（7.91，12.62），compared with RMM［4.88（3.87~5.88）］，RDA［5.05（3.07~8.12）］in control group，the difference was statistically significant（P < 0.01）. ② The peak electromyogram values of bilateral DA （M1） and MM （M2） in intervention group were higher than those before intervention （P < 0.05）；the peak electromyogram values of LDA（M1）after intervention was 760.24（322.34~953.81），compared with LDA［M1 ：317.41（186.17~474.81）］in the control group，the difference was statistically significant（P < 0.05）.③ The activity asymmetry index of MM and DA in intervention group was lower than that before intervention（P < 0.05）；the value of the MM index［M1（15.59 ± 10.52），M2（10.84 ± 7.35）］after the intervention was lower than that in control group［M（129.89 ± 20.56），M（222.39 ± 16.87）］（P < 0.05），the DA index value［M1：7.60（5.00~26.5）］was lower than that in control group［25.4（13.8~43.50）］（P < 0.05）.【Conclusions】After comprehensive intervention，the contractility and symmetry of masseter and anteriovent of digastric muscle were significantly improved ，and the function of masticatory muscles recovered well.

Progress on the Muscle Function Evaluation and Its Forensic Application / 法医学杂志

Accurate evaluation of muscle function helps to understand the recovery of muscle, bone, nervous system diseases or injuries, especially for muscle dysfunction caused by peripheral nerve injury.Therefore, the methods of muscle function evaluation have been the focus of researchers, with new methods having been constantly proposed.Muscle strength testing is an important part of muscle function evaluation.Besides hand muscle strength assessment, currently used muscle function assessments include simple instrumental test, isokinetic muscle test, electrophysiological test, etc.In addition, the application of needle electromyography, motor unit number estimation, motion unit index in muscle function evaluation has also been reported for several times.This paper reviews the research progress and practical application of these methods.

Effect of group management mode on compliance of pelvic floor function exercise for patients with post ;partum urinary incontinence / 中国实用护理杂志

Objective To explore the effect of group management mode on compliance of pelvic floor function exercise for patients with post partum urinary incontinence (PPUI). Methods A total of 80 cases of patients with PPUI were randomly divided into the observation group and the control group. Patients in the control group received one-to-one routine health guidance. Patients in the observation group received group management mode including special subject teaching guidance, induction and communication between patients. Three months after the intervention, two groups of patients were evaluated at six months after postpartum by the pelvic floor muscle strength, one-hour urine pad test and pelvic floor muscle function exercise compliance. Results Six months after postpartum, the cure rate of the pelvic floor muscle strength was 100%(40/40) for typeⅠmuscle, 100%(40/40) for typeⅡmuscle in the observation group. In the control group, the cure rate for typeⅠmuscle was 70%(28/40) and 65%(26/40) for type Ⅱmuscle. The difference between these two groups was statistically significant (χ2=14.118, 16.970, P=0.000). The total effective rate of urinary incontinence was 100.0%(40/40) in the observation group, 67.5% (16/40) in the control group, and there was statistical significance (χ2=25.232, P=0.000). Evaluation of the compliance of pelvic floor function exercise showed that the rates were 72.5% (29/40) for complete compliance, 27.5%(11/40) for incomplete compliance and 0 for total non-compliance in the observation group. In the control group, these rates were 2.5%(1/40), 55.0%(22/40), 42.5%(17/40). And there was statistical significance as well (χ2=54.847, P=0.000). Conclusions Group management mode can improve the compliance of pelvic floor muscle function exercise and the strength of pelvic floor muscle, and improve the degree of urinary incontinence in postpartum patients with urinary incontinence.

Evaluation of papillary muscles function in myocardial infarction patients using 2D speckle tracking imaging / 中华超声影像学杂志

Objective To investigate papillary muscle function and construction in myocardial infarction(MI) patients by two-dimensional speckles tracking imaging(2D-STI),and to analyze the influence factors of ischemic mitral regurgitation.Methods Fifty myocardial infarction with ischemic mitral regurgitation(IMR) patients were brought into case group.The patients were divided into two groups:Ant MI group and Inf-Pos-MI group.Forty-five health volunteers were involved as control group.Anterior,posterior papillary muscle longitudinal strain (ALS,PLS),delay time(DT),fractional shortening (FS),length between the posterior or anterior papillary muscle tips and the contralateral anterior mitral annualr (APM AMA,PPM AMA),mitral leaflet closure (MLC),inter distance papillary muscle (IPMD) were aquired respectively.Papillary muscle function and construction among the groups were compared,and the effective factors of IMR were evaluated.Results Between the control group and Ant-MI group,the left ventricular end-diastolic diameter(LVEDD),left ventricular end-diastolic and end-systolic volume(LVEDV,LVESV),left ventricular ejection fraction(LVEF),ALS,delay time(DT),A FS,IPMD,MLC,APM-AMA,PPM-AMA were significantly different(all P ＜0.05).Between the control group and Inf-Pos-MI group the LVEDD,LVEDV,LVESV,EF,DT,PPM-AMA,MLC,PLS,P-FS were significantly different(P ＜0.05).Between the Ant-MI group and Inf-Pos-MI group,the LVEDD,LVEDV,LVESV,EF,MLC,ALS,PPM-AMA,PLS were significantly different (all P ＜ 0.05).In the Ant-MI group,LVEDV,ALS,MLC were significantly correated with Gensini score(r =0.71,-0.65,0.56;P ＜0.05).In the Inf-Pos-MI group,PPM AMA,PLS were significantly correated with Gensini score(r =0.65,-0.76;P ＜0.05).In the Ant MI group and Inf-Pos-MI group,the ALS,PLS,PPM-AMA were significantly different (P ＜ 0.05).Its correlates in Logistic analysis of Ant-MI group included LVEDV,MLC,DT with OR 1.48,1.72,1.54(P ＜0.05),respectively.Its correlates in logistic analysis of Inf Pos-MI group included PLS,PPM-AMA,DT with OR 1.78,1.57,1.56 (P ＜0.05),respectively.Conclusions There are different extent of damage of papillary muscle function and construction in Ant-MI group and Inf-Pos-MI group.The increases of LVEDV and MLC and desynchronization of PMs are risk factors of IMR in Ant-MI group.The increases of PMP-AMA,decrease PLS and desynchronization of PMs are risk factors of IMR inInf-Pos-MI group.

Effect of pelvic floor muscle rehabilitation training combined with Buzhong Yiqi Pill at ultra-early stage on the recovery of pelvic floor muscle function after delivery / 中国生化药物杂志

Objective To observe the effect of pelvic floor muscle rehabilitation training combined with Buzhong Yiqi Pill at ultra-early stage or early stage on the recovery of postpartum pelvic floor muscle function, to explore the feasibility of intervention of postpartum rehabilitation training at ultra-early stage. Methods 314 patients were randomly divided into the ultra-early stage group and the early stage group, 157 cases for each group. Patients in the ultra-early group were guided to give Kegel exercise and the biofeedback electrical stimulation therapy in the seventh week combined with Buzhong Yiqi pill in 1-2 days after delivery , patients in the early group were given Kegel exercise and biofeedback electrical stimulation therapy in the seventh week combined with Buzhong Yiqi pill. Effects of treatment two groups were observed. Results There were significant increased in pelvic floor muscle activity compared with six weeks and 2 days after delivery between two groups (P<0.05), and there were significant increased in the ultra-early group compared with the same period in the early group (P<0.05) . There were significant increased in good rate in 12 weeks after delivery compared with immediate time and 2 days after delidery (P<0.05), and more significant increased in the ultra- early group than that in the early group (P<0.05). There were significant decreased in urinary urgency, lumbosacral painand tenesmus, vaginal relaxation, and vaginal dryness rate in 12 weeks after delivery compared between two groups (P<0.05). Conclusion There were good effects in pelvic floor muscle rehabilitation training combined with Buzhong Yiqi Pill at ultra-early stage on the recovery of pelvic floor muscle function after delivery, and be worthy of clinical application.

Poor muscle strength and function in physically inactive childhood-onset systemic lupus erythematosus despite very mild disease / Redução na força muscular e capacidade funcional em pacientes fisicamente inativos com lúpus eritematoso sistêmico de início juvenil, apesar de doença muito leve

ABSTRACT Objective: To compare muscle strength (i.e. lower- and upper-body strength) and function between physically inactive childhood-onset systemic lupus erythematosus patients (C-SLE) and healthy controls (CTRL). Methods: This was a cross-sectional study and the sample consisted of 19 C-SLE (age between 9 and 18 years) and 15 CTRL matched by age, sex, body mass index (BMI), and physical activity levels (assessed by accelerometry). Lower- and upper-body strength was assessed by the one-repetition-maximum (1-RM) test. Isometric strength was assessed through a handgrip dynamometer. Muscle function was evaluated by the timed-stands test (TST) and the timed-up-and-go test (TUG). Results: When compared with CTRL, C-SLE showed lower leg-press and bench-press 1-RM (p = 0.026 and p = 0.008, respectively), and a tendency toward lower handgrip strength (p = 0.052). C-SLE showed lower TST scores (p = 0.036) and a tendency toward higher TUG scores (p = 0.070) when compared with CTRL. Conclusion: Physically inactive C-SLE patients with very mild disease showed reduced muscle strength and functionality when compared with healthy controls matched by physical activity levels. These findings suggest C-SLE patients may greatly suffer from a physically inactive lifestyle than healthy controls do. Moreover, some sub-clinical “residual” effect of the disease or its pharmacological treatment seems to affect C-SLE patients even with a well-controlled disease.

RESUMO Objetivo: Comparar a força muscular (ou seja, a força muscular dos membros superiores e inferiores) e a capacidade funcional de pacientes fisicamente inativos com lúpus eritematoso sistêmico de início juvenil (LESJ) com controles saudáveis (CTRL). Métodos: Estudo transversal cuja amostra foi composta por 19 pacientes com LESJ (entre 9 e 18 anos) e 15 CTRL pareados por idade, sexo, índice de massa corporal (IMC) e nível de atividade física (avaliada através do uso de acelerômetros). A força dos membros superiores e inferiores foi avaliada pelo teste de uma repetição máxima (1-RM). A força isométrica foi avaliada através do uso de um dinamômetro. A capacidade funcional foi avaliada pelo Timed-stands test (TST) e Timed-up-and-go test (TUG). Resultados: Quando comparados com os CTRL, os pacientes com LESJ apresentaram menor força em 1-RM no Leg press e supino (p = 0,026 e p = 0,008, respectivamente) e uma tendência a menor força de preensão manual (p = 0,052). Os pacientes com LESJ apresentaram menores escores no TST (p = 0,036) e uma tendência a maior pontuação no TUG (p = 0,070), quando comparados com o grupo CTRL. Conclusão Pacientes com LESJ, fisicamente inativos, com doença muito leve mostraram redução na força muscular e capacidade funcional quando comparados com controles saudáveis pareados por níveis de atividade física. Esses achados sugerem que pacientes com LESJ podem apresentar mais efeitos deletérios por manter um estilo de vida fisicamente inativo do que controles saudáveis. Além disso, alguns efeitos “residuais” subclínicos da doença ou do tratamento farmacológico parecem afetar pacientes com LESJ, mesmo com uma doença bem controlada.

Utilidad de la dinamometría en pacientes en hemodiálisis / Use of dynamometry in hemodialysis patients

INTRODUCCIÓN: La dinamometría es un método de evaluación de la fuerza muscular (FM) reproducible, barato y sencillo, que en conjunto con otras determinaciones presenta alta sensibilidad y especificidad en la detección precoz de variaciones en el estado nutricional. OBJETIVOS: Evaluar factores relacionados con disminución de la FM en pacientes en hemodiálisis (HD).MATERIAL Y MÉTODOS: Se realizó un estudio de corte transversal, unicéntrico. Se analizaron variables clínicas: sexo, edad, tensión arterial, peso, pérdida de peso significativa a los 3 y 6 meses previos, índice de masa corporal (IMC), ganancia interdialítica, tiempo en HD, condición de diabético, ingesta energética y proteica, de laboratorio (hemoglobina, hepatograma, ionograma, calcio, fósforo, lipidograma, proteinograma, transferrina) y fuerza prensil (pre y posdiálisis y en ambos brazos) medida por dinamometría. Se compararon los valores de FM con los de una población sana, considerando como alterados aquellos por debajo del percentilo 10. Se consideró promedio, mediana, desvío estándar y análisis mediante test de Student y Chi cuadrado según correspondiera. Se consideró significativo una p<0.05. RESULTADOS: Participaron 73 pacientes. Un 47.95% presentó baja FM con una significativa disminución de fuerza entre el brazo del acceso vascular y el contralateral (p 0,00019). De las variables estudiadas, el mayor tiempo en HD (p 0,026), menor IMC (p 0,046) tuvieron diferencia significativa entre los que tuvieron FM normal vs disminuida. Conclusiones: La disminución de la FM en pacientes en HD es muy frecuente y se relacionó con mayor tiempo en HD y menor IMC

INTRODUCTION: Dynamometry is a cheap, simple and easily reproduced method to assess muscle strength (MS), which, like other processes of obtaining measurements, displays high sensitivity and specificity for the early detection of any change in the nutritional status. OBJECTIVES: To evaluate factors concerning the reduction in MS in patients undergoing hemodialysis (HD). METHODS: A single center, cross-sectional study was carried out. The following clinical variables were analyzed: sex, age, blood pressure, weight, significant weight loss within the last 3 6 months, body mass index (BMI), weight gain in between dialysis sessions, hemodialysis treatment time, diabetes, energy and protein intake. Other factors taken into account were: laboratory findings (hemoglobin, hepatogram, electrolyte panel, calcium test, phosphate test, lipid profile, protein analysis, transferrin saturation) and hand grip strength (before and after dialysis, on both arms) measured through dynamometry. The patients' muscle strength values were compared to those of healthy subjects. Values below the 10th percentile were regarded as abnormal. Mean, median, standard deviation as well as the X2 and the Student's t tests were considered where applicable. A p<0.05 constituted a significant value. RESULTS: There were 73 patients included in this study and 47.95% of them showed low MS with significant strength loss on the arm having the vascular access when compared to the other arm (p 0.00019). A longer hemodialysis treatment time (p 0.026) and a lower BMI (p 0.046) were found to be the two variables with the highest impact on MS. CONCLUSIONS: Muscle strength loss in patients undergoing hemodialysis is very common and is associated with a longer HD treatment time and a lower BMI

Improvement of postpartum pelvic floor by rehabilitation training assessed with transperineal real -time ultrasound / 中华超声影像学杂志

Objective To investigate the improvement of postpartum pelvic floor by rehabilitation training assessed with three-dimensional transperineal ultrasound . Methods One hundred cases of healthy postpartum women were randomly divided into two groups :control group and training group .The control group received the customary education ,and the training group received pelvic floor rehabilitation training . At 6 and 12 weeks postpartum ,levator hiatus area ,thickness of the levator ani muscle ,bladder neck mobility ,and bladder posterior horn were measured with three-dimensional transperineal ultrasound in all the subjects . Meanwhile ,the muscle strength situations were tested . Results At 12 weeks postpartum ,the anal levator hiatal area ,bladder neck mobility and bladder posterior horn in the training group were lower than those of the control group[ ( 21 .6 ± 3 .2) cm 2 vs ( 25 .6 ± 2 .4 ) cm 2 ,( 27 .9 ± 5 .3) mm vs ( 31 .5 ± 5 .9) mm ,( 126 .3 ± 21 .2)° vs (135 .3 ± 11 .6)°] ( P < 0 .05) . Compared with control group ,the thickness of the levator ani muscle increased in training group [ ( 13 .6 ± 2 .3) mm vs ( 15 .3 ± 2 .5) mm ] ( P < 0 .05) . The incidence of stress urinary incontinence in the training group ( 5% ) was significantly lower than the control group ( 12 .5% ) at 12 weeks postpartum ( χ2 = 5 .487 , P = 0 .025) . The muscle strength had no significant difference at 6 weeks postpartum . At 12 weeks postpartum ,the pass rate of class Ⅰ muscle fiber was 78 .5% ,and that of class Ⅱ muscle fiber was 83 .3% in the training group ;the pass rate of class Ⅰ muscle fiber was 28 .5% ,and class Ⅱ muscle fiber was 37 .3% in the control group , the improvement was significant at 12 weeks postpartum . Conclusions The result of the transperineal real-time ultrasonographic evaluation of post-natal pelvic floor rehabilitation training has high consistency with the measurement of muscle strength . The ultrasound examination is simple and accurate ,and has highly applicable value in evaluating the effect of post-pelvic rehabilitation training .

Relationship between vitamin D and lung function, physical performance and balance on patients with stage I-III chronic obstructive pulmonary disease / Relação entre vitamina D e função pulmonar, desempenho físico e equilíbrio em pacientes em estágio I a III de doença pulmonar obstrutiva crônica

Summary Objectives: vitamin D is important for muscle function and it affects different aspects of muscle metabolism. This study aim to determine whether serum 25(OH) D levels are related to lung functions, physical performance and balance in patients with chronic obstructive pulmonary disease (COPD). Methods: in 90 patients with COPD and 57 healthy controls lung function tests, physical performance tests (time up and go, gait velocity test, sit-to-stand test, isometric strength, isokinetic strength), static (functional reach test) and dynamic (time up and go) balance tests and the association of 25(OH)D levels with lung functions, physical performance and balance were evaluated. Results: the COPD patients had significantly more deficit in physical function and balance parameters, and in dynamic balance test (p<0.005). Isokinetic knee muscle strength (flexor and extensor) in COPD patients was significantly lower than in the controls (p<0.05); FEV1 (p=0.008), FVC (p=0.02), FEV1/FVC (p=0.04), TLC (p=0.01) were lower in COPD patients with vitamin D deficiency [25(OH) D less than 15ng/mL] than in COPD patients without vitamin D deficiency. Hand grip test (p=0.000) and isokinetic knee muscle strength (flexor and extensor) (p<0.05) were also lower in COPD patients with vitamin D deficiency. Vitamin D deficiency was more pronounced in patients with stage III COPD (p<0.05). Conclusion: patients with COPD had worst physical functioning, poor balance and less muscle strength. Severe disturbed lung and peripheral muscle functions are more pronounced in COPD patients with vitamin D deficiency. .

Resumo Objetivos: a vitamina D é importante para a função muscular e afeta diferentes aspectos do metabolismo muscular. O objetivo é determinar se os níveis séricos de 25 (OH) D estão relacionados com as funções pulmonares, desempenho físico e equilíbrio em pacientes com doença pulmonar obstrutiva crônica (DPOC). Métodos: em 90 pacientes com DPOC e 57 controles saudáveis, testes de espirometria, testes de desempenho (tempo de levantar e ir, teste de velocidade da marcha, teste sitto-stand, força isométrica, força isocinética) e testes de estática (teste de alcance funcional) e dinâmica (tempo de levantar e ir) de equilíbrio foram realizados; e foram avaliados a associação de níveis de 25 (OH) D com as funções pulmonares, desempenho físico e equilíbrio. Resultados: os pacientes com DPOC apresentaram significativamente mais déficit nos parâmetros de função e equilíbrio físico, e no teste de equilíbrio dinâmico (p<0,005). Força muscular isocinética do joelho (flexores e extensores) em pacientes com DPOC foi significativamente menor do que nos controles (p<0,05); VEF1 (p=0,008), CVF (p=0,02), VEF1/CVF (p=0,04), CPT (p=0,01) foram mais baixos em pacientes com DPOC e com deficiência de vitamina D [25 (OH) D menor do que 15 ng/ml] do que em pacientes com DPOC sem deficiência de vitamina D. Os resultados do teste da força de preensão manual (p=0,000) e força muscular isocinética do joelho (flexor e extensor) (p<0,05) também foram menores nos pacientes com DPOC e com deficiência de vitamina D. A deficiência de vitamina D foi mais pronunciada em pacientes em estágio III da DPOC (p<0,05). Conclusão: pacientes com DPOC tiveram pior desempenho físico, falta de equilíbrio e menor força muscular. Perturbações graves das funções pulmonares e musculares periféricas são mais pronunciadas em pacientes com DPOC e com deficiência de vitamina D. .

Double Fold Affected by Levator Function in Simultaneous Double Eyelid Blepharoplasty with Blepharoptosis Surgery

PURPOSE: To evaluate height and symmetry of double folds following simultaneous levator palpebral muscle resection and double eyelid blepharoplasty for correction of blepharoptosis. METHODS: We retrospectively studied 400 eyes of 286 patients who underwent simultaneous surgeries for double eyelid construction and correction of blepharoptosis from January 2006 to December 2011. All the patients were divided into three groups based on levator palpebrae muscle function: group A consisted of 82 eyes whose Levator Function Test (LFT) was 5 cm or less, group B consisted of 115 eyes whose LFT was between 5 and 10 cm, group C consisted of 203 eyes whose LFT was over 10 cm. For each group, we evaluated the preoperative marginal reflex distance 1 (MRD1), surgical methods, the postoperative height and symmetry of the double folds, and additional operations for correcting blepharoptosis. RESULTS: Blepharoptosis surgery was performed in all groups by simultaneous levator resection and double eyelid blepharoplasty in all groups. Postoperative asymmetric double fold was the most common outcome observed in the poor levator function group A. Blepharoptosis under-correction was the most common cause of asymmetric double fold and its occurrence was statistically different between the three groups. The other causes were skin redundancy, brow elevation, double fold loosening, and blepharoptosis over-correction. CONCLUSIONS: The height of a double eyelid can be changed postoperatively by changing levator palpebrae muscle function. In cases of poor levator function, the levator palpebrae muscle is positioned slightly lower than the normal double fold. This condition may result in further relapse or recurrence in the poor levator function group. Also, levator function should be considered among the diverse factors that determine the height of the double fold.

Sarcopenia, exercise and muscle reconstruction / 中国组织工程研究

BACKGROUND:Sarcopenia is the muscle loss in the elderly with aging, and it is closely related to the degradation of muscle function in the elderly. The research on the mechanism of sarcopenia as wel as effect of movement intervention is developed. OBJECTIVE:To summary the mechanisms of sarcopenia cel level as wel as the effect of movement intervention. METHODS:A computer-based retrieval was conducted on CNKI database and PubMed database for literatures on sarcopenia and elderly resistance training from January 2000 to December 2012. The key words were “sarcopenia, muscle, resistance training, aging, protein metabolism”. The literatures on sarcopenia, protein metabolism and resistance training were included, and the obsolete and repetitive literatures and the literatures lack of credibility were excluded. Final y, 58 literatures were included for analysis. RESULTS AND CONCLUSION:Resistance training can inhibit sarcopenia to a certain extent, so that to increase muscle mass in the elderly and promote the recombinant of motor units. But the recombinant is limited to the mutual conversion between the type Ⅱa and Ⅱb fibers. Resistance training combined with protein supplement can effectively promote elderly muscle reconstruction;the elderly muscle anabolic response confrontation reaction after resistance training is slower than young people, but the inflammatory response after training is stronger than younger people. However, Omega-3 has a good effect on the elimination of such inflammatory response.