Effects of preventive cardiac pacing on hemodynamic and major adverse cardiovascular events during hospitalization in patients with acute inferior wall myocardiac infarction during emergency percutaneous coronary intervention / 实用医学杂志

Objective To evaluate the effects of preventive cardiac pacing on acute inferior wall myocardiac infarction ( AIMI ) . Methods A total of 52 patients were given preventive cardiac pacing before Percutaneous coronary intervention (PCI) (group T),while another 68 patients were not (group N).Heart rate and average blood pressure level before reperfusion, average blood pressure level after reperfusion,TIMI flow grade before and after reperfusion,the incidence of malignant ventricular arrhythmia after reperfusion and adverse cardiovascular events during hospitalization were compared in two groups. Results There were no significant differences in heart rate before reperfusion , average blood pressure levels before and after reperfusion , and the TIMI flow grade before and after reperfusion between two groups. The malignant ventricular arrhythmia after reperfusion in group T was significantly higher than that in group N while heart failure and nonfatal myocardial infarction were no significantly different between them. Mortality rate and mortality rate of cardiovascular disease in group T were higher than those in group N, but there were no significant differences between them. Conclusions The temporary cardiac pacing has no additional preventive effect on hemodynamic , but increases the occurrence of malignant ventricular arrhythmia , and the risk of death and cardiovascular events.

Successful Primary Percutaneous Coronary Intervention for Acute Myocardial Infarction in a Patient with Dextrocardia and Hypertrophic Cardiomyopathy

We report a case of a 69-year-old man presenting with acute right chest pain radiating to the right shoulder. Physical examination revealed a right sided apex beat with a palpable liver on the left side. Reversed normalizing electrocardiogram are presented, allowing for correct diagnosis of an acute anterior myocardial infarction. Dextrocardia with situs inversus is an uncommon congenital condition, the patient also diagnosed hypertrophic cardiomyopathy by two dimensional echocardiography. Successful percutaneous coronary intervention was performed and the patient was discharged after uneventful recovery.

Autologous myoblasts transplantation improves heart function after myocardiac infarction / 中南大学学报(医学版)

Objective To determine whether autologous skeletal myoblasts implantation improves the cardiac function after myocardial infarction and the possible mechanism. Methods Myocardial infarction was induced by ligation of the left anterior descending coronary artery in rabbits. At 2 weeks, 1. 34 × 107 to 1.75 × 107 autologous skeletal myoblasts were infused into the lesion via direct intramuscular injection. In the control group, the postinfarction hearts were infused with medium alone. Buxco invasive cardiac function testing and histopathological examination were utilized to evaluate the functional and structural changes in the myocardium 4 weeks later. Results Both maximum rising rate of the left intraventricular pressure [+dp/dtmax,( 1 217.77 +89.91 )mmHg/s vs. (897.83 ±70.04) mmHg/s] and maximum falling rate of the left intraventricular pressure [- dp/dtmax,( -1174.58 ± 91.5 ) mmHg/s vs. ( - 753.67 ± 69.66 ) mmHg/s] were improved in the myoblast transplanted group compared with medium infusion group. The positive desmin immunostaining skeletal myofibers in the myocardium were found throughout the infracted areas and the border zone. Conclusion Autologous skeletal myoblasts can establish muscle tissue when transplanted into postinfarction hearts, and this mucle can treat myocardiac infarction effectively.

Evaluation of Chlamydia Antibody Using Micro-immunofluorescence in Acute Myocardiac Infarction / 대한진단검사의학회지

BACKGROUND: Chlamydia pneumoniae can cause chronic inflammation in the arterial wall. C. pneumoniae infection has been investigated as a new risk factor for acute myocardiac infarction (AMI), afatal outcome of coronary artery occlusion. METHODS: IgG and IgM for C. pneumoniae using micro-immunofluorescence were evaluated in 80 AMI patients and 46 controls without coronary arterial disease. RESULTS: Chronic infection, defined by equal or higher than 1: 32 titers of IgG of C. pneumoniae, was observed in 51.3% (41/80) in AMI and 17.4% (8/46) in controls (P<0.05). None of the subjects showed acute infection, defined by equal or higher than either 1: 16 of IgM or 1: 512 of IgG of C. pneumoniae. CONCLUSIONS: Chronic C. pneumoniae infection was significantly more common in AMI patients compared to the controls.

Analysis of Classical Risk Factors and Homocysteine Level in Acute Myocardiac Infarction / 임상검사와정도관리

BACKGROUND: Hyperhomocysteinemia can be treated and is more preventable compared to the classical risk factors such as age, sex, smoking, obesity, diabetes mellitus, hypertension and hyperlipidemia. METHODS: Serum homocysteine levels were analyzed with fluorescence polarized immunoassay (IMx, Abbott Diagnostics) for 63 patients with acute myocadiac infarction (AMI) and 43 controls who did not have coronary arterial disease from 1997 to 1998. Medical records were reviewed to compare the classical risk factors between the two groups. RESULTS: The mean homocysteine level of AMI was 9.3 +/-5.3 micronmol/L, which is slightly lower than 9.8+/-5.8 micronmol/L in the control group (P>0.05). Other risk factors were not significantly different between the two groups with the exception of serum cholesterol level. CONCLUSIONS: It is concluded that hypercholesterolemia is an important risk factor for AMI, while serum homocysteine level is not, as far as this study goes. Well planned follow up studies are needed to establish the degree to which homocysteine is a risk factor for AMI.

Effect of simvastatin on RhoA expression and cardiac remodeling with in acute myocardiac infarction rats / 第三军医大学学报

Objective To investigate the effects of simvastatin on the abatement of the mRNA,protein expression of RhoA and the improvement of the cardiac remodeling and cardiac disfunction after the myocardiac infarction in rats.Methods Rats were divided into 3 groups: the control group,the myocardiac infarction group and Simvastatin intervened group.After 8 weeks,cardiac weight index and hemodynamics were observed,mRNA and protein expression of RhoA in cardiac muscles was measured. Results Compared with the control group,the cardiac weight index and the mRNA and protein expression were increased in rats with myocardiac infarction and the hemodynamics was worsened(P

Application of exercise stress test after acute myocardial infarction / 中国康复理论与实践

@#ObjectiveTo investigate application of exercise stress test after acute myocardial infarction(AMI). Methods32 patients with AMI performed exercise stress test adopted the Bruce protocol in 16 days-8weeks after onset, at the same time cardiac functional capacity was measured.ResultsThe stress test was positive in 17 cases, whose cardiac functional capacity was 1.5-7 METs,and it was negative in 15 cases, whose cardiac functional capacity is 4-12 METs.Conclusions①Second class amount limited exercise stress test is safe to adaptive AMI patients. ②Cardiac functional capacity measurement is benefit to instruct patient rehabilitation exercise. ③Exercise stress test is valuable to estimate prognosis of AMI.

A Preliminary Study on Clinical Characteristics and Prognosis of Painless Acute Myocardiac Infarction: A Report of 32 Cases / 广州中医药大学学报

Objective To investigate the clinical characteristics, TCM syndrome differen tiation and short_term prognosis of painless acute myocardiac infarction (AMI). Methods Restrospective analysis was carried out in 32 patients with painless AMI (Group A) and 30 cases of painful AMI in the same period served as Group B. Results In Group A, clinical manifestations were latent, infarct places mai nly located in the inferior wall, right ventricle and posterior wall of the hear t ( 65.6% ), and yang_Qi deficiency syndrome and Qi_yin defic iency syndrome occupied 65.6% of painless AMI. Blood stasis syn drome and phlegm syndrome occupied 70.0% of painful AMI. The co ncurrent incidence of diabetes mellitus was higher in Group A than Group B. So d id the mortality and the incidence of heart failure. Cardiogenic shock and heart failure were the main death causes of painless AMI. Conclusion The above r esults will supply evidence for the combined treatment of painless AMI.

Primary intracranial hemorrhage presenting as acute myocardial ischemic syndrome / 대한내과학회지

A 44 years old woman was admitted to Inha University hospital in semicomatose state. An electrocardiogram (ECG), taken in the emergency room, showed ST segment elevation in the precordial leads. She underwent a urgent echocardiography. It showed that there was akinesia of anteroseptal segment from the mid left ventricle to the apex and inferior segment from the mid left ventrile to the lower mid left ventricle. With the impression of acute myocardial infarction (AMI), she underwent a urgent coronary angiography. There was no significant luminal narrowing of the right or the left coronary arteries but the left ventriculography revealed akinesia of anterolateral and diaphragmatic segments of the left ventricle. Computerized tomography (CT) of the brain, taken shortly after coronary angiography, showed subarachnoid hemorrhage. The abnormal ECG and echocardiography findings, simulating acute myocardial infarction, were assumed to be caused by coronary vasospasm derived from subarachnoid hemorrhage accompanied by massive adrenergic discharge.

Effect of Intravenous Injection of Radix Astragali seu Hedysari on Acute Myocardiac Infarction in Anesthetized Dogs / 中成药

Objective:To investigate the protective effect of Intravenous Injection of Radix Astragali seu Hedysari on acute myocardiac infarction (AMI) in anesthetized dogs. Methods: Twenty health dogs were treated by ligating descending anterior of coronary with two-step method. The changes of electrocardiogram before and after ligation were recorded. After 4 hours myocardium were taken out and dyed with NBT to make sure of the extent of myocardiac infarction.Results: Intravenous Injection of Radix Astragali seu Hedysari could decrease the lethality of AMI, ameliorated ST changes on electrocardiogram induced by AMI, and reduced infarction area. Conclusions: Intravenous Injection of Radix Astragali seu Hedysari is effective in the treatment of AMI in anesthetized dogs.